Results 21 to 30 of about 43,311 (255)

2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A2. [PDF]

, 2017
Cytosolic phospholipase A2 (GIVA cPLA2) is the only PLA2 that exhibits a marked preference for hydrolysis of arachidonic acid containing phospholipid substrates releasing free arachidonic acid and lysophospholipids and giving rise to the generation of ...
Barbayianni, Efrosini, Dennis, Edward A, Galiatsatou, Gerasimia, Kokotos, George, Kokotou, Maroula G, Koutoulogenis, Giorgos, Limnios, Dimitris, Magrioti, Victoria, Mouchlis, Varnavas D, Navratil, Aaron, Satpathy, Banita   +10 more
core   +1 more source

Nuclear Inositides and Inositide-Dependent Signaling Pathways in Myelodysplastic Syndromes

Cells, 2020
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematological malignancies characterized by peripheral blood cytopenia and abnormal myeloproliferation, as well as a variable risk of evolution into acute myeloid leukemia (AML). The nucleus is
Jie Xian, Eric Owusu Obeng, Stefano Ratti, Isabella Rusciano, Maria Vittoria Marvi, Antonietta Fazio, Alessia De Stefano, Sara Mongiorgi, Alessandra Cappellini, Giulia Ramazzotti, Lucia Manzoli, Lucio Cocco, Matilde Yung Follo   +12 more
doaj   +1 more source

Analysis of High Molecular Mass Compounds from the Spider Pamphobeteus verdolaga Venom Gland. A Transcriptomic and MS ID Approach

Toxins, 2021
Nowadays, spider venom research focuses on the neurotoxic activity of small peptides. In this study, we investigated high-molecular-mass compounds that have either enzymatic activity or housekeeping functions present in either the venom gland or venom of
Sebastian Estrada-Gómez, Leidy Johana Vargas-Muñoz, Cesar Segura Latorre, Monica Maria Saldarriaga-Cordoba, Claudia Marcela Arenas-Gómez   +4 more
doaj   +1 more source

Candida albicans pathogenicity mechanisms [PDF]

, 2013
Peer reviewedPublisher ...
Alonso-Monge R, Braun BR, Csank C, De Bernardis F, Diez-Orejas R, Fonzi WA, Hube B, Hwang CS, Mühlschlegel FA, Sorger PK, Wysong DR   +10 more
core   +1 more source

Candida albicans and non-albicans Isolates from Bloodstream Have Different Capacities to Induce Neutrophil Extracellular Traps

Journal of Fungi, 2019
Neutrophils activated with pathogens or their products induce formation of extracellular traps (NETs), but if this constitutes a general response against all pathogenic species in a single genus or intrageneric differences exist remains unknown, yet this
Lizbeth Campos-Garcia, Rocio Jimena Jimenez-Valdes, Romel Hernandez-Bello, Jose Palma-Nicolas, Gloria Maria Gonzalez, Alejandro Sanchez-Gonzalez   +5 more
doaj   +1 more source

An Integrated Proteomic and Transcriptomic Analysis Reveals the Venom Complexity of the Bullet Ant Paraponera clavata

Toxins, 2020
A critical hurdle in ant venom proteomic investigations is the lack of databases to comprehensively and specifically identify the sequence and function of venom proteins and peptides.
Samira R. Aili, Axel Touchard, Regan Hayward, Samuel D. Robinson, Sandy S. Pineda, Hadrien Lalagüe, Mrinalini, Irina Vetter, Eivind A. B. Undheim, R. Manjunatha Kini, Pierre Escoubas, Matthew P. Padula, Garry S. A. Myers, Graham M. Nicholson   +13 more
doaj   +1 more source

An amphitropic cAMP-binding protein in yeast mitochondria [PDF]

, 1989
: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W., Baranska J., Blok M., Brugge J., Burn P., Burn P., Cascales S. C., Cobon G. S., Cobon G. S., Cornell R., Courtneidge S. A., Cross G. A. M., Dils R. R., Dygas A., Gillfillan A. M., Guarnieri M., Hixson C. S., Hostetler K. Y., Jelsema C. L., Kraft A. S., Lassing I., Lassing I., Low M. G., Megli F. M., Meyer R. K., Muller G., Muller G., Muller G., Muller G., Nishizuka Y., Pelech S. L., Radika R., Rodel G., Rotman A., Schmidt M. F. G., Sefton B. M., Sleight R., Terce F., Towbin H., Wirtz K. W. A., Wirtz K. W. A., Wojtczak L., Yaffe M., Zborowski J.   +43 more
core   +3 more sources

Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]

, 2015
Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J., Gay, Claudia Carolina, Pla, Davinia, Sanz, Libia   +3 more
core   +5 more sources

The grease trap: uncovering the mechanism of the hydrophobic lid in Cutibacterium acnes lipase[S]

Journal of Lipid Research, 2020
Acne is one of the most common dermatological conditions, but the details of its pathology are unclear, and current management regimens often have adverse effects. Cutibacterium acnes is known as a major acne-associated bacterium that derives energy from
Hyo Jung Kim, Bong-Jin Lee, Ae-Ran Kwon
doaj   +1 more source

Emulsifier and antioxidant properties of by-products obtained by enzymatic degumming of soybean oil [PDF]

, 2013
The enzymes used in degumming, called phospholipases, specifically act on phospholipids without degrading the oil itself. Degumming using a phospholipase C enzyme allows to meet all market specifications while it increases the oil yield.
AOCS, Autino, Cabezas, Cabezas, Cabezas, Cardenia, Clausen, Diehl, Dijkstra, Galhardo, Gordon, Gutiérrez, Ixtaina, Johnson, Judde, Manjula, Mc Clements, Márquez, Pan, Pokorný, Saito, Shukla, Sosada, van Nieuwenhuyzen, van Nieuwenhuyzen, van Nieuwenhuyzen, Verleyen, Wu, Wu   +28 more
core   +2 more sources