Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman +7 more
wiley +1 more source
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome. [PDF]
Roeselová A +7 more
europepmc +1 more source
A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova +7 more
wiley +1 more source
Diverse thioether macrocyclized peptides through a radical SAM maturase. [PDF]
Eastman KAS, Roberts AG, Bandarian V.
europepmc +1 more source
Structure-Property Relationships in Epoxy-Anhydride Systems: A Comprehensive Comparative Study of Cycloaliphatic, Novolac, and Aromatic Prepolymers. [PDF]
Patry S +5 more
europepmc +1 more source
Base-resolution binding profile prediction of proteins on RNAs with deep learning. [PDF]
Liu X +7 more
europepmc +1 more source
The compendium of Arabidopsis thaliana GLYCINE-RICH RNA-BINDING PROTEIN 8 in vivo targets determined by iCLIP. [PDF]
Meyer K +3 more
europepmc +1 more source
Optimization of the mechanical performance of TDI-based polyurethanes <i>via</i> orthogonal design and response surface methodology. [PDF]
Hong T, Kang Y, Tian P, Xuan F.
europepmc +1 more source
Reply to Rattanapitoon et al., "Reconsidering the <i>Toxoplasma gondii</i> interactome: opportunities beyond crosslinking mass spectrometry". [PDF]
Tomita T +5 more
europepmc +1 more source

