Results 131 to 140 of about 54,169 (252)

Cross-cultural, cross-societal and cross-national research

, 1993
Historical Social Research, 18(2), 6 ...
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The Linen-Clad Body: Changing Meanings in Narratives of Health, Cleanliness, and Identity in Early Modern Europe and Later Colonial Contexts

This thesis explores the evolving significance of linen in Early Modern Europe and its later role in colonial settings, examining how the fabric was intertwined with narratives of health, cleanliness, and identity.
Persaud, Caitlin
core   +1 more source

Editorial note

Crossings, 2009
Crossings: UIAB Journal of English Stadies Department of English and Humanities University of Liberal Arts Bangladesh Volume 2, Number 1 ...
Mohit Ul Alam Mohit Ul Alam
doaj  

Effectiveness of raised safety platforms: a systematic review of literature

Transportation Research Interdisciplinary Perspectives
Raised safety platforms (RSPs) can offer benefits, including increased speed and reduced crash risk. However, they may also have drawbacks, including riding discomfort and the potential for hazardous maneuvers.
Fahimeh Golbabaei, Ali Mirhashemi, Wahi Rabbani, Zeke Ahern, Simon Denman, Alexander Paz   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Motorist behaviour at railway level crossings : the present context in Australia [PDF]

, 2008
Railway level crossing collisions in Australia are a major cause of concern for both rail and road authorities. Despite the fact that the number of railway crash fatalities in Australia has fallen in recent years, level crossing collisions constitute a ...
Wallace, Angela M.
core  

Identifying MESSENGER Magnetospheric Boundary Crossings Using a Random Forest Region Classifier

Journal of Geophysical Research: Machine Learning and Computation
We present a new list of bow shock and magnetopause crossings based on automated region classification for the MESSENGER (Mercury Surface, Space Environment, Geochemistry and Ranging) mission.
Daragh M. Hollman, Caitríona M. Jackman, Katarina Domijan, Charles F. Bowers, Simon J. Walker, Matthew J. Rutala, Alexandra R. Fogg   +6 more
doaj   +1 more source