Results 21 to 30 of about 28,776 (298)
Nuclear Inositides and Inositide-Dependent Signaling Pathways in Myelodysplastic Syndromes
Cells, 2020 Myelodysplastic syndromes (MDS) are a heterogeneous group of hematological malignancies characterized by peripheral blood cytopenia and abnormal myeloproliferation, as well as a variable risk of evolution into acute myeloid leukemia (AML). The nucleus is
Jie Xian +12 more
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Toxins, 2021 Nowadays, spider venom research focuses on the neurotoxic activity of small peptides. In this study, we investigated high-molecular-mass compounds that have either enzymatic activity or housekeeping functions present in either the venom gland or venom of
Sebastian Estrada-Gómez +4 more
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, 2019 Phospholipase C (PLC) family members constitute a family of diverse enzymes. Thirteen different family members have been cloned. These family members have unique structures that mediate various functions. Although PLC family members all appear to signal through the bi-products of cleaving phospholipids, it is clear that each family member, and at times
Colin A, Bill, Charlotte M, Vines
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Journal of Fungi, 2019 Neutrophils activated with pathogens or their products induce formation of extracellular traps (NETs), but if this constitutes a general response against all pathogenic species in a single genus or intrageneric differences exist remains unknown, yet this
Lizbeth Campos-Garcia +5 more
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Differentiation-dependent regulation of secreted phospholipases A2 in murine epidermis [PDF]
, 2003 The action of secreted phospholipases A2 in skin is thought to be essential for epidermal barrier homeostasis. The incomplete knowledge of presence and functions of the novel secreted phospholipase A2 subtypes in skin prompted us to explore their ...
Gurrieri, Silvia +19 more
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Toxins, 2020 A critical hurdle in ant venom proteomic investigations is the lack of databases to comprehensively and specifically identify the sequence and function of venom proteins and peptides.
Samira R. Aili +13 more
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PTEN regulates phospholipase D and phospholipase C [PDF]
Human Molecular Genetics, 2007 PTEN is an ubiquitously expressed tumor suppressor which plays a prominent role in the pathogenesis of many types of sporadic solid tumors, including breast cancer, as well as hematologic malignancies. Germline PTEN mutations cause 85% of Cowden syndrome (CS), characterized by a high risk of breast and thyroid cancers, and 65% of Bannayan-Riley ...
Christopher A, Alvarez-Breckenridge +2 more
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Bacterial Type 6 Secreted Phospholipases Play Family Feud [PDF]
, 2013 Secreted bacterial phospholipases play many important roles in host-pathogen interactions. In a recent study, Russell et al. (2013) revealed a new role for highly conserved proteobacterial phospholipases in bacterium-bacterium ...
Hammond, John H., Hogan, Deborah A.
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The grease trap: uncovering the mechanism of the hydrophobic lid in Cutibacterium acnes lipase[S]
Journal of Lipid Research, 2020 Acne is one of the most common dermatological conditions, but the details of its pathology are unclear, and current management regimens often have adverse effects. Cutibacterium acnes is known as a major acne-associated bacterium that derives energy from
Hyo Jung Kim, Bong-Jin Lee, Ae-Ran Kwon
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Role of Phospholipases A2 as Anti-Covid 19
, 2020 In this review trial has been made for the search of anti-covid 19, so my idea depends on the choice of phospholipases A2 as anti-covid 19 depending on the following evidences: Phospholipases (PLs) are a ubiquitous group of enzymes that share the ...
Abdel Fattah, Mohy El Din
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