Results 61 to 70 of about 68,815 (309)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Measuring driver responses at railway level crossings
, 2011 Railway level crossings are amongst the most complex of road safety control systems, due to the conflicts between road vehicles and rail infrastructure, trains and train operations. Driver behaviour at railway crossings is the major collision factor. The
Angela Wallace +5 more
core +1 more source
SELECTION OF LEEK FOR THE MIDLAND OF RUSSIA AT CULTIVATION NO SEEDLING METHOD
Овощи России, 2018 Leek very ancient culture which was widely applied in cookery and as remedy still by ancient Egyptians, Greeks and Romans. Now the leek is widespread in countries of Western Europe and North Africa, in the USA, Canada, Australia.
A. F. Agafonov, М. V. Dubova
doaj +1 more source
Equity trading by institutional investors: To cross or not to cross? [PDF]
Journal of Financial Markets, 2002 The proliferation of market places and trading methods is a striking feature of current equity markets. A stated goal of all the new trading arrangements is to reduce transactions costs. We investigate costs in one new market place, the crossing network.
Ødegaard, Bernt Arne, Næs, Randi
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Sinofuturism as Speculative Design
, 2023 The video essay Sinofuturism (1839–2046 AD) by artist Lawrence Lek is difficult to categorize. It is an hour-long film collaging documentaries, news clips, video games, and CGI. Most often exhibited and discussed in a (new) media art context, it has been
Lau, Ashley, Ashley Lau
core +1 more source
Crossings“Mind the gap”: the phrase is familiar on the London Underground, as a warning to passengers boarding or leaving trains. The gap in question is between train and platform.
Joseph Brooker
doaj +1 more source
Овощи России, 2018 The problem of stability of plants of the onion to the most nocuous diseases acquired in the world a paramount value. Untrue mealy dew or peronosporoz onion related to their number, astonishes many kinds of the sort Allium L.
A. F. Agafonov +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Lighting requirements for pedestrian crossings – positive contrast [PDF]
MATEC Web of Conferences, 2019 For many years now in Poland there has been a large number of road accidents at pedestrian crossings during night periods [5, 11]. One of the technical solutions that can improve this condition is the use of proper lighting for pedestrian crossings.
Tomczuk Piotr +3 more
doaj +1 more source