Results 11 to 20 of about 79,638 (253)

Graph-Based Analyses of Dynamic Water-Mediated Hydrogen-Bond Networks in Phosphatidylserine: Cholesterol Membranes [PDF]

, 2023
Phosphatidylserine lipids are anionic molecules present in eukaryotic plasma membranes, where they have essential physiological roles. The altered distribution of phosphatidylserine in cells such as apoptotic cancer cells, which, unlike healthy cells ...
Konstantina Karathanou, Jain, Honey, Karathanou, Konstantina, Ana-Nicoleta Bondar, Honey Jain, Bondar, Ana-Nicoleta   +5 more
core   +2 more sources

Circulating Microparticles in the Pathogenesis and Early Anticoagulation of Thrombosis in COVID-19 With Kidney Injury

Frontiers in Cell and Developmental Biology, 2022
As more is learned about the pathophysiological mechanisms of COVID-19, systemic thrombosis has been recognized as being associated with more severe clinical manifestations, mortality and sequelae.
Chengyue Wang, Chengyue Wang, Chengyuan Yu, Chengyuan Yu, Valerie A. Novakovic, Rujuan Xie, Jialan Shi, Jialan Shi, Jialan Shi   +8 more
doaj   +1 more source

Novel engineered chimeric engulfment receptors trigger T cell effector functions against SIV-infected CD4+ T cells

Molecular Therapy: Methods & Clinical Development, 2023
Adoptive therapy with genetically engineered T cells offers potential for infectious disease treatment in immunocompromised persons. HIV/simian immunodeficiency virus (SIV)-infected cells express phosphatidylserine (PS) early post infection.
Daniel Corey, Francoise Haeseleer, Joe Hou, Lawrence Corey   +3 more
doaj   +1 more source

Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo [PDF]

, 2004
Strategies to enhance the immunogenicity of tumors are urgently needed. Although vaccination with irradiated dying lymphoma cells recruits a tumor-specific immune response, its efficiency as immunogen is poor.
Zimmermann, VS, Voll, Reinhard E., Turnay, Javier, Manfredi, Angelo A., Turnay, J, Dumitriu, IE, Voll, RE, Zimmermann, Valérie S, Angelo A. Manfredi, Bertling, Wolf, Rovere-Querini, P, Kalden, JR, Udo S. Gaipl, Herrmann, M, Attilio Bondanza, Gaipl, Udo S, Wolf Bertling, Bertling, W, Patrizia Rovere-Querini, Ingrid E. Dumitriu, Bondanza, Attilio, Stach, Christian M., Pöschl, E, Stach, Christian M, Gaipl, US, Javier Turnay, Herrmann, Martin, Martin Herrmann, Dumitriu, Ingrid E., Rovere-Querini, Patrizia, Christian M. Stach, Manfredi, Angelo A, Kalden, Joachim R, Valérie S. Zimmermann, Pöschl, Ernst, Stach, CM, Dumitriu, Ingrid E; id_orcid, Gaipl, Udo S., Joachim R. Kalden, Bondanza, A, Zimmermann, Valérie S., Voll, Reinhard E, Kalden, Joachim R., Reinhard E. Voll, Manfredi, AA, Ernst Pöschl, Dumitriu IE, Kalden JR, Bertling W, Turnay J, Herrmann M., Poschl E, Zimmermann VS, Gaipl US, Stach CM, Voll RE, BONDANZA , ATTILIO, ROVERE QUERINI , PATRIZIA, MANFREDI , ANGELO ANDREA M. A.   +58 more
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ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia

Haematologica, 2016
Phosphatidylserine is localized exclusively to the inner leaflet of the membrane lipid bilayer of most cells, including erythrocytes. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized ...
Nobuto Arashiki, Yuichi Takakuwa, Narla Mohandas, John Hale, Kenichi Yoshida, Hiromi Ogura, Taiju Utsugisawa, Shouichi Ohga, Satoru Miyano, Seishi Ogawa, Seiji Kojima, Hitoshi Kanno   +11 more
doaj   +1 more source

Phosphatidylserine decarboxylase from Clostridium butyricum.

Journal of Lipid Research, 1985
Phosphatidylserine decarboxylase activity has been characterized in membrane preparations from Clostridium butyricum ATCC 19398. A particulate fraction was shown to catalyze the formation of phosphatidylethanolamine and plasmenylethanolamine when ...
J N Verma, H Goldfine
doaj   +1 more source

Glu- and Lys-forms of plasminogen differentially affect phosphatidylserine exposure on the platelet surface [PDF]

, 2017
Plasminogen/plasmin system is known for its ability to support hemostatic balance of blood. However, plasminogen may be considered as an adhesive ligand and in this way could affect the functioning of blood cells. We showed that exogenous Lys-plasminogen,
Zhernossekov, D.D., T. V. Grinenko, D. D. Zhernossekov, M. M. Guzyk, A. O. Tykhomyrov, Roka-Moiia, Y.M., Guzyk, M.M., Y. M. Roka-Moiia, Grinenko, T.V., Tykhomyrov, A.O.   +9 more
core   +1 more source

New sensitive assay for phosphatidylserine decarboxylase based on the detection of CO2 from nonradiolabeled phosphatidylserine [PDF]

, 1973
A new rapid assay for phosphatidylserine decarboxylase, which is sensitive in the nanomolar range, is described. Synthesis of radiolabeled phosphatidylserine for use as a substrate is not required, since the assay, unlike previous ones, is based on the ...
Warner, Thomas G, Dennis, Edward A, Edward A. Dennis, Thomas G. Warner   +3 more
core   +1 more source

Role of Phosphatidylserine Receptors in Enveloped Virus Infection [PDF]

, 2014
We recently demonstrated that a soluble protein, Gas6, can facilitate viral entry by bridging viral envelope phosphatidylserine to Axl, a receptor tyrosine kinase expressed on target cells.
Kouki Morizono, Chen, Irvin SY, Morizono, Kouki, Irvin S. Y. Chen   +3 more
core   +1 more source

A Multi-Center, Open-Label Exploratory Study to Assess Cognitive Function Response to Lifestyle Changes Plus Supplementation in Healthy Adults with Risk Factors Associated with Cognitive Decline

Applied Sciences, 2023
PreCODE is a multifaceted protocol that applies lifestyle modifications to improve cognitive decline. NeuroQ is a blend of ingredients that have been individually reported to benefit cognition.
Erin D. Lewis, Margaret Apostol, Jamie Langston, Alex Parker, Malkanthi Evans   +4 more
doaj   +1 more source