Results 71 to 80 of about 68,815 (309)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cross and Learn: Cross-Modal Self-supervision [PDF]

, 2019
GCPR ...
Nawid Sayed, Biagio Brattoli, Björn Ommer   +2 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

On-road driving studies to understand why drivers behave as they do at regional rail level crossings

, 2013
Improving safety at rail level crossings is an important part of both road and rail safety strategies. While low in number, crashes between vehicles and trains at level crossings are catastrophic events typically involving multiple fatalities and serious
Salmon, P.B., Stanton, Neville A., Filtness, A J, Lenne, M G, Salmon, Paul M., Salmon, P M, Beanland, Vanessa, Beanland, V., Lenne, M.G., Stanton, N A, Filtness, A., Filtness, Ashleigh, Lenné, Michael G.   +12 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The behaviour of railway level crossings: insights through field monitoring

The development of reliable methods for measuring deflections as trains pass has enabled valuable insights into railway track behaviour to be gained.
Powrie, W., Roberts, C., Watson, G.V.R, Le Pen, L., Yeo, G., Weston, P.   +5 more
core   +1 more source

Water quality monitoring during the construction of the M3 motorway in Ireland

, 2011
The M3 motorway in Ireland was constructed between the years 2007 and 2010. The motorway crosses the River Boyne, which is a designated salmonid water under the EU Freshwater directive, and its tributaries.
Michael Bruen, O'Sullivan, J. J., Cocchiglia, Letizia, O\u27Sullivan, J. J., Kelly-Quinn, Mary, Purcell, Patrick J., John O'Sullivan, Letizia Cocchiglia, Patrick Purcell, Mary Kelly-Quinn, Bruen, Michael   +10 more
core   +1 more source

Identification of unavoided crossings in nonadiabatic photoexcited dynamics involving multiple electronic states in polyatomic conjugated molecules [PDF]

, 2012
Radiationless transitions between electronic excited states in polyatomic molecules take place through unavoided crossings of the potential energy surfaces with substantial non-adiabatic coupling between the respective adiabatic states.
Sergei Tretiak, Roitberg, Adrián, Nelson, Tammie, Tretiak, Sergei, Adrian E. Roitberg, Fernández Alberti, Sebastián, Tammie Nelson, Sebastian Fernandez-Alberti   +7 more
core   +1 more source

Moment Crossings as Related to Density Crossings

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1965
Summary In this paper we show how the number of moment crossings of two symmetrical densities is related to the number of crossings of the densities. This generalizes a result of Fisher recently proved by Finucan (1964).
Marsaglia, G., Marshall, A. W., Proschan, F.   +2 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source