Results 31 to 40 of about 466 (146)

Datasheet1_Feasibility of the preparation of cochleate suspensions from naturally derived phosphatidylserines.pdf

, 2023
IntroductionCochleates are cylindrical particles composed of dehydrated phospholipid bilayers. They are typically prepared by addition of calcium ions to vesicles composed of negatively charged phospholipids such as phosphatidylserines (PS). Due to their
Judith Kuntsche, Khadeija Hassan, Søren Kristensen (3547472), Khadeija Hassan (16936341), Frank Steiniger (1529365), Nadia Skarnager Andersen, Judith Kuntsche (2925867), Frank Steiniger, Nadia Skarnager Andersen (16936344), Søren Kristensen   +9 more
core   +1 more source

Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency

Cell Reports, 2017
Defective lysosomal function defines many neurodegenerative diseases, such as neuronal ceroid lipofuscinoses (NCL) and Niemann-Pick type C (NPC), and is implicated in Alzheimer’s disease (AD) and frontotemporal lobar degeneration (FTLD-TDP) with ...
Bret M. Evers, Carlos Rodriguez-Navas, Rachel J. Tesla, Janine Prange-Kiel, Catherine R. Wasser, Kyoung Shin Yoo, Jeffrey McDonald, Basar Cenik, Thomas A. Ravenscroft, Florian Plattner, Rosa Rademakers, Gang Yu, Charles L. White, III, Joachim Herz   +13 more
doaj   +1 more source

On the coordination of La3+ by phosphatidylserine

Biophysical Journal, 1989
In a recent study by Bentz, J., D. Alford, J. Cohen, and N. Düzgünes (1988. Biophys. J. 53:593-607), La3+ was found to be more effective than Ca2+ in causing nonleaky fusion of phosphatidylserine vesicles. It was proposed that this difference in fusion efficiency may be due, in part, to a difference in coordination of the two cations. That is, Ca2+ was
Petersheim, M., Sun, J.
openaire   +2 more sources

Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice

Lipids in Health and Disease, 2022
Background Recent findings show that extracellular vesicle constituents can exert short- and long-range biological effects on neighboring cells in the brain, opening an exciting avenue for investigation in the field of neurodegenerative diseases ...
Melissa R. Pergande, Christina Kang, Diann George, Pearl A. Sutter, Stephen J. Crocker, Stephanie M. Cologna, Maria I. Givogri   +6 more
doaj   +1 more source

Role of Annexin A1 in NLRP3 Inflammasome Activation in Murine Neutrophils

Cells, 2021
This study evaluated the role of endogenous and exogenous annexin A1 (AnxA1) in the activation of the NLRP3 inflammasome in isolated peritoneal neutrophils.
José Marcos Sanches, Rebeca D. Correia-Silva, Gustavo H. B. Duarte, Anna Maria A. P. Fernandes, Salvador Sánchez-Vinces, Patrícia O. Carvalho, Sonia M. Oliani, Karina R. Bortoluci, Vanessa Moreira, Cristiane D. Gil   +9 more
doaj   +1 more source

Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet

Journal of Lipid Research, 2021
Recent studies have highlighted an important role for lysophosphatidylcholine acyltransferase 3 (LPCAT3) in controlling the PUFA composition of cell membranes in the liver and intestine.
Thibaut Bourgeois, Antoine Jalil, Charles Thomas, Charlène Magnani, Naig Le Guern, Thomas Gautier, Jean-Paul Pais de Barros, Victoria Bergas, Hélène Choubley, Loïc Mazzeo, Louise Menegaut, Lorène Josiane Lebrun, Kévin Van Dongen, Marion Xolin, Tony Jourdan, Chloé Buch, Jérome Labbé, Philippe Saas, Laurent Lagrost, David Masson, Jacques Grober   +20 more
doaj   +1 more source

Identification of atypical ether-linked glycerophospholipid species in macrophages by mass spectrometry

Journal of Lipid Research, 2010
A large scale profiling and analysis of glycerophospholipid species in macrophages has facilitated the identification of several rare and atypical glycerophospholipid species.
Pavlina T. Ivanova, Stephen B. Milne, H. Alex Brown   +2 more
doaj   +1 more source

Changes in Lipid Profile of Keratinocytes from Rat Skin Exposed to Chronic UVA or UVB Radiation and Topical Application of Cannabidiol

Antioxidants, 2020
UV radiation is a well-established environmental risk factor known to cause oxidative stress and disrupt the metabolism of keratinocyte phospholipids. Cannabidiol (CBD) is a phytocannabinoid with anti-inflammatory and antioxidant effects.
Wojciech Łuczaj, Maria do Rosário Domingues, Pedro Domingues, Elżbieta Skrzydlewska   +3 more
doaj   +1 more source

Deciphering the role of individual acyl chains in the interaction network between phosphatidylserines and a single-spanning membrane protein.

, 2002
International audiencePMP1 is a small single-spanning membrane protein functioning as a regulatory subunit of the yeast plasma membrane H(+)-ATPase. This protein forms a unique helix and exhibits a positively charged cytoplasmic domain that is able to ...
Mousson, Florence, Baleux, Françoise, Neumann, Jean-Michel, Coïc, Yves-Marie, Beswick, Veronica, Sanson, Alain   +5 more
core   +1 more source

Lipidomics Revealed Plasma Phospholipid Profile Differences between Deceased and Recovered COVID-19 Patients

Biomolecules, 2022
Thorough understanding of metabolic changes, including lipidome alteration, associated with the development of COVID-19 appears to be crucial, as new types of coronaviruses are still reported.
Neven Žarković, Biserka Orehovec, Bruno Baršić, Marko Tarle, Marta Kmet, Ivica Lukšić, Franz Tatzber, Willibald Wonisch, Elżbieta Skrzydlewska, Wojciech Łuczaj   +9 more
doaj   +1 more source