Results 11 to 20 of about 105,655 (290)

Phosphatidylethanolamine Levels and Regulation of Phosphatidylethanolamine N- Methyltransferase

Journal of Biological Chemistry, 1989
The activity of phosphatidylethanolamine (PE) N-methyltransferase in liver microsomes, measured using endogenous microsomal PE as a substrate, was elevated 2-fold in the choline-deficient state. However, methyltransferase activity assayed in the presence of a saturating concentration of phosphatidyl-N-mono-methylethanolamine or microsomal PE was ...
N D, Ridgway, Z, Yao, D E, Vance
openaire   +2 more sources

Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5′-phosphate as the inhibitor

Journal of Lipid Research, 2006
Peroxidized phospholipid-mediated cytotoxity is involved in the pathophysiology of a number of diseases [i.e., the abnormal increase of phosphatidylcholine hydroperoxide (PCOOH) found in the plasma of type 2 diabetic patients]. The PCOOH accumulation may
Ohki Higuchi, Kiyotaka Nakagawa, Tsuyoshi Tsuzuki, Toshihide Suzuki, Shinichi Oikawa, Teruo Miyazawa   +5 more
doaj   +1 more source

Membrane phospholipid redistribution in cancer micro-particles and implications in the recruitment of cationic protein factors

Journal of Extracellular Vesicles, 2014
Cancer cell-derived micro-particles (MPs) play important regulatory roles on cellular and system levels. These activities are attributed in part to protein factors carried by MPs.
Songwang Hou, Doris Grillo, Carol L. Williams, J. Andrew Wasserstrom, Igal Szleifer, Ming Zhao   +5 more
doaj   +1 more source

Serum phospholipids during aging: A comprehensive systematic review of cross-sectional and case-control studies [PDF]

Health Promotion Perspectives
Background: The lipidome, as a subset of metabolomics, can undergo significant variations due to several factors, including the aging process. Therefore, this study aims to summarize the relationship between aging and alterations in plasma phospholipids.
Meysam Zarezadeh, Mahsa Mahmoudinezhad, Amir Hossein Faghfouri, Nima Radkhah, Mehrdad Jamali, Parsa Jamilian, Zohreh Ghoreyshi, Alireza Ostadrahimi   +7 more
doaj   +1 more source

A rapid phospholipase D assay using zirconium precipitation of anionic substrate phospholipids: application to N-acylethanolamine formation in vitro

Journal of Lipid Research, 2000
Activation of phospholipase D (PLD) is involved in a number of signal transduction pathways in eukaryotic cells. The most common method for determination of PLD activity in vitro involves incubation with a radiolabeled substrate and lipid extraction ...
Gitte Petersen, Kent D. Chapman, Harald S. Hansen   +2 more
doaj   +1 more source

ExoS/ChvI Two-Component Signal-Transduction System Activated in the Absence of Bacterial Phosphatidylcholine

Frontiers in Plant Science, 2021
Sinorhizobium meliloti contains the negatively charged phosphatidylglycerol and cardiolipin as well as the zwitterionic phosphatidylethanolamine (PE) and phosphatidylcholine (PC) as major membrane phospholipids.
Otto Geiger, Christian Sohlenkamp, Diana Vera-Cruz, Daniela B. Medeot, Lourdes Martínez-Aguilar, Diana X. Sahonero-Canavesi, Stefan Weidner, Alfred Pühler, Isabel M. López-Lara   +8 more
doaj   +1 more source

The interaction of amyloid A beta(1-40) with lipid bilayers and ganglioside as studied by P-31 solid-state NMR [PDF]

, 2009
Amyloid P-peptide (A beta) is a major component of plaques in Alzheimer's disease, and formation of senile plaques has been suggested to originate fro m regions of neuronal membrane rich in gangliosides. We analyzed the mode of interaction of A beta with
Asakura, T., Nakazawa, Y., Saito, H., Suzuki, Y., Williamson, M.P.   +4 more
core   +1 more source

Enzymatic synthesis and decarboxylation of phosphatidylserine in Tetrahymena pyriformis

Journal of Lipid Research, 1970
Cell-free extracts of the protozoan Tetrahymena pyriformis have been found to catalyze the following reactions: Phosphatidylethanolamine+L-Serine⇌Phosphatidylserine+EthanolaminePhosphatidylserine→Phosphatidylethanolamine+CO2Net:L-Serine→Ethanolamine ...
EDWARD A. DENNIS, EUGENE P. KENNEDY
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source