Results 71 to 80 of about 110,044 (258)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Genetics of inbred Drosophila melanogaster VI. Crossing-over in secondary non-disjunction exceptionals [PDF]
Hereditas, 2008 Although Bridges (1916, Genetics 1: 1–52 and 107–183) found recombinants among exceptional XXY females in tests of secondary non-disjunction, he misinterpreted their origin and claimed that true secondary non-disjunction resulted in XX eggs with non-crossover chromosomes.
openaire +2 more sources
The Plant GenomeGenome‐wide introgression and substitution lines have been developed in many plant species, enhancing mapping precision, gene discovery, and the identification and exploitation of variation from wild relatives.
Richard Horsnell +9 more
doaj +1 more source
Genetic Renal Diseases: The Emerging Role of Zebrafish Models
Cells, 2018 The structural and functional similarity of the larval zebrafish pronephros to the human nephron, together with the recent development of easier and more precise techniques to manipulate the zebrafish genome have motivated many researchers to model human
Mohamed A. Elmonem +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
From Crossing-Over to Developmental Genetics
, 2023 CURT STERN, UNIVERSITY OF CALIFORNIA, BERKELEY, CALIF.
openaire +1 more source
Scientific ReportsModern agriculture, based on biparental crop varieties have contributed tremendously to the world’s food supply. However, the strategy is also being challenged due to stagnation in yield growth, climate change, susceptibility to biotic and abiotic ...
Parashuram Patroti +6 more
doaj +1 more source
Floral biology and reproductive mechanisms of Mussambê (Cleome spinosa Jacq) aiming at the plant breeding [PDF]
Biotemas, 2007 Some plants from Cleome genus in Capparaceae family are used as medicinal and ornamental plants. The aim of this work was to study the fl oral biology and the reproductive mechanisms of C. spinosa to the plant breeding. Anthesis occurred between 17:30 to
Cláudio Lúcio Fernandes Amaral +2 more
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