Results 31 to 40 of about 1,354 (165)

Biochemical, Pharmacological, and Structural Characterization of New Basic PLA2 Bbil‐TX from Bothriopsis bilineata Snake Venom

open access: yesBioMed Research International, Volume 2013, Issue 1, 2013., 2013
Bbil‐TX, a PLA2, was purified from Bothriopsis bilineata snake venom after only one chromatographic step using RP‐HPLC on μ‐Bondapak C‐18 column. A molecular mass of 14243.8 Da was confirmed by Q‐Tof Ultima API ESI/MS (TOF MS mode) mass spectrometry. The partial protein sequence obtained was then submitted to BLASTp, with the search restricted to PLA2 ...
Victor Corasolla Carregari   +7 more
wiley   +1 more source

Assay of phospholipases A2 and their inhibitors by kinetic analysis in the scooting mode

open access: yesMediators of Inflammation, Volume 1, Issue 2, Page 85-100, 1992., 1992
Several cellular processes are regulated by interfacial catalysis on biomembrane surfaces. Phospholipases A2 (PLA2) are interesting not only as prototypes for interfacial catalysis, but also because they mobilize precursors for the biosynthesis of eicosanoids and platelet activating factor, and these agents ultimately control a wide range of secretory ...
Mahendra Kumar Jain   +3 more
wiley   +1 more source

Medicinal and ethnoveterinary remedies of hunters in Trinidad [PDF]

open access: yes, 2001
BACKGROUND: Ethnomedicines are used by hunters for themselves and their hunting dogs in Trinidad. Plants are used for snakebites, scorpion stings, for injuries and mange of dogs and to facilitate hunting success.
A Borges   +137 more
core   +3 more sources

Bacterial Adaptation to Venom in Snakes and Arachnida [PDF]

open access: yes, 2022
Animal venoms are considered sterile sources of antimicrobial compounds with strong membrane-disrupting activity against multidrug-resistant bacteria. However, venomous bite wound infections are common in developing nations.
Barlow, Axel   +37 more
core   +1 more source

Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop [PDF]

open access: yes, 2011
Background Envenomation by crotaline snakes (rattlesnake, cottonmouth, copperhead) is a complex, potentially lethal condition affecting thousands of people in the United States each year.
A Habib   +100 more
core   +5 more sources

Epidemiology and characteristics of coral snake bites reported to the National Poison Data System (2006‒2022)

open access: yesJournal of the American College of Emergency Physicians Open, Volume 5, Issue 5, October 2024.
Abstract Objectives North American coral snake envenomations can result in life‐threatening neurotoxicity. Their bites are relatively rare, making large studies difficult. Using the National Poison Data System (NPDS), we sought to investigate the epidemiological trends and clinical outcomes associated with North American coral snake bites over a 17 ...
Mary E. Velagapudi   +4 more
wiley   +1 more source

The effects of hyperbaric oxygen therapy on snake‐bite‐associated wounds in dogs

open access: yesJournal of Veterinary Emergency and Critical Care, Volume 34, Issue 3, Page 211-221, May/June 2024.
Abstract Objective To assess the effect of hyperbaric oxygen therapy (HBOT) on Crotalinae envenomation‐induced wound swelling and severity and pain in dogs, and to describe the safety and complications of HBOT. Design Prospective, randomized, controlled, blinded study (2017–2021).
Shelly Olin   +9 more
wiley   +1 more source

In vitro antimicrobial activity of natural toxins and animal venoms tested against Burkholderia pseudomallei [PDF]

open access: yes, 2006
BACKGROUND: Burkholderia pseudomallei are the causative agent of melioidosis. Increasing resistance of the disease to antibiotics is a severe problem in treatment regime and has led to intensification of the search for new drugs.
A Leelarasamee   +51 more
core   +3 more sources

Interactions of small molecule inhibitors with secreted phospholipase A2: A review of the structural data

open access: yesChemical Biology &Drug Design, Volume 103, Issue 2, February 2024.
Due to their roles in inflammation, the sPLA2 enzymes are of much medicinal interest. sPLA2 inhibitors have been developed for the treatment of inflammatory and other conditions such as cardiovascular disease, arteriosclerosis and rheumatoid arthritis.
Chantalle Crous   +2 more
wiley   +1 more source

5\u27-Nucleotidase and Thrombin-Like Activities of Selected Crotalid Venoms [PDF]

open access: yes, 1995
Thrombin-like activities were not observed inCrotalus basiliscus, C. molossus and C. scutulatus scutulatus crude venoms. 5\u27-Nucleotidase specific activities of 0.863, 0.273 and 5.520 units/mg of crude venom protein were observed inC.
Johnson, Bob D.   +2 more
core   +3 more sources

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