Results 271 to 280 of about 185,186 (338)

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman   +7 more
wiley   +1 more source

GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome. [PDF]

open access: yesNat Commun
Roeselová A   +7 more
europepmc   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

open access: yesAdvanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova   +7 more
wiley   +1 more source

Diverse thioether macrocyclized peptides through a radical SAM maturase. [PDF]

open access: yesProc Natl Acad Sci U S A
Eastman KAS, Roberts AG, Bandarian V.
europepmc   +1 more source

Base-resolution binding profile prediction of proteins on RNAs with deep learning. [PDF]

open access: yesNucleic Acids Res
Liu X   +7 more
europepmc   +1 more source

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