Results 21 to 30 of about 96,105,277 (199)

A novel lipase with dual localisation in Trypanosoma brucei

open access: yesScientific Reports, 2022
Phospholipases are esterases involved in lipid catabolism. In pathogenic micro-organisms (bacteria, fungi, parasites) they often play a critical role in virulence and pathogenicity. A few phospholipases (PL) have been characterised so far at the gene and
S.G. Monic   +7 more
doaj   +1 more source

Bacterial Type 6 Secreted Phospholipases Play Family Feud [PDF]

open access: yes, 2013
Secreted bacterial phospholipases play many important roles in host-pathogen interactions. In a recent study, Russell et al. (2013) revealed a new role for highly conserved proteobacterial phospholipases in bacterium-bacterium ...
Hammond, John H., Hogan, Deborah A.
core   +1 more source

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

open access: yesToxins, 2021
A global strategy, under the coordination of the World Health Organization, is being unfolded to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure safe and effective treatments.
José María Gutiérrez   +6 more
doaj   +1 more source

Phospholipase C [PDF]

open access: yes, 2019
Phospholipase C (PLC) family members constitute a family of diverse enzymes. Thirteen different family members have been cloned. These family members have unique structures that mediate various functions. Although PLC family members all appear to signal through the bi-products of cleaving phospholipids, it is clear that each family member, and at times
Colin A, Bill, Charlotte M, Vines
openaire   +2 more sources

Phospholipases: From Structure to Biological Function

open access: yes, 2021
Phospholipases are enzymes that cleave ester bonds within phospholipids [...]Work in the authors’ laboratories was funded by the Spanish Ministry of Science and Innovation, grant numbers SAF2016-80883-R and PID2019-105989RB-I00. CIBERDEM is an initiative
Jesús Balsinde   +3 more
core   +1 more source

Differentiation-dependent regulation of secreted phospholipases A2 in murine epidermis [PDF]

open access: yes, 2003
The action of secreted phospholipases A2 in skin is thought to be essential for epidermal barrier homeostasis. The incomplete knowledge of presence and functions of the novel secreted phospholipase A2 subtypes in skin prompted us to explore their ...
Gurrieri, Silvia   +19 more
core   +1 more source

The emerging roles of PAF acetylhydrolase

open access: yesJournal of Lipid Research, 2009
Platelet-activating factor (PAF), a phospholipid autacoid with potent effects throughout the innate immune system, is selectively degraded by two small families of PAF acetylhydrolases (PAF-AHs).
Thomas M. McIntyre   +2 more
doaj   +1 more source

PTEN regulates phospholipase D and phospholipase C [PDF]

open access: yesHuman Molecular Genetics, 2007
PTEN is an ubiquitously expressed tumor suppressor which plays a prominent role in the pathogenesis of many types of sporadic solid tumors, including breast cancer, as well as hematologic malignancies. Germline PTEN mutations cause 85% of Cowden syndrome (CS), characterized by a high risk of breast and thyroid cancers, and 65% of Bannayan-Riley ...
Christopher A, Alvarez-Breckenridge   +2 more
openaire   +2 more sources

Stalling autophagy: a new function for Listeria phospholipases

open access: yesMicrobial Cell, 2014
Listeria monocytogenes is a Gram-positive bacterial pathogen that induces its own uptake in non-phagocytic cells. Following invasion, Listeria escapes from the entry vacuole through the secretion of a pore-forming toxin, listeriolysin O (LLO) that acts ...
Ivan Tattoli   +3 more
doaj   +1 more source

Modification of lecithin-based emulsions with phospholipases

open access: yesCyTA - Journal of Food, 2020
Phospholipases have been used in different food processes, but mainly on degumming vegetable oils. More recently, the use of these enzymes has been extended to the manufacture of bread and dairy products. However, little is known on phospholipases effect
Dely Rubí Chávez-Garay   +6 more
doaj   +1 more source

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