Results 21 to 30 of about 117,202 (259)
Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain
Molecules, 2022 Phospholipase is an enzyme that hydrolyzes various phospholipid substrates at specific ester bonds and plays important roles such as membrane remodeling, as digestive enzymes, and the regulation of cellular mechanism.
Yunseok Heo +8 more
doaj +1 more source
Phosphatidic acid: a lipid regulator of the Hippo pathway
Molecular & Cellular Oncology, 2019 The Hippo pathway, a signaling pathway highly conserved across species, plays a crucial role in organ size control and cancer suppression. Our recent study shows that phosphatidic acid can regulate the Hippo pathway through a physical lipid-protein ...
Han Han +3 more
doaj +1 more source
Molecular diversity of phospholipase D in angiosperms
BMC Genomics, 2002 Background The phospholipase D (PLD) family has been identified in plants by recent molecular studies, fostered by the emerging importance of plant PLDs in stress physiology and signal transduction.
Cvrčková Fatima +3 more
doaj +1 more source
European Journal of Histochemistry, 2009 DAG, 1,2-diacylglycerol; EGF, epidermal growth factor; TNF, tumour necrosis factor; IGF-I, insulinlike growth factor I; Ins(n)P, inositol phosphate; Ins(n,n)P2, inositol bisphosphate; Ins(n,n,n)P3, inositol trisphosphate; MEL, murine erythroleukemia ...
C D'Santos +4 more
doaj +3 more sources
Identification and Expression Analysis of the Phospholipase D Gene Family in Rice
Guangdong nongye kexue【Objective】Phospholipase D (PLD) plays a crucial role in plant growth, development, and stress response. The study was conducted to explore the PLD gene family members involved in biotic and abiotic stress in rice (Oryza sativa L.) and investigate their ...
Huasheng CAO +8 more
doaj +1 more source
Effect of GM2 activator protein on the enzymatic hydrolysis of phospholipids and sphingomyelin
Journal of Lipid Research, 2003 GM2 activator protein (GM2AP) is a specific protein cofactor that stimulates the enzymatic hydrolysis of the GalNAc from GM2, a sialic acid containing glycosphingolipid, both in vitro and in lysosomes. While phospholipids together with glycosphingolipids
Yoshimi Shimada, Yu-Teh Li, Su-Chen Li
doaj +1 more source
Relationship between NAFLD and coronary artery disease: A Mendelian randomization study
Hepatology, EarlyView., 2022 Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren +4 more
wiley +1 more source
Recent Advances in the Cellular and Developmental Biology of Phospholipases in Plants
Frontiers in Plant Science, 2019 Phospholipases (PLs) are lipid-hydrolyzing enzymes known to have diverse signaling roles during plant abiotic and biotic stress responses. They catalyze lipid remodeling, which is required to generate rapid responses of plants to environmental cues ...
Tomáš Takáč +2 more
doaj +1 more source
NAFLD‐related hepatocellular carcinoma: The growing challenge
Hepatology, EarlyView., 2022 Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah +2 more
wiley +1 more source
Toxins, 2017 Hemoscorpius lepturus is the most medically important scorpion in Iran. The clinical signs of H. lepturus envenomation are remarkably similar to those reported for brown spiders, including dermonecrosis, hematuria, renal failure and even death.
Elham Torabi +7 more
doaj +1 more source