Results 131 to 140 of about 122,762 (315)
How are molecular crowding and the spatial organization of a biopolymer interrelated
, 2016 In a crowded cellular interior, dissolved biomolecules or crowders exert excluded volume effects on other biomolecules, which in turn control various processes including protein aggregation and chromosome organization.
정영균 +3 more
core
Advanced Science, EarlyView.Faster phenol photolysis at the air–water interface arises from two cooperative factors: a more favorable initial microenvironment for solvent‐side electron stabilization, which lowers CI access, and a more labile hydrogen‐bond network, which more readily reorganizes to stabilize the dark‐state intermediate.
Qiang Yin +8 more
wiley +1 more source
Advanced Science, EarlyView.Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He +9 more
wiley +1 more source
Advanced Science, EarlyView.To accelerate the inverse design of heterostructured metal matrix composites, a closed‐loop scientific machine learning framework integrates continual learning prediction with NSGA‐II‐PMCP optimization. The framework maps microstructural descriptors to strength, toughness, and modulus, expands high‐quality Pareto solutions, and guides experimentally ...
Zhiyan Zhong +11 more
wiley +1 more source
A Price is a signal: on intrinsic motivation and crowding-out [PDF]
If a previously unpaid activity (donating blood) is paid then we often observe that this activity is reduced. In this paper, it is hypothesised that the price offered is taken as a proxy for the "market value" of the activity.
Bolle, Friedel
core
A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Advanced Science, EarlyView.Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
A Bayesian framework for crowding effect
, 2010 In crowding, neighboring distractors impair the visual perception of a presented ta get. We study influences by the configuration of distractors on the bias to perceive the orientation of a target.
Wenfeng Chen +4 more
core +1 more source
Advanced Science, EarlyView.In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong +13 more
wiley +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Advanced Science, EarlyView.Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source