Results 31 to 40 of about 31,210 (332)

Phosphatidylserine in atherosclerosis [PDF]

Current Opinion in Lipidology, 2016
Purpose of review It is now widely acknowledged that phosphatidylserine is a multifunctional bioactive lipid. In this review, we focus on the function of phosphatidylserine in modulating cholesterol metabolism, influencing inflammatory response and regulating coagulation system, and discuss promising phosphatidylserine-based ...
Darabi, Maryam, Kontush, Anatol
openaire   +3 more sources

Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death

Metabolites, 2021
Caenorhabditis elegans is well-known as the model organism used to elucidate the genetic pathways underlying the first described form of regulated cell death, apoptosis. Since then, C.
Marcos A. Perez, Jennifer L. Watts
doaj   +1 more source

Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR)

Scientific Reports, 2022
Evidence is mounting that the nature of the lipid bound to the endothelial cell protein C receptor (EPCR) has an impact on its biological roles, as observed in anticoagulation and more recently, in autoimmune disease.
Elena Erausquin, María Morán-Garrido, Jorge Sáiz, Coral Barbas, Gilda Dichiara-Rodríguez, Alejandro Urdiciain, Jacinto López-Sagaseta   +6 more
doaj   +1 more source

Phosphatidylserine, a death knell [PDF]

Cell Death & Differentiation, 2001
Virtually every cell in the body restricts phosphatidylserine (PS) to the inner leaflet of the plasma membrane by energy-dependent transport from the outer to the inner leaflet of the bilayer. Apoptotic cells of all types rapidly randomize the asymmetric distribution, bringing PS to the surface where it serves as a signal for phagocytosis.
R A, Schlegel, P, Williamson
openaire   +2 more sources

Lipidomic Assessment of Plasma and Placenta of Women with Early-Onset Preeclampsia [PDF]

, 2014
Introduction: Adipose tissue is responsible for triggering chronic systemic inflammatory response and these changes may be involved in the pathophysiology of preeclampsia.
Bonetti, Tatiana, Cerdeira, Ana Sofia, Câmara, Niels Olsen S., Da Silva, Ismael Dale Cotrim Guerreiro, De Oliveira, Leandro, Korkes, Henri Augusto, Moron, Antonio F., Sass, Nelson   +7 more
core   +8 more sources

Lipidomic Profiling Identifies a Novel Lipid Signature Associated with Ethnicity-Specific Disparity of Bladder Cancer

Metabolites, 2022
Bladder Cancer (BLCA) is the ninth most frequently diagnosed cancer globally and the sixth most common cancer in the US. African Americans (AA) exhibit half the BLCA incidence compared to European Americans (EA), but they have a 70% higher risk of cancer-
Karthik Reddy Kami Reddy, Danthasinghe Waduge Badrajee Piyarathna, Abu Hena Mostafa Kamal, Vasanta Putluri, Shiva Shankar Ravi, Roni J. Bollag, Martha K. Terris, Yair Lotan, Nagireddy Putluri   +8 more
doaj   +1 more source

A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife [PDF]

, 2016
Background: This pilot study assessed the diagnostic accuracy of rapid evaporative ionization mass spectrometry (REIMS) in colorectal cancer (CRC) and colonic adenomas. Methods: Patients undergoing elective surgical resection for CRC were recruited at St.
Alexander, J, Balog, J, Darzi, A, Gildea, L, Goldin, R, Hoare, J, Kinross, J, Kontovounisios, C, McKenzie, J, Muirhead, L, Nicholson, J, Rasheed, S, Scott, A, Speller, A, Takats, Z, Teare, J, Tekkis, P, Veselkov, K   +17 more
core   +1 more source

Effects of Natural Antioxidants on Phospholipid and Ceramide Profiles of 3D-Cultured Skin Fibroblasts Exposed to UVA or UVB Radiation

Antioxidants, 2021
Ultraviolet (UV) radiation is one of the primary factors responsible for disturbances in human skin cells phospholipid metabolism. Natural compounds that are commonly used to protect skin, due to their lipophilic or hydrophilic nature, show only a narrow
Agnieszka Gęgotek, Wojciech Łuczaj, Elżbieta Skrzydlewska   +2 more
doaj   +1 more source

Prospects of apoptotic cell-based therapies for transplantation and inflammatory diseases. [PDF]

, 2013
International audienceApoptotic cell removal or interactions of early-stage apoptotic cells with immune cells are associated with an immunomodulatory microenvironment that can be harnessed to exert therapeutic effects.
Ariel, Bellingan, Bournazou, Caruso, Chang, Coles, Dini, Golpon, Griffith, Hall, Huynh, Idoyaga, Ip, Kirsch, Kurosaka, Liu, Maeda, Mevorach, Paidassi, Philippe Saas, Ravishankar, Ren, Sandra Kaminski, Seitz, Shibata, Stuart, Sylvain Perruche, Tso, Wood   +28 more
core   +3 more sources

Genome wide analysis of gene expression changes in skin from patients with type 2 diabetes [PDF]

, 2020
Non-healing chronic ulcers are a serious complication of diabetes and are a major healthcare problem. While a host of treatments have been explored to heal or prevent these ulcers from forming, these treatments have not been found to be consistently ...
A Avogaro, A Gaultier, A Le Guelte, A Magli, AA Anderson, AE Rodríguez-Fraticelli, AJ Monteforte, B Shu, BG Seligman, C Ling, C Margadant, C Ozbayer, C Shi, C Tian, C Ung, C Vanderplanck, C Wu, D Bosnakovski, D Bosnakovski, D Karthik, D Lazzaro, DJ Mangelsdorf, DM D'Souza, DS Frankel, E Ansseau, E Ansseau, E Nilsson, EA Coon, EA Malt, EM Small, F Gragnano, F Guan, G Theocharidis, G. Said, GH Wong, GJ Berry, GJ Berry, GL Bellot, GV Gnoni, H Andersen, H Brem, HA Ramirez, I Bettahi, I Bettahi, I Chakroun, I Gottfried, IN Vial, J Thimmarayappa, J Xu, J Yan, JB Rice, JC Corton, JG Van Vranken, JS Hansen, K Blackburn, KM Popov, L Nasarre, L Tan, LA Berchtold, LE Reynolds, M Gupta, M Wight, MA Faghihi, MK Montgomery, MR Tanner, MR Tanner, N Schonrock, N Takagi, NY Yoshihito Nogusa, P Hebbar, P Rajendran, PJ Batista, PM Mannucci, RB Tajhya, RC Pink, RN Weijers, RS Kaplan, RS Kiss, S Baldari, S Barrientos, S Das, S Das, S Lambert, S Rovira-Llopis, S Roy, S Sethumadhavan, SM Weis, SS Kulkarni, SV Suryavanshi, SY Park, T Fujiwara, T Khalfaoui, T Thiruvoipati, T Wang, T-H Wang, TT Hien, V Iacobazzi, V Miragliotta, VV Sinyov, W Meng, WI Sivitz, WM Longmate, WM Longmate, X Shi, X Wang, X Xie, X Yuan, X Zhao, X Zhao, Y Cai, Y Carrier, Y Chen, Y Gu, Y Konishi, Y Liu, Y Wang, Y-T Chen, Y-Y Hsieh, Z Jiang, Z-X Meng, ZKK Lawi   +120 more
core   +1 more source