ABSTRACT Tuvusertib is an investigational, orally administered inhibitor of ATR protein kinase, currently in Phase II clinical development. Here, we present an integrated nonclinical and clinical assessment of the effect of tuvusertib on QTc interval.
Jatinder Kaur Mukker +15 more
wiley +1 more source
Transgressivity in Key Functional Traits Rather Than Phenotypic Plasticity Promotes Stress Tolerance in A Hybrid Cordgrass [PDF]
Hybridization might promote offspring fitness via a greater tolerance to environmental stressors due to heterosis and higher levels of phenotypic plasticity.
Castillo Segura, Jesús Manuel +3 more
core +1 more source
Pathways to increasing adolescent physical activity and wellbeing: A mediation analysis of intervention components designed using a participatory approach [PDF]
We assessed which intervention components were associated with change in moderate-to-vigorous physical activity (MVPA) and wellbeing through proposed psychosocial mediators.
Brown, Helen Elizabeth +7 more
core +2 more sources
Abstract This review examines the role of open citations in fostering transparency, reproducibility, and accessibility in scholarly communication. Through a critical synthesis of diverse sources—articles, proceedings, presentations, datasets, and blog posts—it explores the motivations behind citing, the evolving meanings of citations, and key ...
Zehra Taşkın
wiley +1 more source
Exploring Students’ Perceptions of their Experiences in a Social Justice Living–Learning Community [PDF]
Contemporary higher education leaders continue to deem the development of civic-minded graduates as among the primary goals of postsecondary education (Astin, 1996Astin, H. S. (1996). Leadership for social change. About Campus, 1(3), 4–10.
Armstrong, Megan +2 more
core +1 more source
IFNα and IFNγ Impede Marek’s Disease Progression [PDF]
Marek’s disease virus (MDV) is an alphaherpesvirus that causes Marek’s disease, a malignant lymphoproliferative disease of domestic chickens. While MDV vaccines protect animals from clinical disease, they do not provide sterilizing immunity and allow ...
Bertzbach, Luca D. +6 more
core +1 more source
The Effect of a Maternal Mediterranean Diet in Pregnancy on Insulin Resistance is Moderated by Maternal Negative Affect. [PDF]
There is inconsistent evidence that healthy dietary interventions can effectively mitigate the risk of adverse outcomes associated with elevated insulin resistance in pregnancy, suggesting that other moderating factors may be at play.
Buss, Claudia +3 more
core +1 more source
Bringing Citations and Usage Metrics Together to Make Data Count
Over the last years, many organizations have been working on infrastructure to facilitate sharing and reuse of research data. This means that researchers now have ways of making their data available, but not necessarily incentives to do so.
Helena Cousijn +4 more
doaj +1 more source
Where Are the Children in Tourism Empirical Research?
ABSTRACT This research note offers an updated review of Poria and Timothy's (2014) call to better integrate children into tourism research. It critically examines the empirical literature on children in tourism, focusing on how children are represented, studied, and valued within the field.
Hugues Seraphin, Damien Chaney
wiley +1 more source
In Vitro Consequences of Electronic-Cigarette Flavoring Exposure on the Immature Lung. [PDF]
Background: The developing lung is uniquely susceptible and may be at increased risk of injury with exposure to e-cigarette constituents. We hypothesize that cellular toxicity and airway and vascular responses with exposure to flavored refill solutions ...
Berkelhamer, Sara +5 more
core +2 more sources

