Results 101 to 110 of about 54,169 (252)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Water quality monitoring during the construction of the M3 motorway in Ireland [PDF]
, 2011 The M3 motorway in Ireland was constructed between the years 2007 and 2010. The motorway crosses the River Boyne, which is a designated salmonid water under the EU Freshwater directive, and its tributaries.
Michael Bruen +10 more
core +1 more source
The effects of selected factors on pedestrian crossings in urban areas
MATEC Web of Conferences, 2017 Pedestrian crossings are designed to help pedestrians cross a road. There are at-grade pedestrian crossings with or without traffic lights and grade separated crossings such as subways and footbridges.
Gumińska Lucyna
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Local Impacts of Road Crossings on Puget Lowland Creeks
, 2004 This fact sheet reviews the current state of research on road-induced damage to streams, and some of the most promising approaches for mitigation. Effects of road crossings, channel confinement, and riparian buffers are reviewed.
Alvolio, Christina
core
Ordering Metro Lines by Block Crossings
Journal of Graph Algorithms and Applications, 2015 A problem that arises in drawings of transportation networks is to minimize the number of crossings between different transportation lines. While this can be done efficiently under specific constraints, not all solutions are visually equivalent. We
Martin Fink +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
“The rise and fall of a chest, snores bellowing into the celeste, the sheep slowly realize they no longer need to jump into the dreamt sky, return to the barn to rest, no longer on their quest.” This is an excerpt from pages 5 and 6 of Dream Sheep, a ...
Foder, Sophia Grace
core +1 more source
Getting the Attention of Drivers Back on Passive Railway Level Crossings : Evaluation of Advanced Flashing Lights [PDF]
, 2019 Improving safety at railway level crossings remains a priority for the rail industry internationally, as they remain a significant hazard. A high proportion of collisions occur at passive level crossings, because of their high prevalence and their lower ...
Watling, Christopher N. +4 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source