Results 11 to 20 of about 82,133 (342)

Phosphatidylethanolamine positively regulates autophagy and longevity [PDF]

Cell Death & Differentiation, 2015
Autophagy is a cellular recycling program that retards ageing by efficiently eliminating damaged and potentially harmful organelles and intracellular protein aggregates. Here, we show that the abundance of phosphatidylethanolamine (PE) positively regulates autophagy.
Rockenfeller, P., Koska, M., Pietrocola, F., Minois, N., Knittelfelder, O., Sica, V., Franz, J., Carmona-Gutierrez, D., Kroemer, G., Madeo, F.   +9 more
openaire   +6 more sources

Phosphatidylethanolamine and Lysophosphatidylethanolamine

Journal of Pharmacy and Pharmacology, 1963
Abstract Phosphatidylethanolamine and Lysophosphatidylethanolamine belong to a group of phospholipids generally termed cephalins. The phospholipids are universally distributed among living organisms and are thought to be essential components of cell membranes.
D C Robins
openaire   +3 more sources

Membranes linked by trans-SNARE complexes require lipids prone to non-bilayer structure for progression to fusion

eLife, 2014
Like other intracellular fusion events, the homotypic fusion of yeast vacuoles requires a Rab GTPase, a large Rab effector complex, SNARE proteins which can form a 4-helical bundle, and the SNARE disassembly chaperones Sec17p and Sec18p.
Michael Zick, Christopher Stroupe, Amy Orr, Deborah Douville, William T Wickner   +4 more
doaj   +1 more source

Skeletal Muscle Consequences of Phosphatidylethanolamine Synthesis Deficiency

Function, 2023
The maintenance of phospholipid homeostasis is increasingly being implicated in metabolic health. Phosphatidylethanolamine (PE) is the most abundant phospholipid on the inner leaflet of cellular membranes, and we have previously shown that mice with a ...
Sophie Grapentine, Rathnesh K Singh, Marica Bakovic   +2 more
doaj   +1 more source

Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5′-phosphate as the inhibitor

Journal of Lipid Research, 2006
Peroxidized phospholipid-mediated cytotoxity is involved in the pathophysiology of a number of diseases [i.e., the abnormal increase of phosphatidylcholine hydroperoxide (PCOOH) found in the plasma of type 2 diabetic patients]. The PCOOH accumulation may
Ohki Higuchi, Kiyotaka Nakagawa, Tsuyoshi Tsuzuki, Toshihide Suzuki, Shinichi Oikawa, Teruo Miyazawa   +5 more
doaj   +1 more source

Membrane phospholipid redistribution in cancer micro-particles and implications in the recruitment of cationic protein factors

Journal of Extracellular Vesicles, 2014
Cancer cell-derived micro-particles (MPs) play important regulatory roles on cellular and system levels. These activities are attributed in part to protein factors carried by MPs.
Songwang Hou, Doris Grillo, Carol L. Williams, J. Andrew Wasserstrom, Igal Szleifer, Ming Zhao   +5 more
doaj   +1 more source

Phosphatidylethanolamine Levels and Regulation of Phosphatidylethanolamine N- Methyltransferase

Journal of Biological Chemistry, 1989
The activity of phosphatidylethanolamine (PE) N-methyltransferase in liver microsomes, measured using endogenous microsomal PE as a substrate, was elevated 2-fold in the choline-deficient state. However, methyltransferase activity assayed in the presence of a saturating concentration of phosphatidyl-N-mono-methylethanolamine or microsomal PE was ...
N D, Ridgway, Z, Yao, D E, Vance
openaire   +2 more sources

Serum phospholipids during aging: A comprehensive systematic review of cross-sectional and case-control studies [PDF]

Health Promotion Perspectives
Background: The lipidome, as a subset of metabolomics, can undergo significant variations due to several factors, including the aging process. Therefore, this study aims to summarize the relationship between aging and alterations in plasma phospholipids.
Meysam Zarezadeh, Mahsa Mahmoudinezhad, Amir Hossein Faghfouri, Nima Radkhah, Mehrdad Jamali, Parsa Jamilian, Zohreh Ghoreyshi, Alireza Ostadrahimi   +7 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

PEBP1 (phosphatidylethanolamine binding protein 1) [PDF]

, 2008
Review on PEBP1 (phosphatidylethanolamine binding protein 1), with data on DNA, on the protein encoded, and where the gene is ...
Beach, S, Yeung, KC
core   +1 more source