Results 51 to 60 of about 40,289 (297)
Advanced Science, EarlyView.Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang +6 more
wiley +1 more source
Asparkía, 2013 La propuesta del presente trabajo es realizar un breve recorrido, acercanos a dos voces de mujer que, desde la radicalidad de la palabra poética, han padecido o reflexionado sobre la violencia.
Antonio Crespo Massieu
doaj
Lizoanca, wounds and cruel reality
Swedish Journal of Romanian StudiesPhysical and mental aggression constantly inflicted on an individual at any age is associated with the concept of torture. Torture, in its inherent sense, refers to the physical suffering caused by repeated aggression.
Gabriela Chiciudean
doaj +1 more source
Ethnologia Polona, 2023 This paper interrogates the official purveyance of exterminist rhetoric in Russia’s war on Ukraine, with a particular focus on state media discourse. Over decades, the Putin regime has constructed an overarching system of intertwined narratives about Ukraine, centred on historical and geopolitical fables and exhortations to violence, and conveyed via ...
openaire +2 more sources
Advanced Science, EarlyView.QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li +9 more
wiley +1 more source
The cruel and unusual phenomenology of solitary confinement
Frontiers in Psychology, 2014 What happens when subjects are deprived of intersubjective contact? This paper looks closely at the phenomenology and psychology of one example of that deprivation: solitary confinement.
Shaun eGallagher +2 more
doaj +1 more source
Monologue about a cruel Nawab and a daring escape
, 2019 Recording of a historical narrative about one of the ancestors of the speaker/narrator who was attempting to escape the cruel oppression of the ruling Nawab of his time. The contributor is Gohar-Ur Rehman (a 38-year old male shop owner)
Iqbal, Javid
core
Advanced Science, EarlyView.In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang +13 more
wiley +1 more source
LIÇÕES DA PANDEMIA: QUESTÕES PARA REORGANIZAÇÃO DA SOCIEDADE
Holos, 2020 Apresentamos a resenha da obra: SANTOS, Boaventura de Sousa. A Cruel Pedagogia do Vírus. São Paulo: Boitempo, 2020. (Pandemia Capital).
Gustavo Tanus Cesário de Souza
doaj +1 more source