Stimulation of Erythrocyte Cell Membrane Scrambling by Mushroom Tyrosinase
Toxins, 2014 Background: Mushroom tyrosinase, a copper containing enzyme, modifies growth and survival of tumor cells. Mushroom tyrosinase may foster apoptosis, an effect in part due to interference with mitochondrial function.
Leonie Frauenfeld +3 more
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Biomolecules, 2021 BACKGROUND: Blood transfusion remains a key treatment for managing occlusive episodes and painful crises in sickle-cell disease (SCD). In that clinical context, red blood cells (RBCs) from donors and transfused to patients, may be affected by plasma ...
Philippe Chadebech +6 more
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Phosphatidylserine hide-and-seek [PDF]
Proceedings of the National Academy of Sciences, 2018 Every day, billions of new cells are produced in our bodies, and an equivalent number must die. Normally this occurs by apoptosis (1), during which the chromatin compacts against the nuclear envelope, followed rapidly by nuclear fragmentation and budding into multiple membrane-bound apoptotic bodies. This “dance of death” results from the activation of
openaire +2 more sources
Control of phosphatidylserine biosynthesis through phosphatidylserine-mediated inhibition of phosphatidylserine synthase I in Chinese hamster ovary cells [PDF]
Proceedings of the National Academy of Sciences, 1998 Phosphatidylserine (PtdSer) synthesis in Chinese hamster ovary (CHO) cells occurs through the exchange of l -serine with the base moiety of phosphatidylcholine or phosphatidylethanolamine. The synthesis is depressed on the addition of PtdSer to the culture medium.
O, Kuge +3 more
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Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity. [PDF]
, 2010 We used genetically-encoded fluorescent probes to visualize the distribution of phosphatidylserine (PS) in live S. cerevisiae. The majority of the PS was found to reside in the cytosolic leaflet of the plasma membrane.
Gregory Fairn, Sergio Grinstein
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Phosphatidylserine exposure by apoptotic cells:a phylogenetically conserved mechanism [PDF]
, 1998 Tolerance of the existence of the individual cell in multicellular organisms is mediated by the distribution of the various phospholipid species across the bilayer of the plasma membrane.
Baehrecke, Eric H. +4 more
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Research Progress on Preparation Method, Structure and Application of Phosphatidylserine Liposomes
Shipin gongye ke-jiPhosphatidylserine is an important cell membrane component, especially in animal brain nerve cells. It has many biological activities such as improving nerve cell function, regulating nerve impulse conduction and enhancing memory.
Feilong SHI +9 more
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Physiological consequences of disruption of mammalian phospholipid biosynthetic genes
Journal of Lipid Research, 2009 By 1959, Eugene Kennedy and coworkers had outlined most pathways of phospholipid biosynthesis. In the next four decades, the emphasis was on enzymology and regulation of these pathways.
Dennis E. Vance, Jean E. Vance
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