Results 21 to 30 of about 133,836 (210)

Phospholipase C is a novel regulator at the early stages of microspore embryogenesis in Nicotiana tabacum

open access: yesPlant Signaling & Behavior, 2022
Microspore transfers the developmental fate into embryogenesis in vitro regulated by determinant factors of stress-induced. However, the key regulators of microspore embryogenesis (ME) are still largely undiscovered to reveal the mechanism of cell fate ...
Pan Luo   +7 more
doaj   +1 more source

Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain

open access: yesMolecules, 2022
Phospholipase is an enzyme that hydrolyzes various phospholipid substrates at specific ester bonds and plays important roles such as membrane remodeling, as digestive enzymes, and the regulation of cellular mechanism.
Yunseok Heo   +8 more
doaj   +1 more source

Phospholipase C isozymes as effectors of Ras superfamily GTPases

open access: yesJournal of Lipid Research, 2009
The physiological effects of many extracellular stimuli are initiated through receptor-promoted activation of phospholipase C and inositol lipid signaling pathways.
T. Kendall Harden   +2 more
doaj   +1 more source

Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis

open access: yesJournal of Lipid Research, 2008
Critical developmental periods, such as fertilization, involve metabolic activation, membrane fusion events such as sperm-egg or plasma membrane-cortical granule merger, and production and hydrolysis of phospholipids.
Douglas W. Petcoff   +2 more
doaj   +1 more source

Current data on the effectiveness of gliclazide and molecular mechanisms of action of the drug

open access: yesСахарный диабет, 2020
With the growing prevalence of type 2 diabetes mellitus (T2DM) the possibility of treating it with available drugs is one of the main issues. Although glycemic control and reduction of micro- and macrovascular outcomes remain important aspects of ...
Nina A. Petunina   +2 more
doaj   +1 more source

Activation of phospholipase D-2 by P2X7 agonists in rat submandibular gland acini

open access: yesJournal of Lipid Research, 2002
Exogenous ATP stimulated phospholipase D (PLD), but not sphingomyelinase in rat submandibular gland (SMG) acini. PLD activation was dependent upon extracellular Ca2+ and did not involve intracellular Ca2+ mobilization or phosphoinositide-specific ...
Encarnación Pérez-Andrés   +11 more
doaj   +1 more source

Variable Surface Glycoprotein from Trypanosoma brucei Undergoes Cleavage by Matrix Metalloproteinases: An in silico Approach

open access: yesPathogens, 2019
In order to survive as extracellular parasites in the mammalian host environment, Trypanosoma brucei has developed efficient mechanisms of immune system evasion, which include the abundant expression of a variable surface glycoprotein (VSG) coat.
Cláudia Jassica Gonçalves Moreno   +2 more
doaj   +1 more source

Lipid vesicle fusion induced by phospholipase C activity in model bile.

open access: yesJournal of Lipid Research, 1993
Using a system of phosphatidylcholine-cholesterol vesicles to model the vesicle phase of mammalian bile (1:1 molar ratio) we evaluated whether very small amounts of C.
TE Little, H Madani, SP Lee, EW Kaler
doaj   +1 more source

Isolation, Characterization, and Biological Activity of Phospholipase A2 (PLA2) and Hyaluronidase from Iranian Honey Bee Venom (Apis Mellifera meda) [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2023
ObjectiveBee venom contains various enzymes such as hyaluronidase and phospholipase A2, which have medical and pharmaceutical applications. In several studies, the activity of phospholipase A2 and hyaluronidase has been reported in different bee species,
Mahmood Nazari   +2 more
doaj   +1 more source

Nuclear inositides

open access: yesEuropean Journal of Histochemistry, 2009
DAG, 1,2-diacylglycerol; EGF, epidermal growth factor; TNF, tumour necrosis factor; IGF-I, insulinlike growth factor I; Ins(n)P, inositol phosphate; Ins(n,n)P2, inositol bisphosphate; Ins(n,n,n)P3, inositol trisphosphate; MEL, murine erythroleukemia ...
C D'Santos   +4 more
doaj   +3 more sources

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