Results 31 to 40 of about 10,138 (150)

Bothrops atrox and Bothrops lanceolatus Venoms In Vitro Investigation: Composition, Procoagulant Effects, Co-Factor Dependency, and Correction Using Antivenoms

, 2023
Bothrops venoms are rich in enzymes acting on platelets and coagulation. This action is dependent on two major co-factors, i.e., calcium and phospholipids, while antivenoms variably neutralize venom-related coagulopathy effects.
Rabah Gahoual, Anne-Laure Dupart, Sébastien Larréché, Virginie Siguret, Georges Jourdi, Pascale Gaussem, Jean-Philippe Chippaux, Aurore Bousquet, Christilla Bachelot-Loza, Lucie Chevillard, Bruno Mégarbane   +10 more
core   +1 more source

The effects of hyperbaric oxygen therapy on snake‐bite‐associated wounds in dogs

Journal of Veterinary Emergency and Critical Care, Volume 34, Issue 3, Page 211-221, May/June 2024.
Abstract Objective To assess the effect of hyperbaric oxygen therapy (HBOT) on Crotalinae envenomation‐induced wound swelling and severity and pain in dogs, and to describe the safety and complications of HBOT. Design Prospective, randomized, controlled, blinded study (2017–2021).
Shelly Olin, Julie Schildt, Michael Lane, Adesola Odunayo, Cary Springer, Dana Call, Selene Jones, Dennis Geiser, Daryl Millis, Marti Drum   +9 more
wiley   +1 more source

Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors [PDF]

, 2013
Venoms from cone snails (Conidae) have been extensively studied during the last decades, but those from other members of the suborder Toxoglossa, such as of Terebridae and Turridae superfamilies attracted less interest so far. Here, we report the effects
Wunder, C., Peigneur, S., Silke Kauferstein, Melaun, Christian, Annette Nicke, Nicke, Annette, Dietrich Mebs, Christian Melaun, Peigneur, Steve, Kauferstein, S., Kauferstein, Silke, Wunder, Cora, Kendel, Y., Mebs, D., Kurz, A., Steve Peigneur, Tytgat, Jan, Melaun, C., Kendel, Yvonne, Kurz, Alexander, Mebs, Dietrich, Yvonne Kendel, Jan Tytgat, Cora Wunder, Alexander Kurz, Nicke, A., Tytgat, J.   +26 more
core   +1 more source

Varespladib (LY315920) and Methyl Varespladib (LY333013) Abrogate or Delay Lethality Induced by Presynaptically Acting Neurotoxic Snake Venoms [PDF]

, 2020
The phospholipase A2 (PLA2) inhibitor Varespladib (LY315920) and its orally bioavailable prodrug, methyl-Varespladib (LY333013) inhibit PLA2 activity of a wide variety of snake venoms.
Bruno Lomonte, Williams, David J., Lewin, Matthew R., Matthew R. Lewin, José María Gutiérrez, Lomonte, Bruno, Gutiérrez, José María, David. J. Williams   +7 more
core   +1 more source

Interactions of small molecule inhibitors with secreted phospholipase A2: A review of the structural data

Chemical Biology &Drug Design, Volume 103, Issue 2, February 2024.
Due to their roles in inflammation, the sPLA2 enzymes are of much medicinal interest. sPLA2 inhibitors have been developed for the treatment of inflammatory and other conditions such as cardiovascular disease, arteriosclerosis and rheumatoid arthritis.
Chantalle Crous, Anél Petzer, Jacobus P. Petzer   +2 more
wiley   +1 more source

Differences between Two Groups of Burmese Vipers (Viperidae: Azemiops) in the Proteomic Profiles, Immunoreactivity and Biochemical Functions of Their Venoms

, 2022
Two recently revised Azemiops snakes with apparent differences in their external appearances and skeletal morphologies but unclear genetic boundaries have been proposed. Some researchers have refrained from using the newly proposed taxonomy because these
Gao, Jian-Fang, Zhao, Hong-Yan, Wen, Lin, Hong-Yan Zhao, Jian-Fang Gao, Zheng, Si-Rui, Lin Wen, Ji, Xiang, Yan Sun, Sun, Yan, Si-Rui Zheng, Xiang Ji   +11 more
core   +1 more source

Inhibition of toxic activities of Bothrops asper venom and other crotalid snake venoms by a novel neutralizing mixture.

Toxicology and applied pharmacology, 1998
/[DHR-5544-6-00-1064-00]/AID/
Borkow, Gadi, Gutiérrez, José María, Ovadia, Michael   +2 more
openaire   +4 more sources

Screening Snake Venoms for Toxicity to Tetrahymena Pyriformis Revealed Anti-Protozoan Activity of Cobra Cytotoxins

, 2020
Snake venoms possess lethal activities against different organisms, ranging from bacteria to higher vertebrates. Several venoms were shown to be active against protozoa, however, data about the anti-protozoan activity of cobra and viper venoms are very ...
Vladislav Starkov, Elena Kruykova, Victor Tsetlin, Elena Cheremnykh, Olga Kuleshina, Yuri Utkin, Alexey Osipov, Leonid Kozlov, Rustam Ziganshin, Tatyana Andreeva   +9 more
core   +1 more source

Snake C-Type Lectins Potentially Contribute to the Prey Immobilization in Protobothrops mucrosquamatus and Trimeresurus stejnegeri Venoms

, 2020
Snake venoms contain components selected to immobilize prey. The venoms from Elapidae mainly contain neurotoxins, which are critical for rapid prey paralysis, while the venoms from Viperidae and Colubridae may contain fewer neurotoxins but are likely to ...
Hao Li, James Mwangi, Qiumin Lu, Chengbo Long, Chuanbin Shen, Ming Liu, Jiameng Li, Ren Lai, Huiwen Tian, Runjia Xu   +9 more
core   +1 more source

Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles

, 2020
Latest advancement of omics technologies allows in-depth characterization of venom compositions. In the present work we present a proteomic study of two snake venoms of the genus Naja i.e., Naja naja (black cobra) and Naja oxiana (brown cobra) of ...
Zia Mughal, Syed Abid Ali, Aisha Manuwar, Andreas Böhmert, Anwar Ullah, Ahmed Akrem, Benjamin Dreyer, Hartmut Schlüter, Christian Betzel   +8 more
core   +1 more source