Results 61 to 70 of about 110,044 (258)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Heritability and Genetic Variance Components in Sunflower Single Cross Hybrids [PDF]
In order to estimate genetic parameters in 16 Sunflower single cross hybrids obtained from crossing of 4 cytoplasmic male sterile and 4 fertility restorer lines, a North Carolina Design II was conducted using RCBD design with 3 replications at Khoy ...
AR Tarinejad +3 more
doaj
The purposes of this study were to determine the percentage of out-crossing, isolation distance and pollinator insect species for cotton (Gossypium hirsutum L.) seed production in the Aydin region in Turkey.
Taner Bozbek +5 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Stochastic Model for Genetic Recombination because of Crossing over and Chromatid Exchange
Genetic recombination by crossing over and chromatid exchange in eukaryotes is one of the major events leading to variance, among individuals of a population set. Therefore, quantification of the recombination would be central to the understanding of the genetic diversity, genealogical differences, disease variants and its maintenance within the ...
Rajeev Sharmah, Tazid Ali, Jugal Gogoi
openaire +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
INHERITANCE OF HYPOCOTYL COLOUR AND PUBESCENCE IN MUNGBEAN (VIGNA RADIATA (L.) WILCZEK) [PDF]
The mode of inheritance of seedling color and plant pubescence was studied in two crosses among three parents, which differed for these traits. The results have revealed that purple seedling color was dominant over green seedling color and pubescence was
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source

