Results 51 to 60 of about 60,211 (314)

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

open access: yesAdvanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou   +9 more
wiley   +1 more source

Equivalent method of different grades of steel target plates under blast loads in the cabin based on plate thickness compensation

open access: yesBaozha yu Chongji
Experimental investigation of internal explosion effects on ship structures still faces fundamental challenges. The prohibitively high costs of specialized naval steel plates impose disproportionate financial burdens on experimental budgets. Additionally,
Cheng ZHENG   +6 more
doaj   +1 more source

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao   +24 more
wiley   +1 more source

Water Transport in Arctic Tourism Logistics

open access: yesАрктика и Север
The success of Arctic tourism development is associated with solving the problem of delivering tourists to the places of their interest. “The Concept for the Development of Cruise Tourism”, approved by the government of the Russian Federation in 2022 ...
Aleksandr Yu. Tsvetkov
doaj   +1 more source

Le tourisme de croisière dans le monde : permanences et recompositions

open access: yesÉtudes Caribéennes, 2011
Cruise tourism is a sector that is rapidly expanding (16 million passengers in 2011). Today, cruising remains an essentially American affair, dominated by North American clients whose preferred destination is the Caribbean Sea.
Olivier Dehoorne   +2 more
doaj   +1 more source

TRAP5 Inhibition Targeting Scar‐Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition

open access: yesAdvanced Science, EarlyView.
This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang   +13 more
wiley   +1 more source

POSEIDON Cruise 259 [POS259]: Cruise Report

open access: yes, 2001
06.04.-20.04.2000 Las Palmas, GC, Spain,09.04.-10.04 ...
openaire   +2 more sources

Heterogeneous Wettability‐Based Construction of Two‐Phase Interfaces for Underwater Reversible Adhesion

open access: yesAdvanced Science, EarlyView.
The design employs heterogeneous wettability surfaces that construct stable oil‐water interfaces to achieve robust and rapid reversible adhesion. Linear enhancement of adhesion strength is realized through multi‐interface patterning. This adhesive enables rapid on‐demand detachment within five seconds via voltage‐induced electrolysis, offering a level ...
Xiaokai Li   +11 more
wiley   +1 more source

Low Power Optoelectronic Neuromorphic Memristor for In‐Sensor Computing and Multilevel Hardware Security Communications

open access: yesAdvanced Science, EarlyView.
ABSTRACT Conventional software‐based encryption faces mounting limitations in power efficiency and security, inspiring the development of emerging neuromorphic computing hardware encryption. This study presents a hardware‐level multi‐dimensional encryption paradigm utilizing optoelectronic neuromorphic devices with low energy consumption of 3.3 fJ ...
Bo Sun   +3 more
wiley   +1 more source

Programmable‐Stiffness Tensegrity Continuum Robot for Adaptive Multicurvature On‐Orbit Assembly

open access: yesAdvanced Intelligent Systems, EarlyView.
A bioinspired tensegrity‐based continuum robot (BTCR) with programmable stiffness enables adaptive multicurvature morphing via coordinated intra‐ and intermodule regulation. A unified energy‐based framework predicts self‐equilibrium and deformation for serial modules. Experiments and Simulations demonstrate reconfiguration into hexagonal, circular, and
Yubin Wu   +5 more
wiley   +1 more source

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