Results 81 to 90 of about 307,259 (304)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
New Bounds on Crossing Numbers [PDF]
The notation \(f(n)\ll g(n)\) means that, as \(n\) goes to infinity, \(g(n)/f(n)\) goes to infinity also. For \(g\geq 0\), let \(S_g\) denote the closed orientable 2-manifold of genus \(g\), with \(\text{cr}_g(G)\) the minimum number of crossing points among all drawings of the graph \(G\) on \(S_g\).
János Pach +2 more
openaire +2 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Cubicity, degeneracy, and crossing number
A $k$-box $B=(R_1,...,R_k)$, where each $R_i$ is a closed interval on the real line, is defined to be the Cartesian product $R_1\times R_2\times ...\times R_k$. If each $R_i$ is a unit length interval, we call $B$ a $k$-cube. Boxicity of a graph $G$, denoted as $\boxi(G)$, is the minimum integer $k$ such that $G$ is an intersection graph of $k$-boxes ...
Abhijin Adiga +2 more
openaire +4 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Crossing and Weighted Crossing Number of Near-Planar Graphs [PDF]
A nonplanar graph G is near-planar if it contains an edge e such that G − e is planar. The problem of determining the crossing number of a near-planar graph is exhibited from different combinatorial viewpoints. On the one hand, we develop min-max formulas
Cabello, Sergio +3 more
core +1 more source
Marking Algorithms in Permutation Tableaux and Transformations on Linked Partitions
In this paper, we focus on the internal structural characteristics of permutation tableaux and their correspondence with linked partitions. We begin by introducing new statistics for permutation tableaux, designed to thoroughly describe various ...
Carol Jian Wang, Meryl Nan Wang
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Pach and Toth [PT] introduced a new version of the crossing number parameter, called the degenerate crossing number, by considering proper drawings of a graph in the plane and counting multiple crossing of edges through the same point as a single crossing when all pairwise crossings of edges at that point are transversal. We propose a related parameter,
openaire +2 more sources

