Results 221 to 230 of about 132,545 (303)

The Elbe Estuary Microbiome Shifts With Salinity and Discharge and Depends on Fresh Organic Matter and Nutrient Availability

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Microbial diversity within the Elbe Estuary was found to be more strongly governed by seasonal variability, salinity, and discharge than by spatial heterogeneity. Oligohaline regions sustain high diversity, while nutrient and redox conditions drive functional shifts.
Vanessa Russnak   +4 more
wiley   +1 more source

Minor epic: Notes toward a different “Anthropoetry”

open access: yesAnthropology and Humanism, Volume 51, Issue 1, June 2026.
Abstract Anthropologists have often turned to poetry as a means of accessing emotional registers of which conventional academic prose is unable to avail. In doing so, they have tacitly conflated poetry with lyric poetry, today probably the most widely practiced poetic genre, associated in particular with the expression of inner feelings and subjectival
Stuart McLean
wiley   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2660-2674, June 2026.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche   +8 more
wiley   +1 more source

Fenofibrate potentiates the therapeutic efficacy of EZH2 inhibitors on melanoma via TRIM21‐ and OTUD4‐mediated EZH2 ubiquitination

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2675-2694, June 2026.
Background and Purpose EZH2 (enhancer of zeste homologue 2) inhibitors are an emerging class of drugs that target epigenetic regulation. However, their efficacy in solid tumours has been limited, partly due to drug‐induced upregulation of fatty acid synthesis.
Rui Cheng   +10 more
wiley   +1 more source

TRAP5 Inhibition Targeting Scar‐Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang   +13 more
wiley   +1 more source

Low Power Optoelectronic Neuromorphic Memristor for In‐Sensor Computing and Multilevel Hardware Security Communications

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Conventional software‐based encryption faces mounting limitations in power efficiency and security, inspiring the development of emerging neuromorphic computing hardware encryption. This study presents a hardware‐level multi‐dimensional encryption paradigm utilizing optoelectronic neuromorphic devices with low energy consumption of 3.3 fJ ...
Bo Sun   +3 more
wiley   +1 more source

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