Results 171 to 180 of about 1,401 (256)

A Comprehensive 19F NMR Framework for Fragment‐Based Drug Discovery: The Validated Screening Library OpenFL600 and Efficient Affinity Ranking by CSAR

open access: yesAngewandte Chemie, EarlyView.
NMR screening is a powerful method for hit detection in drug‐discovery. We designed and validated the OpenFL600 19F$^{19}{\rm F}$ NMR library to probe diverse targets, including RNA, GPCRs, kinases, and proteases. This library yields target‐specific ligands without generating promiscuous binders.
Simon H. Rüdisser   +16 more
wiley   +2 more sources

Evolutionary analysis and population dynamics in the global transmission of Kaposi's sarcoma-associated herpesvirus. [PDF]

open access: yesArch Virol
Wang T   +8 more
europepmc   +1 more source

On Religious Influence in Bioethics: The Limits of Pluriversalism. [PDF]

open access: yesBioethics
Spitale G   +14 more
europepmc   +1 more source

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