Results 91 to 100 of about 54,169 (252)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Cultural Studies : Mediterranean Crossings

open access: yes, 2008
A 1000-word review of Mediterranean Crossings: The Politics of an Interrupted Modernity by Iain Chambers (Duke UP ...
Gislason, Kari
core  

Protectionism\u27s Paradox: Catalyzing Change in the Global South

open access: yes
This paper examines the economic and geopolitical implications of Donald Trump’s proposed sweeping tariffs on the Global South, contextualizing them within broader global trends of protectionism and multipolarity. Using case studies such as the 2018 U.S.-
Jerome, Wyatt
core   +1 more source

An Imposter Among Shakespeare’s Fools: The Tempest’s Trinculo [PDF]

open access: yes
The plays of William Shakespeare often feature a fool who resembles the historic jester of the Elizabethan era. Overtime, the Shakespearean fool developed into a powerful character who challenges and questions both the other characters in the play as ...
Polenchuk, Lily
core   +1 more source

Editorial note

open access: yesCrossings, 2008
Crossings: ULAB Journal of English Studies Department of English and Humanities University of Liberal Arts Bangladesh Volume 1, Number 1 ...
Mohit Ul Alam Mohit Ul Alam
doaj  

LIGHTING ON UNREGULATED PEDESTRIAN CROSSING

open access: yesВестник СибАДИ, 2019
Introduction. The actual problem in Russia is the accident rate at pedestrian crossings. The authors conduct the research about the lighting conditions on unregulated pedestrian crossings to improve safety and to identify compliance with current ...
S. N. Pavlov, Yu. V. Pavlova
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Boundaries of Self: Ecopsychology and Autistic Experience [PDF]

open access: yes
Ecopsychology provides numerous ways to define the boundary between self and environment, including the idea of an expanded self that incorporate the natural world into one’s self-perception.  Within ecopsychology this concept is primarily ...
Jamin-Lynn, Larissa
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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