Results 61 to 70 of about 624,423 (312)

Mitotic crossover promotes leukemogenesis in children born with TEL-AML1 via the generation of loss of heterozygosity at 12p

La Pediatria Medica e Chirurgica, 2015
TEL-AML1 (ETV6-RUNX1) fusion gene which is formed prenatally in 1% of the newborns, is a common genetic abnormality in childhood Bcell precursor acute lymphoblastic leukemia.
Ivan Ivanovski, Livia Garavelli, Olivera Djurić, Aleksandar Ćirović, Dejan Škorić, Petar I. Ivanovski   +5 more
doaj   +1 more source

Creation of doubled haploid lines of maize Zea mays L. by resynthesis from a tetraploid population

Биотехнология и селекция растений, 2023
The search for new, effective methods for broadening the genetic polymorphism of the original breeding material remains one of important problems of hybrid maize breeding.
A. V. Ulyanov, D. S. Kutsev, V. V. Vasipov, Kh. R. Mamadova, M. Yu. Khakulova, S. F. Israfilova, M. R. Firsova, A. V. Karlov, E. B. Khatefov   +8 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Accurate recombination estimation from pooled genotyping and sequencing: a case study on barley

BMC Genomics, 2022
Sexual reproduction involves meiotic recombination and the creation of crossing over between homologous chromosomes, which leads to new allele combinations. We present a new approach that uses the allele frequency differences and the physical distance of
Michael Schneider, Federico Casale, Benjamin Stich   +2 more
doaj   +1 more source

Keel petal incision: a simple and efficient method for genetic crossing in Medicago truncatula

Plant Methods, 2014
BackgroundGenetic crossing is an essential tool in both forward and reverse genetic approaches to understand the biological functions of genes. For Medicago truncatula (barrel medic) various crossing techniques have been used which differ in the methods ...
V. Veerappan, Khem Kadel, Naudin Alexis, Ashley Scott, Igor Kryvoruchko, Senjuti Sinharoy, Mark Taylor, M. Udvardi, R. Dickstein   +8 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Improvement of the Genome Editing Tools Based on 5FC/5FU Counter Selection in Clostridium acetobutylicum

Microorganisms, 2023
Several genetic tools have been developed for genome engineering in Clostridium acetobutylicum utilizing 5-fluorouracil (5FU) or 5-fluorocytosine (5FC) resistance as a selection method.
Eglantine Boudignon, Céline Foulquier, Philippe Soucaille   +2 more
doaj   +1 more source

Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map [PDF]

Genome Biology, 2008
Abstract Background Trypanosoma brucei is the causative agent of human sleeping sickness and animal trypanosomiasis in sub-Saharan Africa, and it has been subdivided into three subspecies: Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, which cause sleeping sickness in humans, and the ...
Cooper, A., Tait, A., Sweeney, L., Tweedie, A., Morrison, L., Turner, C.M.R., MacLeod, A.   +6 more
openaire   +4 more sources

Efficient targeted recombination with CRISPR/Cas9 in hybrids of Caenorhabditis nematodes with suppressed recombination

BMC Biology, 2023
Background Homology-based recombination (HR) is the cornerstone of genetic mapping. However, a lack of sufficient sequence homology or the presence of a genomic rearrangement prevents HR through crossing, which inhibits genetic mapping in relevant ...
Dongying Xie, Bida Gu, Yiqing Liu, Pohao Ye, Yiming Ma, Tongshu Wen, Xiaoyuan Song, Zhongying Zhao   +7 more
doaj   +1 more source

Genetics of inbred Drosophila melanogaster VI. Crossing-over in secondary non-disjunction exceptionals [PDF]

Hereditas, 2008
Although Bridges (1916, Genetics 1: 1–52 and 107–183) found recombinants among exceptional XXY females in tests of secondary non-disjunction, he misinterpreted their origin and claimed that true secondary non-disjunction resulted in XX eggs with non-crossover chromosomes.
openaire   +2 more sources