Results 11 to 20 of about 182,217 (266)
Considerations for crossover design in clinical study [PDF]
Korean Journal of Anesthesiology, 2021 This article introduces a crossover design that is often used in clinical studies, with the advantage of comparing treatment effects within one study subject. In particular, the advantages and disadvantages of the two-period, two-sequence crossover design (2 × 2 or AB/BA crossover design), which is widely used in clinical practice, are identified, and
Chi-Yeon Lim, Junyong In
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Increase of 4-Hydroxybenzoic, a Bioactive Phenolic Compound, after an Organic Intervention Diet
Antioxidants, 2019 Consumption of organic products is increasing yearly due to perceived health-promoting qualities. Several studies have shown higher amounts of phytochemicals such as polyphenols and carotenoids in foods produced by this type of agriculture than in ...
Sara Hurtado-Barroso +5 more
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Journal of Nutritional Science, 2022 Coenzyme Q10 (CoQ10), a lipid involved in ATP synthesis, exhibits very limited oral absorption, and its endogenous production decreases with ageing and with the occurrence of oxidative stress.
Sandrine Beaulieu +2 more
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BMC Medical Research Methodology, 2021 Background Case-crossover studies have been widely used in various fields including pharmacoepidemiology. Vines and Farrington indicated in 2001 that when within-subject exposure dependency exists, conditional logistic regression can be biased.
Kiyoshi Kubota +5 more
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A novel crossover operator for genetic algorithm: Stas crossover [PDF]
Decision Science Letters, 2023 The genetic algorithm (GA) is a natural selection-inspired optimization algorithm. It is a population-based search algorithm that utilizes the concept of survival of the fittest. This study creates a new crossover operator called “Stas Crossover”
Ratchadakorn Poohoi +2 more
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The use of baseline covariates in crossover studies [PDF]
Biostatistics, 2009 It is our experience that in many settings, crossover trials that have within-period baseline measurements are analyzed wrongly. A "conventional" analysis of covariance in this setting uses each baseline as a covariate for the following outcome variable in the same period but not for any other outcome.
Kenward, Michael G., Roger, James H.
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Annals of Medicine, 2023 Background Dexmedetomidine enhances the quality and duration of lidocaine intravenous regional anaesthesia (IVRA). However, the two administration routes have not been directly compared regarding effects on tourniquet tolerance time with lidocaine IVRA ...
Xincheng Liao +5 more
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International Journal of COPD, 2021 Rain Jõgi,1 Leena Mattila,2 Mikko Vahteristo,3 Aino Takala,2 Satu Lähelmä,4 Ville A Vartiainen,2 Ari Lindqvist5 1Tartu University Hospital, Lung Clinic, Tartu, Estonia; 2Medical Affairs, Orion Corporation, Espoo, Finland; 3Research Unit ...
Jõgi R +6 more
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Neurology and Therapy, 2023 Introduction The prevalence of neurological disorders is high among the Mexican population. Clonazepam is primarily indicated to treat panic disorders, certain kinds of epilepsy such as status epilepticus, childhood motor seizures (petit mal absence ...
Luis Genis-Najera +1 more
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Sexual Medicine, 2021 : Introduction: Phosphodiesterase 5 inhibitors are the predominant treatment option for erectile dysfunction. Aim: This study evaluates the efficacy and safety of sildenafil orally disintegrating strips for the treatment of erectile dysfunction. Methods:
Premsant Sangkum, MD +7 more
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