Results 51 to 60 of about 31,210 (332)

Procoagulant Activity of Blood and Endothelial Cells via Phosphatidylserine Exposure and Microparticle Delivery in Patients with Diabetic Retinopathy

Cellular Physiology and Biochemistry, 2018
Background/Aims: The mechanisms for thrombosis in diabetic retinopathy (DR) are complex and need to be further elucidated. The purpose of this study was to test phosphatidylserine (PS) exposure on microparticles (MPs) and MP-origin cells from the ...
Ying Su, Jingli Chen, Zengxiang Dong, Yan Zhang, Ruishuang Ma, Junjie Kou, Feng Wang, Jialan Shi   +7 more
doaj   +1 more source

Muscle metabolic remodelling patterns in Duchenne muscular dystrophy revealed by ultra-high-resolution mass spectrometry imaging

Scientific Reports, 2021
Duchenne muscular dystrophy (DMD) is a common and severe X-linked myopathy, characterized by muscle degeneration due to altered or absent dystrophin. DMD has no effective cure, and the underlying molecular mechanisms remain incompletely understood.
Ivana Dabaj, Justine Ferey, Florent Marguet, Vianney Gilard, Carole Basset, Youssef Bahri, Anne-Claire Brehin, Catherine Vanhulle, France Leturcq, Stéphane Marret, Annie Laquerrière, Isabelle Schmitz-Afonso, Carlos Afonso, Soumeya Bekri, Abdellah Tebani   +14 more
doaj   +1 more source

Changeover from signalling to energy-provisioning lipids during transition from colostrum to mature milk in the giant panda (Ailuropoda melanoleuca) [PDF]

, 2016
Among the large placental mammals, ursids give birth to the most altricial neonates with the lowest neonatal:maternal body mass ratios. This is particularly exemplified by giant pandas.
Hou, Rong, Kennedy, Malcolm W., Loeffler, I. Kati, Watson, David G., Zhang, Rong, Zhang, Tong   +5 more
core   +1 more source

Sensing Phosphatidylserine in Cellular Membranes [PDF]

Sensors, 2011
Phosphatidylserine, a phospholipid with a negatively charged head-group, is an important constituent of eukaryotic cellular membranes. On the plasma membrane, rather than being evenly distributed, phosphatidylserine is found preferentially in the inner leaflet. Disruption of this asymmetry, leading to the appearance of phosphatidylserine on the surface
Jason G. Kay, Sergio Grinstein
openaire   +3 more sources

Untargeted UPLC-MS Profiling Pipeline to Expand Tissue Metabolome Coverage: Application to Cardiovascular Disease. [PDF]

, 2015
Metabolic profiling studies aim to achieve broad metabolome coverage in specific biological samples. However, wide metabolome coverage has proven difficult to achieve, mostly because of the diverse physicochemical properties of small molecules ...
Alun H. Davies, Beltran A., Cubbon S., Elaine Holmes, Eliasson M., Elizabeth J. Want, Fahy E., Geier F. M., Gika H. G., Gika H. G., Giorgis Isaac, Gray N., Hao Z., Idborg H., Ismail N. A., Ivanisevic J., Jeremy K. Nicholson, Kanehisa M., Masson P., Mirnezami R., Muzaffar A. Anwar, Naz S., Nicholson J. K., Panagiotis A. Vorkas, Plumb R. S., Saric J., Schmidt C., Smith C. A., Spagou K., Spagou K., Vorkas P. A., Waldram A., Want E. J., Wishart D. S.   +33 more
core   +5 more sources

Hemagglutinating activity of phosphatidylserine [PDF]

FEBS Letters, 1983
In [l] we reported the structure and hemagglutinating activity of an ornithine-containing lipid of Bordetella pertussis. The proposed structure of the aminolipid is 3-hydroxyhexadecanoic acid amide-linked to ornithine and esterified to the second hexadecanoic acid. The aminolipid strongly agglutinated human and rabbit erythrocytes. Here, I describe the
openaire   +2 more sources

Role of Annexin A1 in NLRP3 Inflammasome Activation in Murine Neutrophils

Cells, 2021
This study evaluated the role of endogenous and exogenous annexin A1 (AnxA1) in the activation of the NLRP3 inflammasome in isolated peritoneal neutrophils.
José Marcos Sanches, Rebeca D. Correia-Silva, Gustavo H. B. Duarte, Anna Maria A. P. Fernandes, Salvador Sánchez-Vinces, Patrícia O. Carvalho, Sonia M. Oliani, Karina R. Bortoluci, Vanessa Moreira, Cristiane D. Gil   +9 more
doaj   +1 more source

Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis. [PDF]

, 2016
ObjectiveTo determine whether characterisation of patients' metabolic profiles, utilising nuclear magnetic resonance (NMR) and mass spectrometry (MS), could predict response to rituximab therapy. 23 patients with active, seropositive rheumatoid arthritis
Boyle, David, Guma, Monica, Kavanaugh, Arthur, Lodi, Alessia, Sweeney, Shannon R, Tiziani, Stefano, Wang, Bo   +6 more
core   +2 more sources

Production and analysis of multiply charged negative ions by liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry [PDF]

, 2020
RATIONALE: Liquid AP-MALDI has been shown to enable the production of ESI-like multiply charged analyte ions with little sample consumption and long-lasting, robust ion yield for sensitive analysis by mass spectrometry. Previous reports have focused on
Brown, Jeffery M., Cramer, Rainer, Hale, Oliver J., Morris, Michael, Ryumin, Pavel   +4 more
core   +1 more source

Ultra-high performance liquid chromatography high-resolution mass spectrometry for metabolomic analysis of dental calculus from Duke Alessandro Farnese and Maria D’Aviz

Scientific Reports, 2023
Dental calculus is a valuable resource for the reconstruction of dietary habits and oral microbiome of past populations. In 2020 the remains of Duke Alessandro Farnese and his wife Maria D’Aviz were exhumed to get novel insights into the causes of death.
Nicolo’ Riboni, Federica Bianchi, Monica Mattarozzi, Marianna Peracchia, Marco Meleti, Maria Careri   +5 more
doaj   +1 more source