Results 141 to 150 of about 179,339 (238)

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

Advanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv, Yu Cao, Yuhan Wang, Yunhao Wu, Yingying Zhang, Kuanghao Ye, Xian Qiu, Qingfang Sun, Liuguan Bian, Halimureti Paerhati, Valerie Voon, Shikun Zhan, Bomin Sun   +12 more
wiley   +1 more source

Persistent carry-over in a two-period randomised crossover design for behavioural interventions without the expectation of return to baseline after intervention cessation. [PDF]

Trials
Kulnik ST, Carrozzo AE, Crutzen R.
europepmc   +1 more source

Asymmetric Mass Transport in Polybromide Ionic Liquids and Its Impact on Dual‐Plating Zinc Bromine Batteries

Advanced Science, EarlyView.
This study elucidates mass transport dynamics within polybromide ionic liquids in dual‐plating zinc–bromine batteries using operando impedance spectroscopy. The findings reveal that sluggish polybromide transport during dissolution contrasts with rapid bromide transport during charging.
Sung Il Kim, Kyungjae Shin, Heejung Kang, Seok Hee Han, Hee‐Tak Kim, Taek Dong Chung   +5 more
wiley   +1 more source

Impact of Anode to Cathode Crossover in Lithium-metal Batteries With High-Nickel Cathodes. [PDF]

Adv Mater
Guo Z, Dolocan A, Manthiram A.
europepmc   +1 more source

Large Room Temperature Anomalous Nernst Effect Coupled with Topological Nernst Effect from Incommensurate Spin Structure in a Kagome Antiferromagnet

Advanced Science, EarlyView.
This study demonstrates that ErMn₆Sn₆, a kagome antiferromagnet hosting incommensurate spin textures, sustains finite scalar spin chirality that drives topological states. The anomalous Nernst effect (ANE) originates from the strong Berry curvature of Chern‐gapped Dirac fermions, while the topological Nernst effect (TNE) arises from emergent fields ...
Jiajun Ma, Jiaxing Liao, Yazhou Li, Yuwei Zhang, Jialu Wang, Jinke Bao, Yan Sun, Shuang Jia, Yuke Li   +8 more
wiley   +1 more source

Common variation in meiosis genes shapes human recombination and aneuploidy. [PDF]

Nature
Carioscia SA, Biddanda A, Starostik MR, Tang X, Hoffmann ER, Demko ZP, McCoy RC.   +6 more
europepmc   +1 more source

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Atomically tweaking spin-crossover cooperativity to augment molecular memory density. [PDF]

Nat Commun
Liu J, Bai Y, Xu Z, Chen Q, Pan J, Lin Y, Hu T, Deng H, Gao Y, Huang L, Wang Y, Wu K.   +11 more
europepmc   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

Advanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang, Wen Zhou, Haotian Xue, Wenjun Xue, Guangping Gao, Bing Zhu, Hongyuan Song, Qingqiang Xu, Jing Zhao, Wei Shen   +9 more
wiley   +1 more source

Effects of protein sources at sahur on anaerobic power and strength during Ramadan in combat sport athletes: A single blind, randomized, placebo-controlled, counterbalanced crossover study design. [PDF]

PLoS One
Demirli A, Ulupınar S, Işım AT, Kesler A, Terzi M, Gençoğlu C, Özbay S, Ionel M, Ouergui I, Ardigò LP.   +9 more
europepmc   +1 more source