Linking low docosahexaenoic acid intake to Alzheimer’s disease: caution recommended [PDF]
Prospective cohort studies and animal models support the concept that low docosahexaenoic acid intake is implicated in the etiology or progression of Alzheimer’s disease. However, other studies crucial to this relationship are less encouraging.
Cunnane Stephen C. +5 more
doaj +2 more sources
Jia-run Yang, Dong Han, Zheng-xue Qiao, Xue Tian, Dong Qi, Xiao-hui QiuDepartment of Medical Psychology, Public Health Institute of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of ChinaObjectives: Previous randomized ...
Yang JR +5 more
doaj +1 more source
Docosahexaenoic acid: membrane modification and neurotrophic mechanisms
Docosahexaenoic acid (DHA, 22:6n-3) is highly enriched in the brain mainly in membrane phospholipids. Maintenance of a high DHA concentration in brain is essential for proper neuronal function, suggesting a unique requirement of this fatty acid for an ...
Kim Hee-Yong
doaj +2 more sources
Enhancing the accumulation of eicosapentaenoic acid and docosahexaenoic acid in transgenic Camelina through the CRISPR‐Cas9 inactivation of the competing FAE1 pathway [PDF]
Brief Communication Enhancing the accumulation of eicosapentaenoic acid and docosahexaenoic acid in transgenic Camelina through the CRISPR-Cas9 inactivation of the competing FAE1 ...
Han, L. +16 more
core +1 more source
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women [PDF]
Background: We studied the oxidation of an oil rich in docosahexaenoic acid (DHA; DHASCO(R)) in lactating mothers receiving a dietary DHA supplement or a placebo. The results were compared with the oxidation of linoleic acid.
Pohl, A. +4 more
core +1 more source
Breastfeeding, the use of docosahexaenoic acid-fortified formulas in infancy and neuropsychological function in childhood [PDF]
Objective: To investigate the relation between breastfeeding, use of docosahexaenoic acid (DHA)-fortified formula and neuropsychological function in children. Design Prospective cohort study. Setting Southampton, UK.
West, Carolyn +36 more
core +1 more source
Amyloid-beta peptide, oxidative stress and inflammation in Alzheimer’s disease: Potential neuroprotective effects of omega-3 polyunsaturated fatty acids [PDF]
Alzheimer’s disease is the most common form of dementia in the elderly and is a progressive neurodegenerative disorder characterised by a decline in cognitive function and also profound alterations in mood and behaviour. The pathology of the disease is
S. C. Dyall +2 more
core +1 more source
Effect of diet on the rate of depletion of n–3 fatty acids in the retina of the guinea pig
This study has assessed the influence of maternal n–3 long chain polyunsaturated fatty acid supply and dietary manipulation after weaning on the retinal polyunsaturated fatty acid profile.
Harrison S. Weisinger +3 more
doaj +1 more source
Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition. [PDF]
Red blood cell (RBC) n-3 fatty acid status is related to various health outcomes. Accepted biological markers for the fatty acid status determination are RBC phospholipids, phosphatidylcholine, and phosphatidyletholamine.
Hans Demmelmair +11 more
core +2 more sources

