Enzymatic synthesis and decarboxylation of phosphatidylserine in Tetrahymena pyriformis [PDF]
Journal of Lipid Research, 1970 Cell-free extracts of the protozoan Tetrahymena pyriformis have been found to catalyze the following reactions: Phosphatidylethanolamine+L-Serine⇌Phosphatidylserine+EthanolaminePhosphatidylserine→Phosphatidylethanolamine+CO2Net:L-Serine→Ethanolamine ...
EDWARD A. DENNIS, EUGENE P. KENNEDY
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Role of Calcium in Phosphatidylserine Externalisation in Red Blood Cells from Sickle Cell Patients [PDF]
Anemia, 2011 Phosphatidylserine exposure occurs in red blood cells (RBCs) from sickle cell disease (SCD) patients and is increased by deoxygenation. The mechanisms responsible remain unclear.
Erwin Weiss +2 more
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On the coordination of La3+ by phosphatidylserine [PDF]
Biophysical Journal, 1989 In a recent study by Bentz, J., D. Alford, J. Cohen, and N. Düzgünes (1988. Biophys. J. 53:593-607), La3+ was found to be more effective than Ca2+ in causing nonleaky fusion of phosphatidylserine vesicles. It was proposed that this difference in fusion efficiency may be due, in part, to a difference in coordination of the two cations. That is, Ca2+ was
Petersheim, M., Sun, J.
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Molecular Therapy: Methods & Clinical Development, 2023 Adoptive therapy with genetically engineered T cells offers potential for infectious disease treatment in immunocompromised persons. HIV/simian immunodeficiency virus (SIV)-infected cells express phosphatidylserine (PS) early post infection.
Daniel Corey +3 more
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Phosphatidylserine, a death knell [PDF]
Cell Death & Differentiation, 2001 Virtually every cell in the body restricts phosphatidylserine (PS) to the inner leaflet of the plasma membrane by energy-dependent transport from the outer to the inner leaflet of the bilayer. Apoptotic cells of all types rapidly randomize the asymmetric distribution, bringing PS to the surface where it serves as a signal for phagocytosis.
R A, Schlegel, P, Williamson
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Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo [PDF]
, 2004 Strategies to enhance the immunogenicity of tumors are urgently needed. Although vaccination with irradiated dying lymphoma cells recruits a tumor-specific immune response, its efficiency as immunogen is poor.
Zimmermann, VS +45 more
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Phosphatidylserine-containing liposomes: Therapeutic potentials against hypercholesterolemia and atherosclerosis [PDF]
, 2021 Phosphatidylserine-containing liposomes: Therapeutic potentials against hypercholesterolemia and ...
Shiva Ganjali (14682088) +5 more
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ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia
Haematologica, 2016 Phosphatidylserine is localized exclusively to the inner leaflet of the membrane lipid bilayer of most cells, including erythrocytes. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized ...
Nobuto Arashiki +11 more
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Phosphatidylserine decarboxylase from Clostridium butyricum.
Journal of Lipid Research, 1985 Phosphatidylserine decarboxylase activity has been characterized in membrane preparations from Clostridium butyricum ATCC 19398. A particulate fraction was shown to catalyze the formation of phosphatidylethanolamine and plasmenylethanolamine when ...
J N Verma, H Goldfine
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Glu- and Lys-forms of plasminogen differentially affect phosphatidylserine exposure on the platelet surface [PDF]
, 2017 Plasminogen/plasmin system is known for its ability to support hemostatic balance of blood. However, plasminogen may be considered as an adhesive ligand and in this way could affect the functioning of blood cells. We showed that exogenous Lys-plasminogen,
Zhernossekov, D.D. +9 more
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