Results 31 to 40 of about 79,638 (253)

Helicobacter pylori cholesterol-α-glucosyltransferase manipulates cholesterol for bacterial adherence to gastric epithelial cells

Virulence, 2021
Helicobacter pylori infection is associated with several gastrointestinal diseases, including gastritis, peptic ulcers, and gastric cancer. Infection of cells with H.
Chung-Yao Hsu, Jia-Yin Yeh, Chun-Ya Chen, Hui-Yu Wu, Meng-Hsuan Chiang, Chia-Lin Wu, Hwai-Jeng Lin, Cheng-Hsun Chiu, Chih-Ho Lai   +8 more
doaj   +1 more source

Phosphatidylserine-dependent structure of synaptogyrin remodels the synaptic vesicle membrane [PDF]

, 2023
Synaptic vesicles are small membrane-enclosed organelles that store neurotransmitters at presynaptic terminals. The uniform morphology of synaptic vesicles is important for brain function, because it enables the storage of well-defined amounts of ...
Becker, Stefan, Zweckstetter, Markus, Yu, Taekyung, Zweckstetter, M., Eastep, Gunnar N., Flores-Solis, David, Becker, S., Eastep, G., Flores-Solis, D., Yu, T.   +9 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Induction of Suicidal Erythrocyte Death by Nelfinavir

Toxins, 2015
The HIV protease inhibitor, nelfinavir, primarily used for the treatment of HIV infections, has later been shown to be effective in various infectious diseases including malaria. Nelfinavir may trigger mitochondria-independent cell death.
Rosi Bissinger, Sabrina Waibel, Florian Lang   +2 more
doaj   +1 more source

The effect of addition protein, phosphatidylcholine, phosphatidylserine, and inulin on GFAP levels of acute ischemic stroke patients at Dr. Kariadi Hospital, Semarang

Jurnal Gizi Indonesia: The Indonesian Journal of Nutrition, 2021
Background: The occurrence of ischemia causes a loss of energy to switch to anaerobic processes resulting in acidosis due to reduced Adenosina Triphosphate (ATP). This condition makes neuron cells apoptotic. Apoptotic of several biochemical substrates in
Diah Retno Wahyuningrum, Retnaningsih Retnaningsih, Martha Irene Kartasurya   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Stimulation of Erythrocyte Cell Membrane Scrambling by Mushroom Tyrosinase

Toxins, 2014
Background: Mushroom tyrosinase, a copper containing enzyme, modifies growth and survival of tumor cells. Mushroom tyrosinase may foster apoptosis, an effect in part due to interference with mitochondrial function.
Leonie Frauenfeld, Kousi Alzoubi, Majed Abed, Florian Lang   +3 more
doaj   +1 more source

Ex Vivo Activation of Red Blood Cell Senescence by Plasma from Sickle-Cell Disease Patients: Correlation between Markers and Adhesion Consequences during Acute Disease Events

Biomolecules, 2021
BACKGROUND: Blood transfusion remains a key treatment for managing occlusive episodes and painful crises in sickle-cell disease (SCD). In that clinical context, red blood cells (RBCs) from donors and transfused to patients, may be affected by plasma ...
Philippe Chadebech, Gwellaouen Bodivit, Gaétana Di Liberto, Alicia Jouard, Corinne Vasseur, France Pirenne, Pablo Bartolucci   +6 more
doaj   +1 more source

Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity. [PDF]

, 2010
We used genetically-encoded fluorescent probes to visualize the distribution of phosphatidylserine (PS) in live S. cerevisiae. The majority of the PS was found to reside in the cytosolic leaflet of the plasma membrane.
Gregory Fairn, Sergio Grinstein
core