Results 31 to 40 of about 4,332 (253)
Scientific Reports, 2021 Duchenne muscular dystrophy (DMD) is a common and severe X-linked myopathy, characterized by muscle degeneration due to altered or absent dystrophin. DMD has no effective cure, and the underlying molecular mechanisms remain incompletely understood.
Ivana Dabaj +14 more
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Hemagglutinating activity of phosphatidylserine [PDF]
FEBS Letters, 1983 In [l] we reported the structure and hemagglutinating activity of an ornithine-containing lipid of Bordetella pertussis. The proposed structure of the aminolipid is 3-hydroxyhexadecanoic acid amide-linked to ornithine and esterified to the second hexadecanoic acid. The aminolipid strongly agglutinated human and rabbit erythrocytes. Here, I describe the
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Cell Reports, 2017 Exercise improves whole-body metabolic health through adaptations to various tissues, including adipose tissue, but the effects of exercise training on the lipidome of white adipose tissue (WAT) and brown adipose tissue (BAT) are unknown.
Francis J. May +12 more
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Scientific Reports, 2023 Dental calculus is a valuable resource for the reconstruction of dietary habits and oral microbiome of past populations. In 2020 the remains of Duke Alessandro Farnese and his wife Maria D’Aviz were exhumed to get novel insights into the causes of death.
Nicolo’ Riboni +5 more
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On the coordination of La3+ by phosphatidylserine
Biophysical Journal, 1989 In a recent study by Bentz, J., D. Alford, J. Cohen, and N. Düzgünes (1988. Biophys. J. 53:593-607), La3+ was found to be more effective than Ca2+ in causing nonleaky fusion of phosphatidylserine vesicles. It was proposed that this difference in fusion efficiency may be due, in part, to a difference in coordination of the two cations. That is, Ca2+ was
Petersheim, M., Sun, J.
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Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency
Cell Reports, 2017 Defective lysosomal function defines many neurodegenerative diseases, such as neuronal ceroid lipofuscinoses (NCL) and Niemann-Pick type C (NPC), and is implicated in Alzheimer’s disease (AD) and frontotemporal lobar degeneration (FTLD-TDP) with ...
Bret M. Evers +13 more
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Lipids in Health and Disease, 2022 Background Recent findings show that extracellular vesicle constituents can exert short- and long-range biological effects on neighboring cells in the brain, opening an exciting avenue for investigation in the field of neurodegenerative diseases ...
Melissa R. Pergande +6 more
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Role of Annexin A1 in NLRP3 Inflammasome Activation in Murine Neutrophils
Cells, 2021 This study evaluated the role of endogenous and exogenous annexin A1 (AnxA1) in the activation of the NLRP3 inflammasome in isolated peritoneal neutrophils.
José Marcos Sanches +9 more
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Journal of Lipid Research, 2021 Recent studies have highlighted an important role for lysophosphatidylcholine acyltransferase 3 (LPCAT3) in controlling the PUFA composition of cell membranes in the liver and intestine.
Thibaut Bourgeois +20 more
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Phosphatidylserine hide-and-seek [PDF]
Proceedings of the National Academy of Sciences, 2018 Every day, billions of new cells are produced in our bodies, and an equivalent number must die. Normally this occurs by apoptosis (1), during which the chromatin compacts against the nuclear envelope, followed rapidly by nuclear fragmentation and budding into multiple membrane-bound apoptotic bodies. This “dance of death” results from the activation of
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