Results 41 to 50 of about 43,311 (255)

Lipase maturation factor 1 is required for endothelial lipase activity[S]

open access: yesJournal of Lipid Research, 2011
Lipase maturation factor 1 (Lmf1) is an endoplasmic reticulum (ER) membrane protein involved in the posttranslational folding and/or assembly of lipoprotein lipase (LPL) and hepatic lipase (HL) into active enzymes.
Osnat Ben-Zeev   +9 more
doaj   +1 more source

Interface of Phospholipase Activity, Immune Cell Function, and Atherosclerosis

open access: yesBiomolecules, 2020
Phospholipases are a family of lipid-altering enzymes that can either reduce or increase bioactive lipid levels. Bioactive lipids elicit signaling responses, activate transcription factors, promote G-coupled-protein activity, and modulate membrane ...
Robert M. Schilke   +3 more
doaj   +1 more source

Characterization of Plp, a phosphatidylcholine-specific phospholipase and hemolysin of Vibrio anguillarum [PDF]

open access: yes, 2014
Background: Vibrio anguillarum is the causative agent of vibriosis in fish. Several extracellular proteins secreted by V. anguillarum have been shown to contribute to virulence.
Li, Ling, Mou, Xiangyu, Nelson, David R
core   +6 more sources

Esterases: Mechanisms of Action, Biological Functions, and Application Prospects

open access: yesApplied Microbiology
Esterases are ubiquitous enzymes found in all living organisms, including animals, plants, and microorganisms. They are involved in several biological processes, including the synthesis and breakdown of biomolecules, such as nucleic acids, lipids, and ...
Arman Mussakhmetov, Dmitriy Silayev
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phospholipases: From Structure to Biological Function

open access: yesBiomolecules, 2021
Phospholipases are enzymes that cleave ester bonds within phospholipids [...]
María A. Balboa, Jesús Balsinde
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Identification of plasma proteins binding oxidized phospholipids using pull-down proteomics and OxLDL masking assay‡

open access: yesJournal of Lipid Research
Oxidized phospholipids (OxPLs) are increasingly recognized as toxic and proinflammatory mediators, which raises interest in the mechanisms of their detoxification.
Philipp Jokesch   +7 more
doaj   +1 more source

GPI-AP release in cellular, developmental, and reproductive biology

open access: yesJournal of Lipid Research, 2016
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) contain a covalently linked GPI anchor located on outer cell membranes. GPI-APs are ubiquitously conserved from protozoa to vertebrates and are critical for physiological events such as development,
Yoshitaka Fujihara, Masahito Ikawa
doaj   +1 more source

Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]

open access: yes, 2011
Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Balmer, L.   +5 more
core   +2 more sources

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