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Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in ...
Richmond, Gregory S., Smith, Terry K.
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Phospholipases A in Trypanosomatids [PDF]
Phospholipases are a complex and important group of enzymes widespread in nature, that play crucial roles in diverse biochemical processes and are classified as A1, A2, C, and D. Phospholipases A1and A2activities have been linked to pathogenesis in various microorganisms, and particularly in pathogenic protozoa they have been implicated in cell ...
María Laura Belaunzarán +2 more
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The Phospholipases A of Epidermis [PDF]
Phospholipases A have been characterized in fetal rat epidermis. Both a calcium dependent phospholipase A with pH optimum of 8.5 and a calcium independent enzyme with a pH optimum of 4.5 were found. Activity against both acyl groups of phosphatidyl choline were found for both enzymes and the findings suggested that the acid enzyme (pH 4.5) is primarily
Freinkel, Ruth K., Traczyk, Thomas N.
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Phospholipases: From Structure to Biological Function
Phospholipases are enzymes that cleave ester bonds within phospholipids [...]
María A. Balboa, Jesús Balsinde
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Recent Advances in the Cellular and Developmental Biology of Phospholipases in Plants [PDF]
Phospholipases (PLs) are lipid-hydrolyzing enzymes known to have diverse signaling roles during plant abiotic and biotic stress responses. They catalyze lipid remodeling, which is required to generate rapid responses of plants to environmental cues ...
Tomáš Takáč +2 more
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Phospholipases: From Structure to Biological Function [PDF]
Phospholipases are a ubiquitous group of enzymes that hydrolyze ester bonds within membrane phospholipids. These enzymes serve multiple biological functions that go far beyond a mere membrane remodeling role in cellular homeostasis; they also play key ...
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In this chapter, we initially elaborate on the identification and characterization of brown spider venom phospholipases D (BSVPLDs) based on “omics” approaches, with an emphasis on transcriptomic and proteomic analyses.
Polli, Nayanne Louise Costacurta +10 more
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Background: Phospholipases are enzymes with the capacity to hydrolyze membrane lipids and have been characterized in several allergenic sources, such as hymenoptera species.
Yuliana Emiliani +4 more
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Hereditary spastic paraplegia (HSP), is a heterogeneous group of corticospinal tract disorders leading to progressive lower limb weakness and spasticity.
B Jude Antonieo Raja +3 more
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Nephrosclerosis patients have a high cardiovascular (CV) risk that is very often of more concern than the renal disease itself. We aimed to determine whether variants in phospholipase-related genes, associated with atherosclerosis and CV outcomes in the ...
Luz M. González +10 more
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