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Recent Advances in the Cellular and Developmental Biology of Phospholipases in Plants
Phospholipases (PLs) are lipid-hydrolyzing enzymes known to have diverse signaling roles during plant abiotic and biotic stress responses. They catalyze lipid remodeling, which is required to generate rapid responses of plants to environmental cues ...
Tomáš Takac +2 more
exaly +3 more sources
Search for and functional annotation of multi-domain PLA2 family proteins in flatworms
The phospholipase A2 (PLA2) is a superfamily of hydrolases that catalyze the hydrolysis of phospholipids and play a key role in many molecular processes in the cells and the organism as a whole.
M. E. Bocharnikova +2 more
doaj +2 more sources
Background: Phospholipases are enzymes with the capacity to hydrolyze membrane lipids and have been characterized in several allergenic sources, such as hymenoptera species.
Yuliana Emiliani +4 more
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Phospholipases in Gliomas: Current Knowledge and Future Perspectives from Bench to Bedside
Phospholipases are essential intermediaries that work as hydrolyzing enzymes of phospholipids (PLs), which represent the most abundant species contributing to the biological membranes of nervous cells of the healthy human brain.
Maria Vittoria Marvi +15 more
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Phospholipases A and Lysophospholipases in protozoan parasites
Phospholipases (PLs) and Lysophospholipases (LysoPLs) are a diverse group of esterases responsible for phospholipid or lysophospholipid hydrolysis. They are involved in several biological processes, including lipid catabolism, modulation of the immune ...
Perrine Hervé +3 more
doaj +1 more source
Phospholipases A in Trypanosomatids [PDF]
Phospholipases are a complex and important group of enzymes widespread in nature, that play crucial roles in diverse biochemical processes and are classified as A1, A2, C, and D. Phospholipases A1and A2activities have been linked to pathogenesis in various microorganisms, and particularly in pathogenic protozoa they have been implicated in cell ...
María Laura Belaunzarán +2 more
openaire +3 more sources
Human phospholipases A2: a functional and evolutionary analysis
Phospholipases A2 (PLA2) are capable of hydrolyzing the sn-2 position of glycerophospholipids to release fatty acids and lysophospholipids. The PLA2 superfamily enzymes are widespread and present in most mammalian cells and tissues, regulating metabolism,
I. I. Turnaev +2 more
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Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in ...
Richmond, Gregory S., Smith, Terry K.
openaire +2 more sources
Interface of Phospholipase Activity, Immune Cell Function, and Atherosclerosis
Phospholipases are a family of lipid-altering enzymes that can either reduce or increase bioactive lipid levels. Bioactive lipids elicit signaling responses, activate transcription factors, promote G-coupled-protein activity, and modulate membrane ...
Robert M. Schilke +3 more
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Signal-activated phospholipase regulation of leukocyte chemotaxis
Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
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