Results 11 to 20 of about 35,660 (219)

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Metabolism of n-3 polyunsaturated fatty acids and modification of phospholipids in cultured rabbit aortic smooth muscle cells.

Journal of Lipid Research, 1985
The metabolism of the linolenic acid family (n-3) of fatty acids, e.g., linolenic, eicosapentaenoic, and docosahexaenoic acids, in cultured smooth muscle cells from rabbit aorta was compared to the metabolism of linoleic and arachidonic acids.
N Morisaki, T Kanzaki, Y Fujiyama, I Osawa, K Shirai, N Matsuoka, Y Saito, S Yoshida   +7 more
doaj   +1 more source

Role of EPA in Inflammation: Mechanisms, Effects, and Clinical Relevance

Biomolecules, 2022
Many chronic inflammatory processes are linked with the continuous release of inflammatory mediators and the activation of harmful signal-transduction pathways that are able to facilitate disease progression.
Rosalia Crupi, Salvatore Cuzzocrea
doaj   +1 more source

FISHing for the Miracle of Eicosapentaenoic Acid

New England Journal of Medicine, 2019
Bhatt et al. report in the Journal the results of the Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial (REDUCE-IT), in which 8179 high-risk patients who had elevated triglyceride levels and had been receiving statin therapy were randomly assigned to receive 2 g of icosapent ethyl twice daily or placebo containing mineral oil.1
Kastelein, John J. P., Stroes, Erik S. G.   +1 more
openaire   +2 more sources

A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution

Frontiers in Immunology, 2021
The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros, Ashley E. Shay, Robert Nshimiyimana, David Fichtner, Michael J. Martin, Nicholas Wourms, Charles N. Serhan   +6 more
doaj   +1 more source

Eicosapentaenoic acid reduces hepatic synthesis and secretion of triacylglycerol by decreasing the activity of acyl-coenzyme A:1,2-diacylglycerol acyltransferase

Journal of Lipid Research, 1988
The mechanism for the reduced hepatic production of triacylglycerol in the presence of eicosapentaenoic acid was explored in short-term experiments using cultured parenchymal cells and microsomes from rat liver.
A C Rustan, J O Nossen, E N Christiansen, C A Drevon   +3 more
doaj   +1 more source

Fat deposition of broiler chickens fed a high-fat diet contained Sauropus androgynus leaf extract plus turmeric powder

Journal of the Indonesian Tropical Animal Agriculture, 2019
A factorial design was used to analyzethe influenceofSauropus androgynusleaf extract (SALE) and turmeric powder (TP) on fat deposition in broilers fed high-fat diet.
K. Kususiyah, U. Santoso, Y. Fenita, A. M. H. Putranto, S. Suharyanto   +4 more
doaj   +1 more source

COMPARATIVE LEVELS OF RACHIDONIC ACID AND EICOSAPENTAENOIC ACID IN EGYPTIAN FISH [PDF]

Assiut Veterinary Medical Journal, 1999
Studies were done on the phospholipid fatty acid composition of the most important aquatic animals flesh which represents the freshwater fish and marine fish.
A. Mandour, M.H. Kotkat, Kh. Khilo
doaj   +1 more source

Regulatory effects of individual n-6 and n-3 polyunsaturated fatty acids on LDL transport in the rat

Journal of Lipid Research, 1993
Dietary triglycerides containing predominantly poly-unsaturated fatty acids (PUFAs) are known to reduce plasma total and low density lipoprotein (LDL) cholesterol concentrations relative to triglycerides containing predominantly saturated fatty acids ...
DK Spady
doaj   +1 more source

Modification of spleen phospholipid fatty acid composition by dietary fish oil and by n-3 fatty acid ethyl esters

Journal of Lipid Research, 1993
We have compared the effects of diets containing purified ethyl esters of either eicosapentaenoic acid, docosahexaenoic acid, or a mixture of both of these compounds, with diets containing either purified fish oil or beef tallow on spleen phospholipid ...
DR Robinson, LL Xu, CT Knoell, S Tateno, W Olesiak   +4 more
doaj   +1 more source