Results 1 to 10 of about 85,741 (244)

Intracellular sites of lipid synthesis and the biogenesis of mitochondria

Journal of Lipid Research, 1972
Experimental data are presented on the intracellular localization in rat liver of three enzymes which are involved in the biosynthesis of phosphatidylethanolamine and diphosphatidylglycerol.
Edward A. Dennis, Eugene P. Kennedy
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LC-MS/MS untargeted lipidomics uncovers placenta lipid signatures from intrahepatic cholestasis of pregnancy

Frontiers in Physiology
Aims: Intrahepatic cholestasis of pregnancy (ICP) stands as the predominant liver disorder affecting pregnant women, with a prevalence ranging from 0.2% to 15.6%.
Liling Xiong, Mi Tang, Hong Liu, Jianghui Cai, Ying Jin, Cheng Huang, Shasha Xing, Xiao Yang   +7 more
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Shotgun Lipidomics Revealed Altered Profiles of Serum Lipids in Systemic Lupus Erythematosus Closely Associated with Disease Activity

Biomolecules, 2018
The pathogenesis of systemic lupus erythematosus (SLE) remains elusive. It appears that serum lipid metabolism is aberrant in SLE patients. Determination of lipid profiles in the serum of SLE patients may provide insights into the underlying mechanism(s)
Lu Lu, Changfeng Hu, Yanxia Zhao, Lijiao He, Jia Zhou, Haichang Li, Yu Du, Yonghua Wang, Chengping Wen, Xianlin Han, Yongsheng Fan   +10 more
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Turnover of nonessential fatty acids in cardiolipin from the rat heart

Journal of Lipid Research, 2011
Cardiolipin (CL) is a unique phospholipid (PL) found in the mitochondria of mammalian cells. CL remodeling is accompanied by turnover of its fatty acid acyl groups. Abnormalities in CL remodeling have been found in Barth's syndrome, diabetes, and obesity.
Paulin N. Wahjudi, Jennifer K. Yee, Steven R. Martinez, Jin Zhang, Michael Teitell, Liana Nikolaenko, Ronald Swerdloff, Christina Wang, W.N. Paul Lee   +8 more
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Loss of the Major Phosphatidylserine or Phosphatidylethanolamine Flippases Differentially Affect Phagocytosis

Frontiers in Cell and Developmental Biology, 2020
The lipids phosphatidylserine (PtdSer) and phosphatidylethanolamine (PtdEth) are normally asymmetrically localized to the cytosolic face of membrane bilayers, but can both be externalized during diverse biological processes, including cell division, cell
Gholamreza Fazeli, Gholamreza Fazeli, Katharina B. Beer, Michaela Geisenhof, Sarah Tröger, Julia König, Thomas Müller-Reichert, Ann M. Wehman, Ann M. Wehman   +8 more
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Enzymatic measurement of phosphatidylserine in cultured cells

Journal of Lipid Research, 2012
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid involved in diverse cellular functions. In this study, we developed a new fluorometric method for measuring PS using combinations of specific enzymes and Amplex Red.
Shin-ya Morita, Sachimi Shirakawa, Yukiko Kobayashi, Keiko Nakamura, Reiko Teraoka, Shuji Kitagawa, Tomohiro Terada   +6 more
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N-aldehyde-modified phosphatidylethanolamines generated by lipid peroxidation are robust substrates of N-acyl phosphatidylethanolamine phospholipase D

Journal of Lipid Research
N-acyl phosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD) hydrolyzes phosphatidylethanolamines (PEs) where the headgroup nitrogen has been enzymatically modified with acyl chains of four carbons or longer (N-acyl-PEs or NAPEs).
Reza Fadaei, Annie C. Bernstein, Andrew N. Jenkins, Allison G. Pickens, Jonah E. Zarrow, Abdul-Musawwir Alli-Oluwafuyi, Keri A. Tallman, Sean S. Davies   +7 more
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PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species

Advanced Science
Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is a key driver of ferroptosis in retinal pigment epithelial (RPE) cells, a process closely associated with age‐related macular degeneration (AMD).
Zhiyang Chen, Xiaoman Zhu, Michael Mingze Lu, Qingjian Ou, Xueying Wang, Zhenzhen Zhao, Qi Shen, Qian Wang, Zhe Wang, Jing‐Ying Xu, Caixia Jin, Furong Gao, Juan Wang, Jingfa Zhang, Jieping Zhang, Xiaoliang Jin, Yanlong Bi, Lixia Lu, Guo‐Tong Xu, Haibin Tian   +19 more
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Localization of the PE methylation pathway and SR-BI to the canalicular membrane

Journal of Lipid Research, 2003
To better understand the regulation of biliary phospholipid and cholesterol excretion, canalicular membranes were isolated from the livers of C57BL/6J mice and abundant proteins separated by SDS-PAGE and identified by matrix-assisted laser desorption ...
Ephraim Sehayek, Rong Wang, Jennie G. Ono, Vadim S. Zinchuk, Elizabeth M. Duncan, Sarah Shefer, Dennis E. Vance, Meenakshisundaram Ananthanarayanan, Brian T. Chait, Jan L. Breslow   +9 more
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Phosphatidylethanolamine: A key player in lung disease

Clinical and Translational Discovery
Phosphatidylethanolamine (PE) is a pivotal glycerophospholipid that constitutes a significant portion of cellular membranes, playing a crucial role in maintaining membrane fluidity, supporting protein integration, and mediating signal transduction.
Linlin Zhang, Wanxin Duan, Liyang Li
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