Results 1 to 10 of about 466 (146)
Feasibility of the preparation of cochleate suspensions from naturally derived phosphatidylserines [PDF]
Frontiers in Medical Technology, 2023 IntroductionCochleates are cylindrical particles composed of dehydrated phospholipid bilayers. They are typically prepared by addition of calcium ions to vesicles composed of negatively charged phospholipids such as phosphatidylserines (PS). Due to their
Judith Kuntsche
exaly +4 more sources
Diannexin Protects against Renal Ischemia Reperfusion Injury and Targets Phosphatidylserines in Ischemic Tissue [PDF]
PLoS ONE, 2011 Renal ischemia/reperfusion injury (IRI) frequently complicates shock, renal transplantation and cardiac and aortic surgery, and has prognostic significance. The translocation of phosphatidylserines to cell surfaces is an important pro-inflammatory signal
Otto Boerman +2 more
exaly +5 more sources
PLoS Pathogens, 2018 Herpes simplex virus (HSV) entry is associated with Akt translocation to the outer leaflet of the plasma membrane to promote a complex signaling cascade.
Carl Pierce, Betsy Herold
exaly +3 more sources
Decreased Hyocholic Acid and Lysophosphatidylcholine Induce Elevated Blood Glucose in a Transgenic Porcine Model of Metabolic Disease [PDF]
Metabolites, 2022 (1) Background: This work aims to investigate the metabolomic changes in PIGinH11 pigs and investigate differential compounds as potential therapeutic targets for metabolic diseases.
Jianping Xu +6 more
doaj +2 more sources
Biomolecules, 2021 The lipid composition of biomembranes influences the properties of the lipid bilayer and that of the proteins. In this study, the lipidome and the lipid/protein ratio of membranes from High Five™ insect cells overexpressing mouse P-glycoprotein was ...
Maria João Moreno +4 more
doaj +2 more sources
Toxins, 2022 Male weaned piglets n = 6/group were fed Fumonisin B1+2+3 (FBs) mycotoxins at 0, 15, or 30 mg/kg diet for 3 weeks to assess the fatty acid (FA) composition of membrane lipid classes, lipid peroxidation, and histomorphological changes in the liver and ...
Omeralfaroug Ali +5 more
doaj +2 more sources
Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death
Metabolites, 2021 Caenorhabditis elegans is well-known as the model organism used to elucidate the genetic pathways underlying the first described form of regulated cell death, apoptosis. Since then, C.
Marcos A. Perez, Jennifer L. Watts
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Plasma procoagulant phospholipid clotting time and venous thromboembolism risk
Research and Practice in Thrombosis and Haemostasis, 2021 Background Negatively charged procoagulant phospholipids, phosphatidylserine (PS) in particular, are vital to coagulation and expressed on the surface membrane of extracellular vesicles.
Cathrine Ramberg +7 more
doaj +1 more source
Phosphatidylserine in atherosclerosis [PDF]
Current Opinion in Lipidology, 2016 Purpose of review It is now widely acknowledged that phosphatidylserine is a multifunctional bioactive lipid. In this review, we focus on the function of phosphatidylserine in modulating cholesterol metabolism, influencing inflammatory response and regulating coagulation system, and discuss promising phosphatidylserine-based ...
Darabi, Maryam, Kontush, Anatol
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Phosphatidylserine, a death knell [PDF]
Cell Death & Differentiation, 2001 Virtually every cell in the body restricts phosphatidylserine (PS) to the inner leaflet of the plasma membrane by energy-dependent transport from the outer to the inner leaflet of the bilayer. Apoptotic cells of all types rapidly randomize the asymmetric distribution, bringing PS to the surface where it serves as a signal for phagocytosis.
R A, Schlegel, P, Williamson
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