Results 21 to 30 of about 105,655 (290)

Positional specificity of lysosomal phospholipase A2

Journal of Lipid Research, 2006
Lysosomal phospholipase A2 (Lpla2) is highly expressed in alveolar macrophages and may mediate the phospholipid metabolism of surfactant. Studies on the properties of this phospholipase are consistent with the presence of both phospholipase A1 and ...
Akira Abe, Miki Hiraoka, James A. Shayman   +2 more
doaj   +1 more source

Canine NAPEPLD-associated models of human myelin disorders [PDF]

, 2018
Canine leukoencephalomyelopathy (LEMP) is a juvenile-onset neurodegenerative disorder of the CNS white matter currently described in Rottweiler and Leonberger dogs. Genome-wide association study (GWAS) allowed us to map LEMP in a Leonberger cohort to dog
Bannasch, D L, Becker, D, Bellekom, S R, Cassidy, J P, Drogemuller, C, Drogemuller, M, Ekenstedt, K J, Fischer, A, Flegel, T, Furrow, E, Henke, D, Jagannathan, V, Kelly, P A, Leegwater, P A J, Letko, A, Lucot, K, Mandigers, P J J, Martineau, H, Matiasek, K, Mickelson, J R, Minor, K M, Muir, C F, Oevermann, A, Patterson, E E, Platt, S R, Priestnall, S L, Putschbach, K, Shelton, G D, Stassen, QEM   +28 more
core   +7 more sources

Duramycin-induced calcium release in cancer cells [PDF]

, 2015
Introduction: Duramycin through binding with phosphatidylethanolamine (PE) has shown potential to be an effective anti-tumour agent. However its mode of action in relation to tumour cells is not fully understood.
Broughton, Laura J., Crow, Chris, Madden, Leigh A., Maraveyas, Anthony   +3 more
core   +1 more source

PS, It’s Complicated: The Roles of Phosphatidylserine and Phosphatidylethanolamine in the Pathogenesis of Candida albicans and Other Microbial Pathogens

Journal of Fungi, 2018
The phospholipids phosphatidylserine (PS) and phosphatidylethanolamine (PE) play important roles in the virulence of Candida albicans and loss of PS synthesis or synthesis of PE from PS (PS decarboxylase) severely compromises virulence in C.
Chelsi D. Cassilly, Todd B. Reynolds
doaj   +1 more source

Phosphatidylethanolamine positively regulates autophagy and longevity [PDF]

Cell Death & Differentiation, 2015
Autophagy is a cellular recycling program that retards ageing by efficiently eliminating damaged and potentially harmful organelles and intracellular protein aggregates. Here, we show that the abundance of phosphatidylethanolamine (PE) positively regulates autophagy.
Rockenfeller, P., Koska, M., Pietrocola, F., Minois, N., Knittelfelder, O., Sica, V., Franz, J., Carmona-Gutierrez, D., Kroemer, G., Madeo, F.   +9 more
openaire   +5 more sources

Identification and characterization of human ethanolaminephosphotransferase1

Journal of Lipid Research, 2007
CDP-ethanolamine:diacylglycerol ethanolaminephosphotransferase (EPT) catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine (PE).
Yasuhiro Horibata, Yoshio Hirabayashi
doaj   +1 more source

Thermotomaculum hydrothermale gen. nov., sp. nov., a novel heterotrophic thermophile within the phylum Acidobacteria from a deep-sea hydrothermal vent chimney in the Southern Okinawa Trough [PDF]

, 2012
http://www.godac.jamstec.go.jp/darwin/cruise/natsushima/nt08-13/
A-L Reysenbach, CM Santelli, DA Bryant, DB Meisinger, DE Minnikin, DJ Lane, DL Swofford, H Imachi, H Kampe, Hiroshi Izumi, IH Koch, IS Kulichevskaya, J Sambrook, J Tamaoka, J Tamaoka, J Zimmermann, JA Baross, JD Coates, K Komagata, K Takai, Ken Takai, KG Porter, M Sait, Masayuki Miyazaki, MB Stott, N Kishimoto, N Saitou, NL Ward, P Hugenholtz, P López-García, S Kleinsteuber, S Nakagawa, S Nakagawa, S Nakagawa, S Nakagawa, SA Eichorst, Satoshi Nakagawa, Sayaka Mino, SF Altschul, SM Barns, SM Barns, SM Sievert, T Nunoura, T Nunoura, T Nunoura, TA Pankratov, Takuro Nunoura, TH Jukes, Tomohiro Toki, Tomoo Sawabe, W Liesack, W Ludwig, W Ludwig, W Zillig, WJ Brazelton, Y Fukunaga, Y Sako, Yoshihiko Sako   +57 more
core   +1 more source

Implications of mitochondrial phosphatidylethanolamine in neuronal health and neurodegeneration

Neural Regeneration Research
Phosphatidylethanolamine is a major phospholipid class abundant in the brain, particularly in the inner leaflet of the plasma and mitochondrial membranes. Although it is primarily synthesized from phosphatidylserine via decarboxylation in mitochondria or
Yantao Zuo, Niharika Amireddy, Qian Cai
doaj   +1 more source

Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain

Journal of Lipid Research, 2008
Anandamide is an endogenous signaling lipid that binds to and activates cannabinoid receptors in the brain and peripheral tissues. The endogenous precursors of ananda­mide, N-arachidonoyl phosphatidylethanolamines (NArPEs), are a family of complex ...
Giuseppe Astarita, Faizy Ahmed, Daniele Piomelli   +2 more
doaj   +1 more source

Lipidomics Reveals Early Metabolic Changes in Subjects with Schizophrenia: Effects of Atypical Antipsychotics [PDF]

, 2013
There is a critical need for mapping early metabolic changes in schizophrenia to capture failures in regulation of biochemical pathways and networks.
AA Farooqui, AI Glen, BE Leonard, C Luo, D Cohen, DF Horrobin, DF Horrobin, DP Rice, George G. Dougherty, GP Amminger, Henry A. Nasrallah, HM Rhoades, Hongjie Zhu, Jeffrey K. Yao, JJ Potwarka, JK Yao, JK Yao, JM Kane, Joseph McEvoy, JP McEvoy, JR Hibbeln, K Ohara, KS Dervola, M Arvindakshan, M McSweeney, M Peet, M Strassnig, M Zeman, Matcheri S. Keshavan, MK Gregory, MS Keshavan, MS Keshavan, MS Keshavan, Peter Buckley, R Kaddurah-Daouk, R Kaddurah-Daouk, RA Johnson, RD McQuade, Rebecca A. Baillie, Rima Kaddurah-Daouk, S Mukherjee, S Saddichha, S Sengupta, SH Fatemi, SJ Wood, SM Watkins, SM Watkins, SP Mahadik, T Sumiyoshi, Takeo Yoshikawa, TJ Barrett, TM du Bois, WJ van der Kemp, WP Hoen, Y Benjamini, Y Benjamini, YA Hannun   +56 more
core   +8 more sources