Results 41 to 50 of about 99,347 (316)

RV Ronald H. Brown Cruise RB0701, 21 Mar-10 Apr 2007. RAPID mooring cruise report [PDF]

, 2008
This report describes the mooring operations conducted during RV Ronald H. Brown Cruise RB0701 conductedbetween 21 March 2007 and 10 April 2007.These mooring operations were completed as part of the United Kingdom Natural Environment Research Council ...
Baringer, M.O., Kanzow, T.
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Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

CFD-FEM numerical simulation analysis of ship whipping response under extreme sea conditions

Zhongguo Jianchuan Yanjiu
ObjectiveThis paper investigates the coupling effect of ship nonlinear wave load and transient high-amplitude slamming load in view of the whipping response of ships under extreme sea conditions.
Hantao ZHANG, Yiwen WANG, Xiangshao KONG, Cheng ZHENG, Weiguo WU   +4 more
doaj   +1 more source

Navigating the Campus [PDF]

Social Sciences and Education Research Review
The research in this paper reviews the literature on students with disabilities (SWDs) in higher education to assess their access to education. show the need for every instructor and educational institution to ensure that students' needs are meet ...
Easaw Alemayehu ASSEFA, Chehos Kebede ZENEBE   +1 more
doaj   +1 more source

Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan

Emerging Infectious Diseases, 2020
An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages ...
Takuya Adachi, Ja-Mun Chong, Noriko Nakajima, Masahiro Sano, Jun Yamazaki, Ippei Miyamoto, Haruka Nishioka, Hidetaka Akita, Yuko Sato, Michiyo Kataoka, Harutaka Katano, Minoru Tobiume, Tsuyoshi Sekizuka, Kentaro Itokawa, Makoto Kuroda, Tadaki Suzuki   +15 more
doaj   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Numerical analysis of bubble coalescence characteristics on wetting surface

Zhongguo Jianchuan Yanjiu
ObjectiveThis study aims to advance the development of composite drag reduction technology involving super-hydrophobic surfaces and bubbles by investigating the coalescence characteristics of bubbles on wetting surfaces and revealing the effects of ...
Liuming YANG, Shicheng LIU, Zhiyong PEI, Xiangshao KONG   +3 more
doaj   +1 more source

Numerical calculation of coupled damage effects on ship subjected to internal blast loading of warhead

Zhongguo Jianchuan Yanjiu, 2022
ObjectiveThis paper studies the coupled damage effects of a ship's structure due to the internal blast loading of a warhead. MethodsBlast tests with cased charge data are conducted to verify the effectiveness of the coupled SPH-FEM approach, and ...
Hu ZHOU, Xuesen YUE, Xiangshao KONG, Cheng ZHENG, Weiguo WU   +4 more
doaj   +1 more source

RRS Charles Darwin Cruise CD177, 12-29 Nov 2005. RAPID Mooring Cruise Report [PDF]

, 2006
This report describes mooring operations and underway measurements conducted during RRS Charles Darwin Cruise CD177. Cruise CD177 was conducted between 12 November 2005 and 29 November 2005.
Cunningham, S.A.
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