Results 41 to 50 of about 28,776 (298)

Assessment of different Enzymatic Virulence Traits contributing to pathogenicity of Candida Albicans

open access: yesInternational Journal of Endorsing Health Science Research, 2020
Background: Candidiasis is regarded as one of the frequently occurring fungal infections of humans elicited by yeast that belongs to the genus Candida. Among the different species of Candida, Candida albicans is the most pathogenic specie.
Sadia Nazeer   +6 more
doaj   +1 more source

Plant Phospholipases: An Overview

open access: yes, 2012
Plant phospholipases can be grouped into four major types, phospholipase D, phospholipase C, phospholipase A1 (PLA 1), and phospholipase A2 (PLA 2), that hydrolyze glycerophospholipids at different ester bonds.
Stephen Ryu   +5 more
core   +1 more source

In silico analysis of cross reactivity among phospholipases from Hymenoptera species

open access: yes, 2021
: Background: Phospholipases are enzymes with the capacity to hydrolyze membrane lipids and have been characterized in several allergenic sources, such as hymenoptera species. However, cross-reactivity among phospholipases allergens are little understood.
Acevedo Vásquez, Ana Milena   +8 more
core   +1 more source

Lipase maturation factor 1 is required for endothelial lipase activity[S]

open access: yesJournal of Lipid Research, 2011
Lipase maturation factor 1 (Lmf1) is an endoplasmic reticulum (ER) membrane protein involved in the posttranslational folding and/or assembly of lipoprotein lipase (LPL) and hepatic lipase (HL) into active enzymes.
Osnat Ben-Zeev   +9 more
doaj   +1 more source

Interface of Phospholipase Activity, Immune Cell Function, and Atherosclerosis

open access: yesBiomolecules, 2020
Phospholipases are a family of lipid-altering enzymes that can either reduce or increase bioactive lipid levels. Bioactive lipids elicit signaling responses, activate transcription factors, promote G-coupled-protein activity, and modulate membrane ...
Robert M. Schilke   +3 more
doaj   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren   +4 more
wiley   +1 more source

Esterases: Mechanisms of Action, Biological Functions, and Application Prospects

open access: yesApplied Microbiology
Esterases are ubiquitous enzymes found in all living organisms, including animals, plants, and microorganisms. They are involved in several biological processes, including the synthesis and breakdown of biomolecules, such as nucleic acids, lipids, and ...
Arman Mussakhmetov, Dmitriy Silayev
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

Identification of plasma proteins binding oxidized phospholipids using pull-down proteomics and OxLDL masking assay‡

open access: yesJournal of Lipid Research
Oxidized phospholipids (OxPLs) are increasingly recognized as toxic and proinflammatory mediators, which raises interest in the mechanisms of their detoxification.
Philipp Jokesch   +7 more
doaj   +1 more source

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