Results 1 to 10 of about 77,099 (297)

Stearidonic acid improves eicosapentaenoic acid status: studies in humans and cultured hepatocytes [PDF]

Frontiers in Nutrition
BackgroundAhiflower oil from the seeds of Buglossoides arvensis is rich in α-linolenic acid (ALA) and stearidonic acid (SDA). ALA and SDA are potential precursor fatty acids for the endogenous synthesis of eicosapentaenoic acid (EPA) and docosahexaenoic ...
Ulrike Seidel, Katharina Eberhardt, Michelle Wiebel, Kai Luersen, Ignacio R. Ipharraguerre, Franziska A. Haegele, Peter Winterhalter, Anja Bosy-Westphal, Nils Helge Schebb, Gerald Rimbach   +9 more
doaj   +2 more sources

Emerging Pathways of Action of Eicosapentaenoic Acid (EPA) [PDF]

JACC: Basic to Translational Science
Deepak L. Bhatt, MD, MPH, MBA, Peter Libby, MD, R. Preston Mason, PhD, MBA   +2 more
doaj   +2 more sources

Eicosapentaenoic acid and oxypurinol in the treatment of muscle wasting in a mouse model of cancer cachexia [PDF]

, 2012
Cancer cachexia is a wasting condition, driven by systemic inflammation and oxidative stress. This study investigated eicosapentaenoic acid (EPA) in combination with oxypurinol as a treatment in a mouse model of cancer cachexia. Mice with cancer cachexia
Hinch, Edward, Lewandowski, Paul A., Martin, Peter, Sullivan-Gunn, Melanie, Vaughan, Vanessa C.   +4 more
core   +18 more sources

Effects of Eicosapentaenoic Acid vs Eicosapentaenoic/Docosahexaenoic Acids on Cardiovascular Mortality: Meta-Analysis of Clinical Trials. [PDF]

JACC Adv
Sheppard JP, Palatnic L, Lakshmanan S, Drago T, Bhogal J, Roy SK, Bhatt DL, Budoff MJ, Nelson JR.   +8 more
europepmc   +2 more sources

Molecular dynamic of omega-3 compounds as an anti-obesity agent into GPR-120 receptor [PDF]

Pharmacia, 2023
Obesity is a cause of comorbid diseases such as type 2 diabetes mellitus, dyslipidemia, hypertension which is based on low-level chronic inflammation. The GPR-120 receptor plays a role in insulin sensitization which is related to diabetes mellitus which ...
Ida Musfiroh, Ginna Megawati, Dewi Marhaeni Diah Herawati, Okta Nama Putra, Evi Sylvia Nurrasjid   +4 more
doaj   +3 more sources

Determination of eicosapentaenoic acid and docosahexaenoic acid contents and the oxidation level of fish oil supplements from Bahrain market

Arab Journal of Basic and Applied Sciences, 2023
Eicosapentaenoic acid and docosahexaenoic acid are two types of omega-3 fatty acids that provide numerous health benefits. It is thus important to gain the recommended daily intake of eicosapentaenoic acid and docosahexaenoic acid and compensate for ...
Hawra Abdulhussain, Aysha Khonji, Ayla Alsaloom, Hawra Meshaima, Latifa AlKooheji, Mohammed Aldoseri, Mariam Al-Mannai, Afnan Freije   +7 more
doaj   +1 more source

Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue [PDF]

, 2020
Statin-related muscle side effects are a constant healthcare problem since patient compliance is dependent on side effects. Statins reduce plasma cholesterol levels and can prevent secondary cardiovascular diseases.
Dittmar, Gunnar, Grieben, Ulrike, Grunwald, Stefanie Anke, Haafke, Stefanie, Jedraszczak, Nicole, Kress, Wolfram, Patone, Giannino, Popp, Oliver, Saar, Kathrin, Spuler, Simone, Steinhagen-Thiessen, Elisabeth   +10 more
core   +1 more source

Differential effects of eicosapentaenoic acid and oleic acid on lipid synthesis and secretion by HepG2 cells.

Journal of Lipid Research, 1991
The effects of eicosapentaenoic acid and oleic acid on lipid synthesis and secretion by HepG2 cells were examined to identify fatty acid specific changes in lipid metabolism that might indicate a basis for the hypolipidemic effect attributed to ...
R Homan, JE Grossman, HJ Pownall
doaj   +1 more source

Effect of EPA and Vitamin C on Superoxide Dismutase, Glutathione Peroxidase, Total Antioxidant Capacity and Malondialdehyde in Type 2 Diabetic Patients

Oman Medical Journal, 2014
Objectives: The aim of this study is to investigate the effect of eicosapentaenoic acid combined with vitamin C in comparison with the pure form of eicosapentaenoic acid on the serum concentration of malondialdehyde, erythrocyte activity of superoxide ...
Mohammad Mehdi Shakouri Mahmoudabadi, Ali Reza Rahbar   +1 more
doaj   +1 more source

Effects of Eicosapentaenoic Acid during In Vitro Maturation of Porcine Oocytes: Hormone Synthesis and Embryonic Developmental Potential

Journal of Animal Reproduction and Biotechnology, 2019
Among fatty acid families, the polyunsaturated fatty acids were demonstrated to be mediators in various reproductive processes as precursor of steroid hormone (via cholesterol) and prostaglandins (via arachidonic acid), and in the last decade, major ...
Kang-Sig Kim, Hum-Dai Park
doaj   +1 more source