Results 21 to 30 of about 1,310 (165)

Low-level laser therapy decreases local effects induced by myotoxins isolated from Bothrops jararacussu snake venom [PDF]

open access: yes, 2010
The prominent myotoxic effects induced by Bothrops jararacussu crude venom are due, in part, to its polycationic myotoxins, BthTX-I and BthTX-II. Both myotoxins have a phospholipase A2 structure: BthTX-II is an active enzyme Asp-49 PLA2, while BthTX-I is
BARBOSA, AM   +6 more
core   +2 more sources

In Silico Analysis of Gene Expression Network Components Underlying Pigmentation Phenotypes in the Python Identified Evolutionarily Conserved Clusters of Transcription Factor Binding Sites

open access: yesAdvances in Bioinformatics, Volume 2016, Issue 1, 2016., 2016
Color variation provides the opportunity to investigate the genetic basis of evolution and selection. Reptiles are less studied than mammals. Comparative genomics approaches allow for knowledge gained in one species to be leveraged for use in another species. We describe a comparative vertebrate analysis of conserved regulatory modules in pythons aimed
Kristopher J. L. Irizarry   +2 more
wiley   +1 more source

Clinical and biochemical changes in 53 Swedish dogs bitten by the European adder - Vipera berus [PDF]

open access: yes, 2010
Background Every year many dogs in Sweden are bitten by Vipera berus, the only venomous viper in Sweden. This prospective study investigated clinical signs, some biochemical parameters, treatment, and progress of disease after snakebite in 53 dogs ...
Jessica Berger Lervik   +24 more
core   +1 more source

Rattlesnake Envenomation in Three Dairy Goats

open access: yesCase Reports in Veterinary Medicine, Volume 2015, Issue 1, 2015., 2015
Cases of rattlesnake envenomation in dairy goats are lacking. These cases present three dairy goats presented to a veterinary referral hospital for envenomation of Northern Pacific Rattlesnake (Crotalus oreganus). Treatments and clinical characteristics reported are similar to those for llamas, alpacas, and horses.
Joseph Smith   +3 more
wiley   +1 more source

Antitumoral Activity of Snake Venom Proteins: New Trends in Cancer Therapy

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
For more than half a century, cytotoxic agents have been investigated as a possible treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues and cell cultures, both normal and tumoral. Snake venoms show the highest cytotoxic potential, since ophidian accidents cause a large amount of tissue damage, suggesting a ...
Leonardo A. Calderon   +14 more
wiley   +1 more source

Ethnopharmacological Significance of Eclipta alba (L.) Hassk. (Asteraceae)

open access: yesInternational Scholarly Research Notices, Volume 2014, Issue 1, 2014., 2014
Eclipta alba can be found growing wild in fallow lands of Bangladesh where it is considered as a weed by farmers. Traditional medicinal systems of the Indian subcontinent countries as well as tribal practitioners consider the plant to have diverse medicinal values and use it commonly for treatment of gastrointestinal disorders, respiratory tract ...
Rownak Jahan   +4 more
wiley   +1 more source

Biochemical, Pharmacological, and Structural Characterization of New Basic PLA2 Bbil‐TX from Bothriopsis bilineata Snake Venom

open access: yesBioMed Research International, Volume 2013, Issue 1, 2013., 2013
Bbil‐TX, a PLA2, was purified from Bothriopsis bilineata snake venom after only one chromatographic step using RP‐HPLC on μ‐Bondapak C‐18 column. A molecular mass of 14243.8 Da was confirmed by Q‐Tof Ultima API ESI/MS (TOF MS mode) mass spectrometry. The partial protein sequence obtained was then submitted to BLASTp, with the search restricted to PLA2 ...
Victor Corasolla Carregari   +7 more
wiley   +1 more source

Antiophidian properties of plant extracts against Lachesis muta venom [PDF]

open access: yes, 2010
Snakebites comprise a serious health problem in several countries due to their global incidence, which exceeds 2.5 million per year, and the elevated number of victim fatalities.
COSTA, TR   +7 more
core   +2 more sources

Snake Venom: Any Clue for Antibiotics and CAM?

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2, Issue 1, Page 39-47, 2005., 2005
Lately several naturally occurring peptides presenting antimicrobial activity have been described in the literature. However, snake venoms, which are an enormous source of peptides, have not been fully explored for searching such molecules. The aim of this work is to review the basis of antimicrobial mechanisms revealing snake venom as a feasible ...
Deivy Clementino de Lima   +8 more
wiley   +1 more source

Assay of phospholipases A2 and their inhibitors by kinetic analysis in the scooting mode

open access: yesMediators of Inflammation, Volume 1, Issue 2, Page 85-100, 1992., 1992
Several cellular processes are regulated by interfacial catalysis on biomembrane surfaces. Phospholipases A2 (PLA2) are interesting not only as prototypes for interfacial catalysis, but also because they mobilize precursors for the biosynthesis of eicosanoids and platelet activating factor, and these agents ultimately control a wide range of secretory ...
Mahendra Kumar Jain   +3 more
wiley   +1 more source

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