Results 11 to 20 of about 43,311 (255)

Secretory Phospholipases A2 in Plants [PDF]

Frontiers in Plant Science, 2019
Secreted phospholipases (sPLA2s) in plants are a growing group of enzymes that catalyze the hydrolysis of sn-2 glycerophospholipids to lysophospholipids and free fatty acids. Until today, around only 20 sPLA2s were reported from plants.
María Elisa Mariani, María Elisa Mariani, María Elisa Mariani, Gerardo Daniel Fidelio, Gerardo Daniel Fidelio   +4 more
doaj   +3 more sources

Role of Phospholipases in Fungal Fitness, Pathogenicity and Drug Development- Lessons from Cryptococcus neoformans [PDF]

Frontiers in Microbiology, 2010
Many pathogenic microbes, including many fungi, produce phospholipases which facilitate survival of the pathogen in vivo, invasion and dissemination throughout the host, expression of virulence traits and evasion of host immune defense mechanisms.
Julianne eDjordjevic
doaj   +2 more sources

Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]

, 2019
Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron, Dennis, Edward A, Mouchlis, Varnavas D   +2 more
core   +6 more sources

Identification of caspase 3 motifs and critical aspartate residues in human Phospholipase D1b and Phopsholipase D2a [PDF]

, 2008
Stimulation of mammalian cells frequently initiates phospholipase D-catalysed hydrolysis of phosphatidylcholine in the plasma membrane to yield phosphatidic acid (PA) a novel lipid messenger.
Ahn, Avila-Flores, Brown, Cazzolli, Chen, Cross, Degterev, Du, Earnshaw, Farquhar, Fisher, Graham Ladds, Guimaraes, Hodgkin, Hui, Iwasaki-Bessho, Kasai, Kusner, Lim, Matthew N. Hodgkin, McDermott, Michelle H. Wright, Michelle J. Farquhar, Mina-olga Aletrari, Nakashima, Nozawa, Oh, O’Luanaigh, Palicz, Park, Ponting, Powner, Powner, Rozengurt, Samejima, Shi, Timmer, Wissing, Xie, Yamada, Zeniou-Meyer, Zhao, Zheng, Zhong   +43 more
core   +1 more source

Phospholipase gene expression during Paracoccidioides brasiliensis morphological transition and infection

Memorias do Instituto Oswaldo Cruz, 2013
Phospholipase is an important virulence factor for pathogenic fungi. In this study, we demonstrate the following: (i) the Paracoccidioides brasiliensis pld gene is preferentially expressed in mycelium cells, (ii) the plb1 gene is mostly up-regulated by ...
Deyze Alencar Soares, Marilia Barros Oliveira, Adriane Feijo Evangelista, Emerson Jose Venancio, Rosangela Vieira Andrade, Maria Sueli Soares Felipe, Silvana Petrofeza   +6 more
doaj   +1 more source

In silico analysis of cross reactivity among phospholipases from Hymenoptera species [version 2; peer review: 2 approved]

F1000Research, 2021
Background: Phospholipases are enzymes with the capacity to hydrolyze membrane lipids and have been characterized in several allergenic sources, such as hymenoptera species.
Yuliana Emiliani, Andrés Sánchez, Marlon Munera, Jorge Sánchez, Dilia Aparicio   +4 more
doaj   +1 more source

A rare case of the complex phenotype of hereditary spastic paraparesis due to a mutation in a novel gene variant

Journal of Current Research in Scientific Medicine, 2022
Hereditary spastic paraplegia (HSP), is a heterogeneous group of corticospinal tract disorders leading to progressive lower limb weakness and spasticity.
B Jude Antonieo Raja, Sakthi Abirami, Priya Jose, Peter Prasanth Kumar Kommu   +3 more
doaj   +1 more source

Cyclosporin A inhibits PGE2 release from vascular smooth muscle cells [PDF]

, 1987
The influence of the fungoid undecapeptide cyclosporin A (CyA) on PGE2 release from cultured rat aortic smooth muscle cells was investigated in this study.
Koch, K. M., Kurtz, Armin, Kühn, K., Pfeilschifter, J.   +3 more
core   +1 more source

Signal-activated phospholipase regulation of leukocyte chemotaxis

Journal of Lipid Research, 2009
Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
doaj   +1 more source

Tag-SNPs in Phospholipase-Related Genes Modify the Susceptibility to Nephrosclerosis and its Associated Cardiovascular Risk

Frontiers in Pharmacology, 2022
Nephrosclerosis patients have a high cardiovascular (CV) risk that is very often of more concern than the renal disease itself. We aimed to determine whether variants in phospholipase-related genes, associated with atherosclerosis and CV outcomes in the ...
Luz M. González, Nicolás R. Robles, Nicolás R. Robles, Sonia Mota-Zamorano, Sonia Mota-Zamorano, José C. Arévalo-Lorido, José Manuel Valdivielso, José Manuel Valdivielso, Juan López-Gómez, Guillermo Gervasini, Guillermo Gervasini   +10 more
doaj   +1 more source