Results 1 to 10 of about 23,252 (262)

Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Some new 3H-quinazolin-4-one derivatives were synthesised and screened for anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities.
Nahed N. E. El-Sayed, Norah M. Almaneai, Abir Ben Bacha, Omar Al-Obeed, Rehan Ahmad, Maha Abdulla, Ahmed M. Alafeefy   +6 more
doaj   +1 more source

Intraspecific Variation of Centruroides Edwardsii Venom from Two Regions of Colombia

Toxins, 2014
We report the first description studies, partial characterization, and intraspecific difference of Centruroides edwardsii, Gervais 1843, venom. C. edwardsii from two Colombian regions (Antioquia and Tolima) were evaluated.
Sebastián Estrada-Gómez, Nelson Ivan Cupitra, Walter Murillo Arango, Leidy Johana Vargas Muñoz   +3 more
doaj   +1 more source

Subcellular localization of the phospholipases A of rat heart: evidence for a cytosolic phospholipase A1.

Journal of Lipid Research, 1985
During myocardial ischemia increased levels of lysoglycerophospholipids have been reported which may be deleterious to myocardial function. Phospholipases are presumed to be important in the regulation of this process.
G Nalbone, K Y Hostetler
doaj   +1 more source

Approaches to the study of mammalian cellular phospholipases.

Journal of Lipid Research, 1985
The purpose of this article is to present some problems encountered in the study of cellular phospholipases and some approaches used in answering these problems.
M Waite
doaj   +1 more source

Role of Phospholipases in Fungal Fitness, Pathogenicity and Drug Development- Lessons from Cryptococcus neoformans

Frontiers in Microbiology, 2010
Many pathogenic microbes, including many fungi, produce phospholipases which facilitate survival of the pathogen in vivo, invasion and dissemination throughout the host, expression of virulence traits and evasion of host immune defense mechanisms.
Julianne eDjordjevic
doaj   +1 more source

The emerging roles of PAF acetylhydrolase

Journal of Lipid Research, 2009
Platelet-activating factor (PAF), a phospholipid autacoid with potent effects throughout the innate immune system, is selectively degraded by two small families of PAF acetylhydrolases (PAF-AHs).
Thomas M. McIntyre, Stephen M. Prescott, Diana M. Stafforini   +2 more
doaj   +1 more source

Inhibition of nicotinic acetylcholine receptors, a novel facet in the pleiotropic activities of snake venom phospholipases A2.

PLoS ONE, 2014
Phospholipases A2 represent the most abundant family of snake venom proteins. They manifest an array of biological activities, which is constantly expanding. We have recently shown that a protein bitanarin, isolated from the venom of the puff adder Bitis
Catherine A Vulfius, Igor E Kasheverov, Vladislav G Starkov, Alexey V Osipov, Tatyana V Andreeva, Sergey Yu Filkin, Elena V Gorbacheva, Maxim E Astashev, Victor I Tsetlin, Yuri N Utkin   +9 more
doaj   +1 more source

Secretory Phospholipases A2 in Plants

Frontiers in Plant Science, 2019
Secreted phospholipases (sPLA2s) in plants are a growing group of enzymes that catalyze the hydrolysis of sn-2 glycerophospholipids to lysophospholipids and free fatty acids. Until today, around only 20 sPLA2s were reported from plants.
María Elisa Mariani, María Elisa Mariani, María Elisa Mariani, Gerardo Daniel Fidelio, Gerardo Daniel Fidelio   +4 more
doaj   +1 more source

Enzymatic Degumming of Soybean Oil for Raw Material Preparation in BioFuel Production

Applied Sciences
The paper investigates the process of degumming substandard soybean oil using an enzyme complex of phospholipases to prepare it as a feedstock for biodiesel production.
Sviatoslav Polovkovych, Andriy Karkhut, Volodymyr Gunka, Yaroslav Blikharskyy, Roman Nebesnyi, Semen Khomyak, Jacek Selejdak, Zinoviy Blikharskyy   +7 more
doaj   +1 more source

Exploration of the pearl millet phospholipase gene family to identify potential candidates for grain quality traits

BMC Genomics
Background Phospholipases constitute a diverse category of enzymes responsible for the breakdown of phospholipids. Their involvement in signal transduction with a pivotal role in plant development and stress responses is well documented.
Mazahar Moin, Pradeep Reddy Bommineni, Wricha Tyagi   +2 more
doaj   +1 more source