Results 1 to 10 of about 913 (116)
Crotoxin B: Heterologous Expression, Protein Folding, Immunogenic Properties, and Irregular Presence in Crotalid Venoms [PDF]
Toxins, 2022 Crotoxin complex CA/CB and crotamine are the main toxins associated with Crotalus envenomation besides the enzymatic activities of phospholipases (PLA2) and proteases.
Miguel Angel Mejía-Sánchez +5 more
doaj +4 more sources
Effect of suramin on myotoxicity of some crotalid snake venoms [PDF]
Brazilian Journal of Medical and Biological Research, 2002 We investigated the protective effect of suramin, an enzyme inhibitor and an uncoupler of G protein from receptors, on the myotoxic activity in mice of different crotalid snake venoms (A.c. laticinctus, C.v. viridis, C.d. terrificus, B.
Paulo A Melo
exaly +6 more sources
Neutralization of edema, hemorrhage and myonecrosis induced by North American crotalid venoms in simulated first-aid treatments [PDF]
Toxicon, 1999 Venoms of the broad-banded copperhead (Agkistrodon contortrix laticinctus, ACL) and the prairie rattlesnake (Crotalus viridis viridis, CVV), like other crotalid venoms, cause severe local tissue damage such as edema, hemorrhage and myonecrosis. Antivenom therapy is not very effective in neutralizing this local tissue damage, and such observations ...
Jason P Evans +2 more
exaly +3 more sources
Toxicon, 2003 In 1984, the first venom phospholipase A2 (PLA2) with a lysine substituting for the highly conserved aspartate 49 was discovered, in the North American crotalid snake Agkistrodon p. piscivorus [J. Biol. Chem. 259 (1984) 13839]. Ten years later, the first mapping of a 'toxic region' on a Lys49 PLA2 was reported, in Bothrops asper myotoxin II [J.
Bruno Lomonte, Yamileth Angulo
exaly +5 more sources
Revista da Sociedade Brasileira de Medicina Tropical, 2022 Snake toxins are widely studied owing to their importance in snakebite accidents, a serious public health issue in tropical countries, and their broad therapeutic potential.
Brunna Fernanda Arraez Alves +1 more
doaj +1 more source
A novel activity on thymocytes cells exerted by the rattlesnake (Crotalus durissus cumanensis) venom
Biomédica: revista del Instituto Nacional de Salud, 2021 Introduction: The thymus is active mainly during the neonatal and pre-adolescent periods. Objective: To test naïve thymocytes proliferation and monocytes stimulation. Materials and methods: We collected fresh thymus tissue from neonate mice after surgery.
María M. Pulido-Méndez +2 more
doaj +1 more source
Toxins, 2021 Phospholipases A2s (PLA2s) constitute one of the major protein groups present in the venoms of viperid and crotalid snakes. Snake venom PLA2s (svPLA2s) exhibit a remarkable functional diversity, as they have been described to induce a myriad of toxic ...
Vanessa Moreira +5 more
doaj +1 more source
Serum proteins and electrophoretic profile in horses undergoing crotalid venom hyperimmunization
Journal of Equine Science, 2022 Indisputably, the use of antivenoms for the treatment of snakebite envenoming is beneficial for the victims. However, there are few studies addressing the effect of long-term hyperimmunization in inoculated horses. It is known that the injection of snake venoms and adjuvants leads to local and systemic reactions in horses, but little is known about the
RAMOS, Monique Gonçalves S. Novelino +6 more
openaire +2 more sources
Case Reports in Veterinary Medicine, Volume 2020, Issue 1, 2020., 2020 A 0.34 kg adult female Massasauga rattlesnake (Sistrurus catenatus) was presented for evaluation of a subcutaneous mass affecting the ventral scales. The mass was diagnosed as a sarcoma via punch biopsy with no evidence of metastasis on diagnostic imaging. Surgical margins of 1‐2 cm were planned to achieve complete excision of the neoplasm. A technique
Kate E. Archibald +4 more
wiley +1 more source
Polyamines as Snake Toxins and Their Probable Pharmacological Functions in Envenomation
Toxins, 2016 While decades of research have focused on snake venom proteins, far less attention has been paid to small organic venom constituents. Using mostly pooled samples, we surveyed 31 venoms (six elapid, six viperid, and 19 crotalid) for spermine, spermidine ...
Steven D. Aird +3 more
doaj +1 more source