Phospholipase D regulates ferroptosis signal transduction in mouse spleen hypoxia response [PDF]
High-altitude hypoxia exposure can lead to phospholipase D-mediated lipid metabolism disorder in spleen tissues and induce ferroptosis. Nonetheless, the key genes underlying hypoxia-induced splenic phospholipase D and the ferroptosis pathway remain ...
Jiayang Wang +7 more
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Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates [PDF]
Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira +9 more
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Switching the substrate specificity of lysoplasmalogen‐specific phospholipase D [PDF]
Lysoplasmalogen‐specific phospholipase D (LyPls‐PLD) catalyzes reactions in a manner similar to those catalyzed by glycerophosphodiester phosphodiesterase (GDPD) and other well‐known PLDs.
Takayuki Oyama +2 more
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Phospholipase D: emerging therapeutic targets in signaling, metabolism, and immune-oncology [PDF]
The phospholipase D (PLD) family, comprising six evolutionarily conserved isoforms (PLD1-6), serves as master regulators of lipid signaling, membrane dynamics, and cellular communication.
Lin Tang +6 more
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Characteristics of Phospholipase D and Application in the Synthesis of Phosphatidylserine
Phosphatidylserine (PS) is a new resource food, which has less content in nature and the difficulty of extraction. Phospholipase D (PLD) is the critical synthetase in enzymatic preparation of PS.
Bishan GUO +7 more
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Phosphatidylserine (PS) was shown to work synergistically with tocopherols to extend the shelf life of oil-in-water emulsions. However, the high cost of PS prevents it from being used as a food additive. This work investigated the potential use of a high-
Harshika Arora +2 more
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Phosphatides content in soybean oil in function of bean moisture content-at-harvest and storage-time
The influence of soybean moisture content-at-harvest and storage time upon total and non-hydratable phosphatides content in oil and bean phospholipase D activity was evaluated.
Enzo A. Tosi +3 more
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Phosphatidic acid production regulated by receptors with liganddependent tyrosine kinase activity
The present study deals with the most recent and important studies on the relationship between transmembrane receptors with ligand-dependent tyrosine kinase activity and cellular lipid metabolism, predominantly in generating phosphatidic acid (PA) as a ...
Fco. J. G. Muriana, V. Ruiz-Gutiérrez
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Early LPS-induced ERK activation in retinal pigment epithelium cells is dependent on PIP2-PLC
This article presents additional data regarding the study “The phospholipase D pathway mediates the inflammatory response of the retinal pigment epithelium” [1]. The new data presented here show that short exposure of RPE cells to lipopolysaccharide (LPS)
Melina V. Mateos +3 more
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Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis
Critical developmental periods, such as fertilization, involve metabolic activation, membrane fusion events such as sperm-egg or plasma membrane-cortical granule merger, and production and hydrolysis of phospholipids.
Douglas W. Petcoff +2 more
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