Results 1 to 10 of about 2,732,817 (216)

Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease. [PDF]

PLoS ONE, 2010
Reduced brain levels of docosahexaenoic acid (C22:6n-3), a neurotrophic and neuroprotective fatty acid, may contribute to cognitive decline in Alzheimer's disease.
Giuseppe Astarita, Kwang-Mook Jung, Nicole C Berchtold, Vinh Q Nguyen, Daniel L Gillen, Elizabeth Head, Carl W Cotman, Daniele Piomelli   +7 more
doaj   +5 more sources

Effects of Docosahexaenoic Acid on Prostate Cancer [PDF]

Journal of Xenobiotics
The polyunsaturated fatty acids of the omega-3 class have been widely investigated due to their antitumor properties, including in prostate cancer (PCa).
Guilherme Henrique Tamarindo, Gustavo Matheus Amaro, Alana Della Torre da Silva, Rejane Maira Góes   +3 more
doaj   +2 more sources

Molecular dynamic of omega-3 compounds as an anti-obesity agent into GPR-120 receptor [PDF]

Pharmacia, 2023
Obesity is a cause of comorbid diseases such as type 2 diabetes mellitus, dyslipidemia, hypertension which is based on low-level chronic inflammation. The GPR-120 receptor plays a role in insulin sensitization which is related to diabetes mellitus which ...
Ida Musfiroh, Ginna Megawati, Dewi Marhaeni Diah Herawati, Okta Nama Putra, Evi Sylvia Nurrasjid   +4 more
doaj   +3 more sources

Determination of eicosapentaenoic acid and docosahexaenoic acid contents and the oxidation level of fish oil supplements from Bahrain market

Arab Journal of Basic and Applied Sciences, 2023
Eicosapentaenoic acid and docosahexaenoic acid are two types of omega-3 fatty acids that provide numerous health benefits. It is thus important to gain the recommended daily intake of eicosapentaenoic acid and docosahexaenoic acid and compensate for ...
Hawra Abdulhussain, Aysha Khonji, Ayla Alsaloom, Hawra Meshaima, Latifa AlKooheji, Mohammed Aldoseri, Mariam Al-Mannai, Afnan Freije   +7 more
doaj   +1 more source

Antibiofilm Activity of Omega-3 Fatty Acids and Its Influence on the Expression of Biofilm Formation Genes on Staphylococcus aureus

Antibiotics, 2022
Background: Currently, 1–2% of all prosthetic joint surgeries are followed by an infection. These infections cause approximately 4% of deaths in the first year after surgery, while the 5-year mortality rate is up to 21%.
Christopher Spiegel, Stephan Josef Maria Steixner, Débora C. Coraça-Huber   +2 more
doaj   +1 more source

Formulation design and pharmacokinetic evaluation of docosahexaenoic acid containing self-nanoemulsifying drug delivery system for oral administration

Nanomaterials and Nanotechnology, 2020
Docosahexaenoic acid is a omega-3-fatty acid which together with other long-chain omega-3-fatty acid known to have protective effect against various diseases including hypertension, myocardial infarction, Alzheimer disease, and cancers.
Nabil A Alhakamy, Hibah M Aldawsari, Khaled M Hosny, Javed Ahmad, Sohail Akhter, Ahmed K Kammoun, Adel F Alghaith, Hani Z Asfour, Mohammed W Al-Rabia, Shadab Md   +9 more
doaj   +1 more source

Cultivation Method Effect on Schizochytrium sp. Biomass Growth and Docosahexaenoic Acid (DHA) Production with the Use of Waste Glycerol as a Source of Organic Carbon

Energies, 2021
Inexpensive carbon sources offering an alternative to glucose are searched for to reduce costs of docosahexaenoic acid production by microalgae. The use of waste glycerol seems substantiated and prospective in this case.
Natalia Kujawska, Szymon Talbierz, Marcin Dębowski, Joanna Kazimierowicz, Marcin Zieliński   +4 more
doaj   +1 more source

Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. [PDF]

PLoS ONE, 2014
Maresins are a new family of anti-inflammatory and pro-resolving lipid mediators biosynthesized from docosahexaenoic acid (DHA) by macrophages. Here we identified a novel pro-resolving product, 13R,14S-dihydroxy-docosahexaenoic acid (13R,14S-diHDHA ...
Bin Deng, Chin-Wei Wang, Hildur H Arnardottir, Yongsheng Li, Chien-Yee Cindy Cheng, Jesmond Dalli, Charles N Serhan   +6 more
doaj   +1 more source

Docosahexaenoic acid (DHA), essentiality and requirements: why and how to provide supplementation

Grasas y Aceites, 2006
Lipids comprize from 50-60% of the structural matter of the brain and docosahexaenoic acid (C22:6, DHA) is the most  important omega-3 long-chain polyunsaturated fatty acid in the brain phospholipids comprizing 25% of the total fatty acids of the grey ...
Alfonso Valenzuela, B. Julio Sanhueza, Susana Nieto   +2 more
doaj   +1 more source

Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid

Journal of Lipid Research, 1995
The purpose of this study was to determine whether the formation of docosahexaenoic acid in human cells occurs through a pathway that involves 24-carbon n-3 fatty acid intermediates and retroconversion.
S A Moore, E Hurt, E Yoder, H Sprecher, A A Spector   +4 more
doaj   +1 more source