Results 21 to 30 of about 23,252 (262)

PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids

Journal of Lipid Research, 2020
The plasma membrane of neurons consists of distinct domains, each of which carries specialized functions and a characteristic set of membrane proteins.
Hideaki Kuge, Izumi Miyamoto, Ken-ichi Yagyu, Koichi Honke   +3 more
doaj   +1 more source

Anti-Candida Activity of Geraniol: Effect on Hydrolytic Enzyme Secretion and Biofilm Formation

Journal of Pure and Applied Microbiology, 2018
Existing antifungal drugs available today are low in efficacy, high in toxicity and cause multidrug resistance. Anti-Candida potential of geraniol, an acyclic monoterpene alcohol was evaluated and secretion of hydrolytic enzymes, adherence and biofilm ...
Yamini Sharma, Sumit Kumar Rastogi, Sahar Saadallah Amin Saadallah, Khadija Al Fadel, Nikhat Manzoor   +4 more
doaj   +1 more source

Phospholipase gene expression during Paracoccidioides brasiliensis morphological transition and infection

Memorias do Instituto Oswaldo Cruz, 2013
Phospholipase is an important virulence factor for pathogenic fungi. In this study, we demonstrate the following: (i) the Paracoccidioides brasiliensis pld gene is preferentially expressed in mycelium cells, (ii) the plb1 gene is mostly up-regulated by ...
Deyze Alencar Soares, Marilia Barros Oliveira, Adriane Feijo Evangelista, Emerson Jose Venancio, Rosangela Vieira Andrade, Maria Sueli Soares Felipe, Silvana Petrofeza   +6 more
doaj   +1 more source

In silico analysis of cross reactivity among phospholipases from Hymenoptera species [version 2; peer review: 2 approved]

F1000Research, 2021
Background: Phospholipases are enzymes with the capacity to hydrolyze membrane lipids and have been characterized in several allergenic sources, such as hymenoptera species.
Yuliana Emiliani, Andrés Sánchez, Marlon Munera, Jorge Sánchez, Dilia Aparicio   +4 more
doaj   +1 more source

A rare case of the complex phenotype of hereditary spastic paraparesis due to a mutation in a novel gene variant

Journal of Current Research in Scientific Medicine, 2022
Hereditary spastic paraplegia (HSP), is a heterogeneous group of corticospinal tract disorders leading to progressive lower limb weakness and spasticity.
B Jude Antonieo Raja, Sakthi Abirami, Priya Jose, Peter Prasanth Kumar Kommu   +3 more
doaj   +1 more source

Signal-activated phospholipase regulation of leukocyte chemotaxis

Journal of Lipid Research, 2009
Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
doaj   +1 more source

Tag-SNPs in Phospholipase-Related Genes Modify the Susceptibility to Nephrosclerosis and its Associated Cardiovascular Risk

Frontiers in Pharmacology, 2022
Nephrosclerosis patients have a high cardiovascular (CV) risk that is very often of more concern than the renal disease itself. We aimed to determine whether variants in phospholipase-related genes, associated with atherosclerosis and CV outcomes in the ...
Luz M. González, Nicolás R. Robles, Nicolás R. Robles, Sonia Mota-Zamorano, Sonia Mota-Zamorano, José C. Arévalo-Lorido, José Manuel Valdivielso, José Manuel Valdivielso, Juan López-Gómez, Guillermo Gervasini, Guillermo Gervasini   +10 more
doaj   +1 more source

Nuclear Inositides and Inositide-Dependent Signaling Pathways in Myelodysplastic Syndromes

Cells, 2020
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematological malignancies characterized by peripheral blood cytopenia and abnormal myeloproliferation, as well as a variable risk of evolution into acute myeloid leukemia (AML). The nucleus is
Jie Xian, Eric Owusu Obeng, Stefano Ratti, Isabella Rusciano, Maria Vittoria Marvi, Antonietta Fazio, Alessia De Stefano, Sara Mongiorgi, Alessandra Cappellini, Giulia Ramazzotti, Lucia Manzoli, Lucio Cocco, Matilde Yung Follo   +12 more
doaj   +1 more source

Analysis of High Molecular Mass Compounds from the Spider Pamphobeteus verdolaga Venom Gland. A Transcriptomic and MS ID Approach

Toxins, 2021
Nowadays, spider venom research focuses on the neurotoxic activity of small peptides. In this study, we investigated high-molecular-mass compounds that have either enzymatic activity or housekeeping functions present in either the venom gland or venom of
Sebastian Estrada-Gómez, Leidy Johana Vargas-Muñoz, Cesar Segura Latorre, Monica Maria Saldarriaga-Cordoba, Claudia Marcela Arenas-Gómez   +4 more
doaj   +1 more source

PTEN regulates phospholipase D and phospholipase C [PDF]

Human Molecular Genetics, 2007
PTEN is an ubiquitously expressed tumor suppressor which plays a prominent role in the pathogenesis of many types of sporadic solid tumors, including breast cancer, as well as hematologic malignancies. Germline PTEN mutations cause 85% of Cowden syndrome (CS), characterized by a high risk of breast and thyroid cancers, and 65% of Bannayan-Riley ...
Christopher A, Alvarez-Breckenridge, Kristin A, Waite, Charis, Eng   +2 more
openaire   +2 more sources