Results 11 to 20 of about 77,099 (297)

EICOSAPENTAENOIC ACID IN FAT

The Lancet, 1987
Katan, M.B., van de Bovenkamp, P.
exaly   +9 more sources

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Modification of CaCo-2 cell membrane fatty acid composition by eicosapentaenoic acid and palmitic acid: effect on cholesterol metabolism

Journal of Lipid Research, 1988
Membrane fatty acid composition of CaCo-2 cells was modified by incubating the cells for 8 days in medium containing 100 microM eicosapentaenoic acid or palmitic acid.
S Murthy, E Albright, S N Mathur, F J Field   +3 more
doaj   +1 more source

A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution

Frontiers in Immunology, 2021
The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros, Ashley E. Shay, Robert Nshimiyimana, David Fichtner, Michael J. Martin, Nicholas Wourms, Charles N. Serhan   +6 more
doaj   +1 more source

Effect of Vascepa (icosapent ethyl) on progression of coronary atherosclerosis in patients with elevated triglycerides (200-499 mg/dL) on statin therapy: Rationale and design of the EVAPORATE study. [PDF]

, 2018
Despite reducing progression and promoting regression of coronary atherosclerosis, statin therapy does not fully address residual cardiovascular (CV) risk.
Brent Muhlestein, J, Budoff, Matthew, Le, Viet T, May, Heidi T, Nelson, John R, Roy, Sion   +5 more
core   +2 more sources

Metabolism of n-3 polyunsaturated fatty acids and modification of phospholipids in cultured rabbit aortic smooth muscle cells.

Journal of Lipid Research, 1985
The metabolism of the linolenic acid family (n-3) of fatty acids, e.g., linolenic, eicosapentaenoic, and docosahexaenoic acids, in cultured smooth muscle cells from rabbit aorta was compared to the metabolism of linoleic and arachidonic acids.
N Morisaki, T Kanzaki, Y Fujiyama, I Osawa, K Shirai, N Matsuoka, Y Saito, S Yoshida   +7 more
doaj   +1 more source

Role of EPA in Inflammation: Mechanisms, Effects, and Clinical Relevance

Biomolecules, 2022
Many chronic inflammatory processes are linked with the continuous release of inflammatory mediators and the activation of harmful signal-transduction pathways that are able to facilitate disease progression.
Rosalia Crupi, Salvatore Cuzzocrea
doaj   +1 more source

Fit with good fat? The role of n-3 polyunsaturated fatty acids on exercise performance [PDF]

, 2016
N-3 PUFA (n-3) polyunsaturated fatty acids (PUFA) are a family of fatty acids mainly found in oily fish and fish oil supplements. The effects of n-3 PUFA on health are mainly derived from its anti-inflammatory proprieties and its influence on immune ...
Da Boit, Mariasole, Gray, Stuart M., Hunter, Angus M.   +2 more
core   +3 more sources

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

A transgenic Camelina sativa seed oil effectively replaces fish oil as a dietary source of eicosapentaenoic acid in mice [PDF]

, 2016
Background: Fish currently supplies only 40% of the eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) required to allow all individuals globally to meet the minimum intake recommendation of 500 mg/d.
Betancor, Monica B, Cochard, Marianne, Menoyo, David, Minihane, Anne Marie, Napier, Jonathan A., Rigby, Neil, Ruiz-Lopez, Noemi, Sayanova, Olga, Tejera, Noemi, Tocher, Douglas R., Usher, Sarah, Vauzour, David   +11 more
core   +2 more sources