Results 1 to 10 of about 110,140 (293)

DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown [PDF]

open access: yes, 2011
Damage-associated molecular patterns (DAMPs) or cell death associated molecular patterns (CDAMPs) are a subset of endogenous intracellular molecules that are normally hidden within living cells but become either passively released by primary and ...
Agostinis, Patrizia   +3 more
core   +1 more source

The Tip of the Four N-Terminal α-Helices of Clostridium sordellii Lethal Toxin Contains the Interaction Site with Membrane Phosphatidylserine Facilitating Small GTPases Glucosylation

open access: yesToxins, 2016
Clostridium sordellii lethal toxin (TcsL) is a powerful virulence factor responsible for severe toxic shock in man and animals. TcsL belongs to the large clostridial glucosylating toxin (LCGT) family which inactivates small GTPases by glucosylation with ...
Carolina Varela Chavez   +7 more
doaj   +1 more source

Effects of Growth Temperatures on the Fatty Acid Composition of Isolated Chloroplasts From Two Species Differing in Heat Sensitivity [PDF]

open access: yes, 1985
Lipid analyses of chloroplasts isolated from wheat (Triticum aestivum L. cv. Arthur) and milo (Sorghum bicolor cv. Funk\u27s hybrid 522) suggest no major heat effect on lipid class distribution.
Gehring, Roy Z., Todd, Glenn W.
core   +2 more sources

Dynamics of phagocytosis mediated by phosphatidylserine

open access: yesBiochemical Society Transactions, 2022
Phagocytosis triggered by the phospholipid phosphatidylserine (PS) is key for the removal of apoptotic cells in development, tissue homeostasis and infection. Modulation of PS-mediated phagocytosis is an attractive target for therapeutic intervention in the context of atherosclerosis, neurodegenerative disease, and cancer.
openaire   +2 more sources

Induction of Suicidal Erythrocyte Death by Cantharidin

open access: yesToxins, 2015
The natural phosphoprotein phosphatase inhibitor cantharidin, primarily used for topical treatment of warts, has later been shown to trigger tumor cell apoptosis and is thus considered for the treatment of malignancy. Similar to apoptosis of tumor cells,
Kousi Alzoubi   +5 more
doaj   +1 more source

Mitochondrial apoptosis induced by Chamaemelum nobile extract in breast cancer cells [PDF]

open access: yes, 2016
Chamaemelum nobile (Asteraceae) commonly known as ‹Roman chamomile› is a medicinal plant used for numerous diseases in traditional medicine, although its anticancer activity is unknown.
Amanzadeh, A.   +5 more
core  

Use of autoantigen-loaded phosphatidylserine-liposomes to arrest autoimmunity in type 1 diabetes [PDF]

open access: yes, 2015
This is an open access article distributed under the terms of the Creative Commons Attribution License.-- et al.[Introduction]: The development of new therapies to induce self-tolerance has been an important medical health challenge in type 1 diabetes ...
Cano-Sarabia, Mary   +3 more
core   +1 more source

Quantification and a Molecular Dynamics Study of Viral Membrane Lipids through Plasmon Coupling Microscopy [PDF]

open access: yes, 2015
Phosphatidylserine (PS) and monosialotetrahexosylganglioside (G_M1) are examples of two host-derived lipids in the membrane of enveloped virus particles that are known to contribute to virus attachment, uptake, and ultimately dissemination.
Feizpour, Amin, Reinhard, Björn
core   +1 more source

Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission. [PDF]

open access: yes, 2005
Galectins have emerged as a novel family of immunoregulatory proteins implicated in T cell homeostasis. Recent studies showed that galectin-1 (Gal-1) plays a key role in tumor-immune escape by killing antitumor effector T cells.
Ascione, Barbara   +7 more
core   +1 more source

Aminoglycoside induces RIPOR2 translocation and phosphatidylserine externalization via distinct mechanisms

open access: yesFrontiers in Cellular Neuroscience
Aminoglycosides are widely used to treat severe infections. However, systemically administered AGs preferentially kill cochlear hair cells, resulting in irreversible hearing loss. Recently, we found that AGs induce a rapid translocation of RIPOR2 in hair
Jinan Li   +4 more
doaj   +1 more source

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