Results 121 to 130 of about 313,279 (304)

Macromolecular crowding effects in crowded biomolecular environments

open access: yes, 2018
In dieser Arbeit werden Computer-Simulationen eingesetzt um den Einfluss biologisch relevanter, konzentrierter Umgebungen auf das strukturelle Gleichgewicht von (Bio-)Polymeren zu untersuchen. Für diese Simulationen wird ein zuvor beschriebener Monte Carlo Algorithmus verwendet, welcher die Flexibilität der Moleküle anhand von strukturellen Ensembles ...
openaire   +3 more sources

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Entrepreneurship, Economic Risks, and Risk Insurance in the Welfare State: Results with OECD Data 1978-93 [PDF]

open access: yes
We find evidence in the OECD cross-country data to support the Knightian view that non-diversifiable economic risks shape equilibrium entrepreneurship in an occupational choice model.
Pekka Ilmakunnas, Vesa Kanniainen
core  

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

open access: yesAdvanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang   +8 more
wiley   +1 more source

Capital Inflow into Developing Economies: A Macroeconomic Study [PDF]

open access: yes
External capital inflow on a massive scale into the emerging market economies is a very significant phenomenon of recent years. Making distinctions between direct investment, real and financial, and portfolio investment and incorporating crowding in or ...
Soumyen Sikdar
core  

Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors

open access: yesAdvanced Science, EarlyView.
A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano   +14 more
wiley   +1 more source

Crowding Out or Crowding In? Evidence on Debt-Equity Substitutability [PDF]

open access: yes
When the composition of assets outstanding in the market changes, the pattern of expected asset returns also changes, shifting to whatever return structure will induce investors to hold just the new composition of exisiting assets.
Benjamin M. Friedman
core  

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

open access: yesAdvanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang   +7 more
wiley   +1 more source

Pursuing Manufacturing-BasedExport-Led Growth: Are Developing Countries Increasingly Crowding Each Other Out? [PDF]

open access: yes
This study empirically investigates the presence of crowding out effects emerging from intra-developing country competition in export markets for manufactured goods. Export equations are estimated for a panel consisting of twenty major developing country
Arslan Razmi
core  

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