Results 41 to 50 of about 22,245,183 (290)
Ideal observer analysis of crowding and the reduction of crowding through learning
Journal of Vision, 2010 Crowding is a prominent phenomenon in peripheral vision where nearby objects impede one's ability to identify a target of interest. The precise mechanism of crowding is not known. We used ideal observer analysis and a noise-masking paradigm to identify the functional mechanism of crowding.
Gerald J, Sun +2 more
openaire +2 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2021 In the recent Covid-19 state of affairs, we need to spot the most huddled place and stop the mass unfold of the virus. As countries around the world begin to ease their restrictions, places as various as public areas and high streets, transport hubs, events and attractions, yet as individual offices, face the challenge of reopening safely.
Sayyed Husain Saddique +3 more
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Evaluation Of Existing Software For Simulating Of Crowd At Masjid Al-Haram, [PDF]
, 2007 Crowd simulation has played an important role in solving situations such as building evacuation, crowd congestion, and pedestrian analysis. In order to improve the crowd congestion problem within and the surrounding area of the Masjid Al-Haram, we need a
Haron, F. +3 more
core +1 more source
Crowd counting using a self‐attention multi‐scale cascaded network
IET Computer Vision, 2019 Recent developments of crowd analysis and behaviour prediction have attracted much attention. Crowd counting, as the essential and challenging task in crowd analysis, is riddled with many issues, such as large scale variations, serious occlusion, and so ...
He Li, Shihui Zhang, Weihang Kong
doaj +1 more source
Frontiers in Psychology, 2022 In the era of the global village, crowd sourcing as a new model of service outsourcing is increasingly being valued by all walks of life. This study uses the data envelopment analysis (DEA) method to explain the crowd sourcing competitiveness of service ...
Xiangdong Shen +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source