Results 31 to 40 of about 5,737 (266)
This paper presents the theoretical development of lifting surface theory for the calculation of aerodynamic airforce coefficients for cruciform-tail configurations. The cruciform tail is assumed to vibrate in simple harmonic motion in a subsonic airflow
C.W. Cheung
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Background Cumulative evidence suggests that DNA secondary structures impact DNA replication, transcription and genomic rearrangements. One of the best studied examples is the recurrent constitutional t(11;22) in humans that is mediated by potentially ...
Tsutsumi Makiko +8 more
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Insights into Cruciform Sample Design [PDF]
Four different cruciform sample designs, based on the work of Abu-Farha et al., were studied in this paper. Key features of this design are a recessed pocket with fillet and re-entrant corners. These samples were shown via digital image correlation to achieve widely differing strain values inside and outside the pocket. From the results of these tests,
A, Creuziger +4 more
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ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang +6 more
wiley +1 more source
Steel Cruciform Sample with Nitrided Arms Achieves Higher Plastic Strain in the Gauge Region
This paper describes a novel solution to increase plastic strain in the gauge region of a cruciform sample during a forming limit test. A nitriding procedure was used to increase the strength of the arms of the specimen and at the same time enabled ...
Grzegorz Mitukiewicz
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This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang +8 more
wiley +1 more source
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai +11 more
wiley +1 more source
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma +10 more
wiley +1 more source
Topical glucocorticoids and the skin-mechanisms of action: an update
The topical glucocorticoids (GCs) represent the treatment of choice for many types of inflammatory dermatoses. Despite the extensive use of this class of drugs as first line therapy the mechanism of their action is uncertain.
A. Ahluwalia
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Creep Damage Evaluation using Uniaxial Miniature Specimens for Multiaxially Damaged Components [PDF]
This study discusses a method of evaluating multiaxial creep damage for high temperature components subjected to multiaxial creep damage utilizing a miniature creep testing.
Kosaka Rui +3 more
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