Results 1 to 10 of about 79,638 (253)

Sensing Phosphatidylserine in Cellular Membranes

open access: yesSensors, 2011
Phosphatidylserine, a phospholipid with a negatively charged head-group, is an important constituent of eukaryotic cellular membranes. On the plasma membrane, rather than being evenly distributed, phosphatidylserine is found preferentially in the inner ...
Jason G Kay, Sergio Grinstein
exaly   +4 more sources

Stabilin Receptors: Role as Phosphatidylserine Receptors

open access: yesBiomolecules, 2019
Phosphatidylserine is a membrane phospholipid that is localized to the inner leaflet of the plasma membrane. Phosphatidylserine externalization to the outer leaflet of the plasma membrane is an important signal for various physiological processes ...
Seung-Yoon Park, In-San Kim
exaly   +4 more sources

Enzymatic synthesis and decarboxylation of phosphatidylserine in Tetrahymena pyriformis [PDF]

open access: yesJournal of Lipid Research, 1970
Cell-free extracts of the protozoan Tetrahymena pyriformis have been found to catalyze the following reactions: Phosphatidylethanolamine+L-Serine⇌Phosphatidylserine+EthanolaminePhosphatidylserine→Phosphatidylethanolamine+CO2Net:L-Serine→Ethanolamine ...
EDWARD A. DENNIS, EUGENE P. KENNEDY
doaj   +2 more sources

Ebola virus requires a host scramblase for externalization of phosphatidylserine on the surface of viral particles. [PDF]

open access: yesPLoS Pathogens, 2018
Cell surface receptors for phosphatidylserine contribute to the entry of Ebola virus (EBOV) particles, indicating that the presence of phosphatidylserine in the envelope of EBOV is important for the internalization of EBOV particles.
Asuka Nanbo   +8 more
doaj   +3 more sources

Role of Calcium in Phosphatidylserine Externalisation in Red Blood Cells from Sickle Cell Patients [PDF]

open access: yesAnemia, 2011
Phosphatidylserine exposure occurs in red blood cells (RBCs) from sickle cell disease (SCD) patients and is increased by deoxygenation. The mechanisms responsible remain unclear.
Erwin Weiss   +2 more
doaj   +2 more sources

How do necrotic cells expose phosphatidylserine to attract their predators—What’s unique and what’s in common with apoptotic cells

open access: yesFrontiers in Cell and Developmental Biology, 2023
Phosphatidylserine (PS) is a lipid component of the plasma membrane. It is asymmetrically distributed to the inner leaflet in live cells. In cells undergoing apoptosis, phosphatidylserine is exposed to the outer surfaces.
Yoshitaka Furuta, Zheng Zhou
doaj   +1 more source

Conditional targeting of phosphatidylserine decarboxylase to lipid droplets

open access: yesBiology Open, 2021
Phosphatidylethanolamine is an abundant component of most cellular membranes whose physical and chemical properties modulate multiple aspects of organelle membrane dynamics. An evolutionarily ancient mechanism for producing phosphatidylethanolamine is to
Santosh Kumar   +4 more
doaj   +1 more source

Genetically encoded phosphatidylserine biosensor for in vitro, ex vivo and in vivo labelling

open access: yesCellular & Molecular Biology Letters, 2023
Background The dynamics of phosphatidylserine in the plasma membrane is a tightly regulated feature of eukaryotic cells. Phosphatidylserine (PS) is found preferentially in the inner leaflet of the plasma membrane.
Eimina Dirvelyte   +7 more
doaj   +1 more source

Pathogenic Variants in ABHD16A Cause a Novel Psychomotor Developmental Disorder With Spastic Paraplegia

open access: yesFrontiers in Neurology, 2021
Introduction: Hereditary spastic paraplegia is a clinically and genetically heterogeneous neurological entity that includes more than 80 disorders which share lower limb spasticity as a common feature.
Ashraf Yahia   +38 more
doaj   +1 more source

Osh6 Revisited: Control of PS Transport by the Concerted Actions of PI4P and Sac1 Phosphatase

open access: yesFrontiers in Molecular Biosciences, 2021
Osh6, a member of the oxysterol-binding protein–related protein (ORP) family, is a lipid transport protein that is involved in the transport of phosphatidylserine (PS) between the endoplasmic reticulum (ER) and the plasma membrane (PM).
Andrea Eisenreichova   +3 more
doaj   +1 more source

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