Results 1 to 10 of about 133,836 (210)

Curcumin modulates dopaminergic receptor, CREB and phospholipase c gene expression in the cerebral cortex and cerebellum of streptozotocin induced diabetic rats

Journal of Biomedical Science, 2010
Curcumin, an active principle component in rhizome of Curcuma longa, has proved its merit for diabetes through its anti-oxidative and anti-inflammatory properties.
George Naijil, Gireesh G, Antony Sherin, Kumar T Peeyush, Paulose CS   +4 more
doaj   +1 more source

Pharmacological Evidence for Involvement of Phospholipase D, Protein Kinase C, and Sodium-Calcium Exchanger in -Adrenoceptor-Mediated Negative Inotropy in Adult Mouse Ventricle

Journal of Pharmacological Sciences, 2003
The intracellular signalling pathway for a-adrenoceptor-mediated negative inotropy was studied pharmacologically in isolated adult mouse ventricle. The negative inotropy was inhibited by GF-109203X, a nonselective protein kinase C inhibitor.
Kazuhide Nishimaru, Yoshio Tanaka, Hikaru Tanaka, Koki Shigenobu   +3 more
doaj   +1 more source

Relation of lipid structure of sarcotubular vesicles to Ca++ transport activity

Journal of Lipid Research, 1968
The role of lipids of the sarcotubular membranes in their Ca++ uptake and Mg-ATPase activities was investigated. Treatment of the membranes with phospholipase C inhibits both processes. Treatment with phospholipase A and phospholipase D, which results in
B.P. Yu, F.D. DeMartinis, E.J. Masoro
doaj   +1 more source

Evaluation of proteinase and phospholipase activity of Candida albicans strains isolated from the mouth of patients with controlled and uncontrolled diabetes mellitus in Qazvin province: Short Communication

مجله دانشگاه علوم پزشکی بیرجند, 2021
Pathophysiological changes in the mouth of patients with diabetes mellitus (DM) predispose to overgrowth of Candida albicans. Various virulence factors such as proteinase and phospholipase production are involved in the process of degradation of the host
Faezeh Mohammadi, Hossein Safasepehr, Sima Hashemipour, Monirsadat Mirzadeh   +3 more
doaj  

Phospholipases in the Response of Fortune Mandarins to Heat and Cold Stress and in the Heat-Induced Cross-Adaption to Chilling

Horticulturae
Phospholipases (PLs) are key enzymes involved in membrane remodeling, structure, and signaling during plant stress responses. This study analyzed early and long-term transcriptional regulation of PL isoforms—PLD (CsPLDα,β,δ,γ,ζ), PLA (CsPLA2α,2β, CsPAT1),
Paco Romero, Raúl Sampedro, Fernando Alférez, María T. Lafuente   +3 more
doaj   +1 more source

Phospholipase C-γ as a Potential Therapeutic Target for Graves' Orbitopathy. [PDF]

Endocrinol Metab (Seoul), 2023
Roh TH, Chae MK, Ko JS, Kikkawa DO, Jang SY, Yoon JS.   +5 more
europepmc   +1 more source

Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function

eLife
Phospholipase C isozymes (PLCs) hydrolyze phosphatidylinositol 4,5-bisphosphate (PIP2) into inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), important signaling molecules involved in many cellular processes including Ca2+ release from the ...
Mengqi Ma, Yiming Zheng, Mingxi Deng, Shenzhao Lu, Xueyang Pan, Xi Luo, Michelle Etoundi, David Li-Kroeger, Kim C Worley, Lindsay C Burrage, Lauren S Blieden, Aimee Allworth, Wei-Liang Chen, Giuseppe Merla, Barbara Mandriani, Catherine E Otten, Pierre Blanc, Jill A Rosenfeld, Debdeep Dutta, Shinya Yamamoto, Michael F Wangler, Ian A Glass, Jingheng Chen, Elizabeth Blue, Paolo Prontera, Jeremie Rosain, Sandrine Marlin, Seema R Lalani, Hugo J Bellen, Undiagnosed Diseases Network   +29 more
doaj   +1 more source

Phospholipase C in Beijing strains of Mycobacterium tuberculosis

Iranian Journal of Microbiology, 2010
Background and Objectives: Phospholipase of Mycobacterium tuberculosis plays an important role in pathogenesis through breaking up phospholipids and production of diacylglycerol.
H Goudarzi, ES Mirsamadi, S Jahani Sherafat, M Esfahani, N Faramarzi, P Farnia   +5 more
doaj  

Activation Mechanisms and Diverse Functions of Mammalian Phospholipase C. [PDF]

Biomolecules, 2023
Kanemaru K, Nakamura Y.
europepmc   +1 more source

Sphingosylphosphorylcholine is a substrate for the <i>Pseudomonas aeruginosa</i> phospholipase C/sphingomyelinase, PlcH. [PDF]

Microbiol Spectr
DiGianivittorio P, Schutz K, Hinkel LA, Wargo MJ.   +3 more
europepmc   +1 more source